Albert Koong
Publications
- Cost-effectiveness of modern radiotherapy techniques in locally advanced pancreatic cancer. Cancer. 2012; (4): 1119-29
- Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood. 2011; (4): 1311-4
- Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth. Cancer Res. 2010; (1): 78-88
- Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell. 2009; (1): 35-44
- Stereotactic radiotherapy for unresectable adenocarcinoma of the pancreas. Cancer. 2009; (3): 665-72
- The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth. Cancer Res. 2009; (3): 775-84
- X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas. Transl Oncol. 2009; (1): 31-8
- Multiplexed protein detection by proximity ligation for cancer biomarker validation. Nat Methods. 2007; (4): 327-9
- Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. Cancer Res. 2006; (11): 5816-27
- Galectin-1: a link between tumor hypoxia and tumor immune privilege. J Clin Oncol. 2005; (35): 8932-41
- The unfolded protein response: a novel component of the hypoxic stress response in tumors. Mol Cancer Res. 2005; (11): 597-605
- Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling. Cancer Res. 2004; (20): 7302-10
- Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys. 2004; (4): 1017-21
- XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Res. 2004; (17): 5943-7
- Candidate genes for the hypoxic tumor phenotype. Cancer Res. 2000; (4): 883-7
- Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev. 2000; (4): 391-6
- Pancreatic tumors show high levels of hypoxia. Int J Radiat Oncol Biol Phys. 2000; (4): 919-22
- A novel epidermal growth factor receptor variant lacking multiple domains directly activates transcription and is overexpressed in tumors. Oncogene. 2012; (24): 2953-67
- Antiangiogenic and radiation therapy: early effects on in vivo computed tomography perfusion parameters in human colon cancer xenografts in mice. Invest Radiol. 2012; (1): 25-32
- BRAF-mutated, microsatellite-stable adenocarcinoma of the proximal colon: an aggressive adenocarcinoma with poor survival, mucinous differentiation, and adverse morphologic features. Am J Surg Pathol. 2012; (5): 744-52
- Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features. Mod Pathol. 2012; (8): 1128-39
- Evaluation of the geometric accuracy of surrogate-based gated VMAT using intrafraction kilovoltage x-ray images. Med Phys. 2012; (5): 2686-93
- Intensity-modulated radiotherapy for pancreatic adenocarcinoma. Int J Radiat Oncol Biol Phys. 2012; (4): e595-601
- Intrafraction verification of gated RapidArc by using beam-level kilovoltage X-ray images. Int J Radiat Oncol Biol Phys. 2012; (5): e709-15
- Modern radiation therapy techniques for pancreatic cancer. Gastroenterol Clin North Am. 2012; (1): 223-35
- Normal tissue complication probability modeling of acute hematologic toxicity in patients treated with intensity-modulated radiation therapy for squamous cell carcinoma of the anal canal. Int J Radiat Oncol Biol Phys. 2012; (3): 700-6
- Orthovoltage intraoperative radiotherapy for locally advanced and recurrent colorectal cancer. Dis Colon Rectum. 2012; (6): 695-702
- Positron emission tomography for predicting pathologic response after neoadjuvant chemoradiotherapy for locally advanced rectal cancer. Am J Clin Oncol. 2012; (4): 334-9
- Postchemoradiotherapy positron emission tomography predicts pathologic response and survival in patients with esophageal cancer. Int J Radiat Oncol Biol Phys. 2012; (2): 471-7
- Quantitation of human papillomavirus DNA in plasma of oropharyngeal carcinoma patients. Int J Radiat Oncol Biol Phys. 2012; (3): e351-8
- WE-C-BRB-05: Monte Carlo Simulations and Experimental Validation of Rapid Dose Delivery with Very High-Energy Electron Beams. Med Phys. 2012; (6): 3944
- A novel aldehyde dehydrogenase-3 activator leads to adult salivary stem cell enrichment in vivo. Clin Cancer Res. 2011; (23): 7265-72
- Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal. Cancer. 2011; (15): 3342-51
- Stereotactic body radiation therapy for gastrointestinal malignancies. Front Radiat Ther Oncol. 2011: 412-27
- Stereotactic body radiotherapy for colorectal liver metastases: a pooled analysis. Cancer. 2011; (17): 4060-9
- Tumor galectin-1 mediates tumor growth and metastasis through regulation of T-cell apoptosis. Cancer Res. 2011; (13): 4423-31
- Unfolded protein response regulation in keloid cells. J Surg Res. 2011; (1): 151-7
- A dosimetric model of duodenal toxicity after stereotactic body radiotherapy for pancreatic cancer. Int J Radiat Oncol Biol Phys. 2010; (5): 1420-6
- Activation of the unfolded protein response in wound healing. J Surg Res. 2010; (2): 209
- Cetuximab-based immunotherapy and radioimmunotherapy of head and neck squamous cell carcinoma. Clin Cancer Res. 2010; (7): 2095-105
- Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer. Transl Oncol. 2010; (2): 109-13
- Comparison of intensity-modulated radiotherapy and 3-dimensional conformal radiotherapy as adjuvant therapy for gastric cancer. Cancer. 2010; (16): 3943-52
- EUS-guided gold fiducial insertion for image-guided radiation therapy of pancreatic cancer: 50 successful cases without fluoroscopy. Gastrointest Endosc. 2010; (3): 513-8
- Expression of p16(INK4A) but not hypoxia markers or poly adenosine diphosphate-ribose polymerase is associated with improved survival in patients with pancreatic adenocarcinoma. Cancer. 2010; (22): 5179-87
- Interfractional uncertainty in the treatment of pancreatic cancer with radiation. Int J Radiat Oncol Biol Phys. 2010; (2): 603-7
- Multimodality treatment with intensity modulated radiation therapy for esophageal cancer. Dis Esophagus. 2010; (4): 300-8
- Orthovoltage intraoperative radiation therapy for pancreatic adenocarcinoma. Radiat Oncol. 2010: 105
- Pathological response after chemoradiation for T3 rectal cancer. Colorectal Dis. 2010; (7 Online): e24-30
- The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways. PLoS One. 2010; (3): e9633
- A primer on image-guided radiation therapy for the interventional radiologist. J Vasc Interv Radiol. 2009; (7): 859-62
- Detection of solitary humeral metastasis from pancreatic adenocarcinoma with F-18 FDG PET/CT. Clin Nucl Med. 2009; (5): 312-3
- Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis. J Transl Med. 2009: 105
- Impaired interferon signaling is a common immune defect in human cancer. Proc Natl Acad Sci U S A. 2009; (22): 9010-5
- Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect. PLoS One. 2009; (9): e7033
- Pancreatic tumor motion on a single planning 4D-CT does not correlate with intrafraction tumor motion during treatment. Am J Clin Oncol. 2009; (4): 364-8
- Re: "The safety and efficacy of robotic image-guided radiosurgery system treatment for intra- and extracranial lesions: a systematic review of the literature" [Radiotherapy and Oncology 89 (2009) 245-253]. Radiother Oncol. 2009; (3): 656-7
- Safety and efficacy of percutaneous fiducial marker implantation for image-guided radiation therