Yasodha Natkunam, M.D., Ph.D
Publications
- CD137 ligand is expressed in primary and secondary lymphoid follicles and in B-cell lymphomas: diagnostic and therapeutic implications. Am J Surg Pathol. 2013; (2): 250-8
- Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation. Nat Commun. 2013: 1338
- CD137 is expressed in follicular dendritic cell tumors and in classical Hodgkin and T-cell lymphomas: diagnostic and therapeutic implications. Am J Pathol. 2012; (3): 795-803
- Clinicopathological features of aggressive B-cell lymphomas including B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell and Burkitt lymphomas: a study of 44 patients from Argentina. Ann Diagn Pathol. 2013; (3): 250-5
- Follicular lymphoma in young adults: a clinicopathological and molecular study of 200 patients. Mod Pathol. 2013
- Indolent T-lymphoblastic proliferation (iT-LBP): a review of clinical and pathologic features and distinction from malignant T-lymphoblastic lymphoma. Adv Anat Pathol. 2013; (3): 137-40
- Integration of genomic medicine into pathology residency training: the stanford open curriculum. J Mol Diagn. 2013; (2): 141-8
- Selective immunophenotyping for diagnosis of B-cell neoplasms: immunohistochemistry and flow cytometry strategies and results. Appl Immunohistochem Mol Morphol. 2013; (2): 116-31
- Syk-induced phosphatidylinositol-3-kinase activation in Epstein-Barr virus posttransplant lymphoproliferative disorder. Am J Transplant. 2013; (4): 883-90
- The spectrum of lymphoblastic, nodal and extranodal T-cell lymphomas: characteristic features and diagnostic dilemmas. Hum Pathol. 2013; (4): 451-71
- Usefulness of HGAL and LMO2 Immunohistochemistry in the Identification of Follicular Lymphomas of the Non-Gastric Gastrointestinal Tract. Appl Immunohistochem Mol Morphol. 2013; (3): 200-4
- Aggressive EBV-associated lymphoproliferative disorder: a prodrome to diffuse large B-cell lymphoma? Appl Immunohistochem Mol Morphol. 2012; (3): 325-30
- Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes Dev. 2012; (18): 2075-87
- Expression of the CD2AP adaptor molecule in normal, reactive and neoplastic human tissue. Pathologica. 2012; (2): 56-64
- Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma. Blood. 2012; (23): 5478-91
- IgG4-related systemic sclerosing disease of the ocular adnexa: a potential mimic of ocular lymphoma. Am J Clin Pathol. 2012; (5): 699-711
- LIM domain only 2 protein expression, LMO2 germline genetic variation, and overall survival in diffuse large B-cell lymphoma in the pre-rituximab era. Leuk Lymphoma. 2012; (6): 1105-12
- Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma. Ann Oncol. 2012; (3): 736-42
- TdT+ T-lymphoblastic populations are increased in Castleman disease, in Castleman disease in association with follicular dendritic cell tumors, and in angioimmunoblastic T-cell lymphoma. Am J Surg Pathol. 2012; (11): 1619-28
- The contribution of HGAL/GCET2 in immunohistological algorithms: a comparative study in 424 cases of nodal diffuse large B-cell lymphoma. Mod Pathol. 2012; (11): 1439-45
- The spectrum of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma: a description of 10 cases. Mod Pathol. 2012; (5): 661-74
- Clinicopathologic and molecular features of 122 Brazilian cases of nodal and extranodal NK/T-cell lymphoma, nasal type, with EBV subtyping analysis. Am J Surg Pathol. 2011; (8): 1195-203
- HGAL protein expression persists in disorders of germinal center dissolution: potential role of HGAL in the germinal center microenvironment. Appl Immunohistochem Mol Morphol. 2011; (3): 266-72
- Immunostaining to identify molecular subtypes of diffuse large B-cell lymphoma in a population-based epidemiologic study in the pre-rituximab era. Int J Mol Epidemiol Genet. 2011; (3): 245-52
- LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma. Leuk Lymphoma. 2011; (6): 1146-9
- MicroRNAs are independent predictors of outcome in diffuse large B-cell lymphoma patients treated with R-CHOP. Clin Cancer Res. 2011; (12): 4125-35
- Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment. Blood. 2011; (5): 1350-8
- T-cell lymphomas: a tale of heterogeneity masking clarity. Leuk Lymphoma. 2011; (1): 1-2
- The efficacy of HGAL and LMO2 in the separation of lymphomas derived from small B cells in nodal and extranodal sites, including the bone marrow. Am J Clin Pathol. 2011; (5): 697-708
- Building "tissue" microarrays from suspension cells. Methods Mol Biol. 2010: 93-101
- C-C chemokine receptor 1 expression in human hematolymphoid neoplasia. Am J Clin Pathol. 2010; (3): 473-83
- CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas. Hum Pathol. 2010; (2): 271-80
- Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes. Mod Pathol. 2010; (3): 420-33
- Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma. Proc Natl Acad Sci U S A. 2010; (29): 13069-74
- Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion. Arterioscler Thromb Vasc Biol. 2010; (5): 984-91
- Expression of LMO2 is associated with t(14;18)/IGH-BCL2 fusion but not BCL6 translocations in diffuse large B-cell lymphoma. Am J Clin Pathol. 2010; (2): 278-81
- Immunoarchitectural patterns in follicular lymphoma: efficacy of HGAL and LMO2 in the detection of the interfollicular and diffuse components. Am J Surg Pathol. 2010; (9): 1266-76
- Lymphoma cell VEGFR2 expression detected by immunohistochemistry predicts poor overall survival in diffuse large B cell lymphoma treated with immunochemotherapy (R-CHOP). Br J Haematol. 2010; (2): 235-44
- Oral and extraoral plasmablastic lymphoma: similarities and differences in clinicopathologic characteristics. Am J Clin Pathol. 2010; (5): 710-9
- PD-1 expression in T-cell lymphomas and reactive lymphoid entities: potential overlap in staining patterns between lymphoma and viral lymphadenitis. Am J Surg Pathol. 2010; (2): 178-89
- Programmed death 1 expression in variant immunoarchitectural patterns of nodular lymphocyte predominant Hodgkin lymphoma: comparison with CD57 and lymphomas in the differential diagnosis. Hum Pathol. 2010; (12): 1726-34
- The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation. Haematologica. 2010; (3): 432-9
- Characterization of c-Maf transcription factor in normal and neoplastic hematolymphoid tissue and its relevance in plasma cell neoplasia. Am J Clin Pathol. 2009; (3): 361-71
- Extracellular signal-regulated kinase positively regulates the oncogenic activity of MCT-1 in diffuse large B-cell lymphoma. Cancer Res. 2009; (19): 7835-43
- Gray zones around diffuse large B cell lymphoma. Conclusions based on the workshop of the XIV meeting of the European Association for Hematopathology and the Society of Hematopathology in Bordeaux, France. J Hematop. 2009; (4): 211-36
- Human germinal center-associated lymphoma protein expression is associated with improved failure-free survival in Brazilian patients with classical Hodgkin lymphoma. Leuk Lymphoma. 2009; (11): 1830-6
- Immunoarchitectural patterns in nodal marginal zone B-cell lymphoma: a study of 51 cases. Am J Clin Pathol. 2009; (1): 39-49
- Lack of utility of CD20 immunohistochemistry in staging bone marrow biopsies for diffuse large B-cell lymphoma. Appl Immunohistochem Mol Morphol. 2009; (2): 93-5
- Low stage follicular lymphoma: biologic and clinical characterization according to nodal or extranodal primary origin. Am J Surg Pathol. 2009; (4): 591-8
- Microtubule-associated protein-2 is a sensitive marker of primary and metastatic neuroblastoma. Am J Surg Pathol. 2009; (11): 1695-704
- Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens. Nat Med. 2009; (5): 566-71
- The transcription factor LMO2 is a robust marker of vascular endothelium and vascular neoplasms and selected other entities. Am J Clin Pathol. 2009; (2): 264-78
- Tissue microarrays from bone marrow aspirates for high-throughput assessment of immunohistologic markers in pediatric acute leukemia. Pediatr Dev Pathol. 2008 Jul-Aug; (4): 283-90
- Expression of HGAL in primary cutaneous large B-cell lymphomas: evidence for germinal center derivation of primary cutaneous follicular lymphoma. Mod Pathol. 2008; (6): 653-9
- Expression of the human germinal-centre-associated lymphoma protein in diffuse large B-cell lymphomas in patients with rheumatoid arthritis. Br J Haematol. 2008; (1): 69-72
- Immunohistochemical characterization of nasal-type extranodal NK/T-cell lymphoma using a tissue microarray: an analysis of 84 cases. Am J Clin Pathol. 2008; (3): 343-51
- LMO2 protein expression predicts survival in patients with diffuse large B-cell lymphoma treated with anthracycline-based chemotherapy with and without rituximab. J Clin Oncol. 2008; (3): 447-54
- PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling. Blood. 2008; (10): 4098-108
- Paraffin-based 6-gene model predicts outcome in diffuse large B-cell lymphoma patients treated with R-CHOP. Blood. 2008; (12): 5509-14
- Prognostic significance of VEGF, VEGF receptors, and microvessel density in diffuse large B cell lymphoma treated with anthracycline-based chemotherapy. Lab Invest. 2008; (1): 38-47
- The Stanford Tissue Microarray Database. Nucleic Acids Res. 2008; (Database issue): D871-7
- Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms. Haematologica. 2007; (2): 176-83
- Expression of the human germinal center-associated lymphoma (HGAL) protein identifies a subset of classic Hodgkin lymphoma of germinal center derivation and improved survival. Blood. 2007; (1): 298-305
- International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia. Leukemia. 2007; (5): 956-64
- Mast cell tryptase and microphthalmia transcription factor effectively discriminate cutaneous mast cell disease from myeloid leukemia cutis. J Cutan Pathol. 2007; (4): 289-95
- Microvessel density and expression of vascular endothelial growth factor and its receptors in diffuse large B-cell lymphoma subtypes. Am J Pathol. 2007; (4): 1362-9
- Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. Am J Pathol. 2007; (5): 1793-805
- Selective loss of B-cell phenotype in lymphocyte predominant Hodgkin lymphoma. J Pathol. 2007; (4): 429-40
- The biology of the germinal center. Hematology Am Soc Hematol Educ Program. 2007: 210-5
- The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas. Blood. 2007; (4): 1636-42
- The utility of PAX5 immunohistochemistry in the diagnosis of undifferentiated malignant neoplasms. Mod Pathol. 2007; (8): 871-7
- Bringing pathobiology into focus. Lab Invest. 2006; (7): 632
- CD10 expression in peripheral T-cell lymphomas complicated by a proliferation of large B-cells. Mod Pathol. 2006; (3): 337-43
- EBV can protect latently infected B cell lymphomas from death receptor-induced apoptosis. J Immunol. 2006; (5): 3283-93
- Jaw1/LRMP, a germinal centre-associated marker for the immunohistological study of B-cell lymphomas. J Pathol. 2006; (4): 454-63
- Loss of CD19 expression in B-cell neoplasms. Histopathology. 2006; (3): 239-46
- Low CD27 expression in plasma cell dyscrasias correlates with high-risk disease: an immunohistochemical analysis. Am J Clin Pathol. 2006; (4): 545-51
- Prognostic immunohistologic markers in human tumors: why are so few used in clinical practice? Lab Invest. 2006; (8): 742-7
- The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas. Haematologica. 2006; (6): 772-80
- Transmembrane adaptor molecules: a new category of lymphoid-cell markers. Blood. 2006; (1): 213-21
- Treatment of verruca vulgaris with topical cidofovir in an immunocompromised patient: a case report and review of the literature. Transpl Infect Dis. 2005 Sep-Dec; (3-4): 158-61
- A novel method for making "tissue" microarrays from small numbers of suspension cells. Appl Immunohistochem Mol Morphol. 2005; (1): 80-4
- Cytologic diagnosis of Burkitt lymphoma. Cancer. 2005; (5): 310-8
- Expression of CD163 (hemoglobin scavenger receptor) in normal tissues, lymphomas, carcinomas, and sarcomas is largely restricted to the monocyte/macrophage lineage. Am J Surg Pathol. 2005; (5): 617-24
- Expression of the bcl-6 and MUM1/IRF4 proteins correlate with overall and disease-specific survival in patients with primary cutaneous large B-cell lymphoma: a tissue microarray study. J Cutan Pathol. 2005; (3): 227-34
- Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation. Blood. 2005; (10): 3979-86
- Expression pattern of intracellular leukocyte-associated proteins in primary mediastinal B cell lymphoma. Leukemia. 2005; (5): 856-61
- Follicular dendritic cell immunohistochemical markers in angioimmunoblastic T-cell lymphoma. Appl Immunohistochem Mol Morphol. 2005; (4): 297-303
- Low levels of Her2/neu expressed by Ewing's family tumor cell lines can redirect cytokine-induced killer cells. Clin Cancer Res. 2005; (12): 4561-70
- TMA-Combiner, a simple software tool to permit analysis of replicate cores on tissue microarrays. Mod Pathol. 2005; (12): 1641-8
- The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas. Br J Haematol. 2005; (3): 333-42
- Utility of syndecan-1 (CD138) expression in the diagnosis of undifferentiated malignant neoplasms: a tissue microarray study of 1,754 cases. Appl Immunohistochem Mol Morphol. 2005; (4): 304-10
- Atypical cellular disorders. Hematology Am Soc Hematol Educ Program. 2004: 283-96
- Expression pattern of FCRL (FREB, FcRX) in normal and neoplastic human B cells. Br J Haematol. 2004; (3): 335-43
- Immunophenotypic and genotypic characterization of progression in follicular lymphomas. Appl Immunohistochem Mol Morphol. 2004; (2): 97-104
- Intracellular signalling molecules as immunohistochemical markers of normal and neoplastic human leucocytes in routine biopsy samples. Br J Haematol. 2004; (4): 519-33
- Characterization of variant patterns of nodular lymphocyte predominant hodgkin lymphoma with immunohistologic and clinical correlation. Am J Surg Pathol. 2003; (10): 1346-56
- Expression of the B-cell proliferation marker MUM1 by melanocytic lesions and comparison with S100, gp100 (HMB45), and MelanA. Mod Pathol. 2003; (8): 802-10
- Plasmablastic lymphoma presenting in a human immunodeficiency virus-negative patient: a case report. Ann Hematol. 2003; (8): 521-5
- Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas. Cancer Res. 2003; (15): 4472-80
- Rituximab in lymphocyte-predominant Hodgkin disease: results of a phase 2 trial. Blood. 2003; (11): 4285-9
- Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome. Leuk Lymphoma. 2002; (12): 2309-17
- Epstein-Barr virus infection is associated with endothelial Bcl-2 expression in transplant liver allografts. Transplantation. 2002; (3): 465-9
- Large atypical cells of lymphomatoid papulosis are CD56-negative: a study of 18 cases. J Cutan Pathol. 2002; (2): 88-92
- Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays. Am J Pathol. 2002; (5): 1557-65
- The usefulness of immunohistochemistry in the diagnosis of follicular lymphoma in bone marrow biopsy specimens. Am J Clin Pathol. 2002; (4): 636-43
- A unique AML1 (CBF2A) rearrangement, t(1;21)(p32;q22), observed in a patient with acute myelomonocytic leukemia. Cancer Genet Cytogenet. 2001; (2): 155-60
- Analysis of MUM1/IRF4 protein expression using tissue microarrays and immunohistochemistry. Mod Pathol. 2001; (7): 686-94
- Angiocentric lymphomas (lymphomatous vasculitis). Semin Diagn Pathol. 2001; (1): 67-77
- Durable remission in recurrent T-cell-rich B-cell lymphoma with the anti-CD20 antibody rituximab. Clin Lymphoma. 2001; (3): 185-7
- Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma. Blood. 2001; (4): 945-51
- Modified cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisone therapy for posttransplantation lymphoproliferative disease in pediatric patients undergoing solid organ transplantation. J Pediatr Hematol Oncol. 2001; (7): 452-5
- Natural killer cell precursor acute lymphoma/leukemia presenting in an infant. Arch Pathol Lab Med. 2001; (3): 413-8
- Natural killer/natural killer-like T-cell lymphoma, CD56+, presenting in the skin: an increasingly recognized entity with an aggressive course. J Clin Oncol. 2001; (8): 2179-88
- Blastic/blastoid transformation of follicular lymphoma: immunohistologic and molecular analyses of five cases. Am J Surg Pathol. 2000; (4): 525-34
- Co-expression of CD56 and CD30 in lymphomas with primary presentation in the skin: clinicopathologic, immunohistochemical and molecular analyses of seven cases. J Cutan Pathol. 2000; (8): 392-9
- Immunoblot analysis of CD34 expression in histologically diverse neoplasms. Am J Pathol. 2000; (1): 21-7
- Utility of paraffin section immunohistochemistry for C-KIT (CD117) in the differential diagnosis of systemic mast cell disease involving the bone marrow. Am J Surg Pathol. 2000; (1): 81-91
- Aggressive cutaneous NK and NK-like T-cell lymphomas: clinicopathologic, immunohistochemical, and molecular analyses of 12 cases. Am J Surg Pathol. 1999; (5): 571-81
- Aggressive natural killer-like T-cell malignancy with leukemic presentation following solid organ transplantation. Am J Clin Pathol. 1999; (5): 663-71
- Epstein-Barr virus strain type and latent membrane protein 1 gene deletions in lymphomas in patients with rheumatic diseases. Arthritis Rheum. 1997; (6): 1152-6
- Simultaneous activation of Ig and Oct-2 synthesis and reduction of surface MHC class II expression by IL-6. J Immunol. 1994; (8): 3476-84
- Nuclear signaling by interleukin-6. Curr Opin Immunol. 1993; (1): 124-8
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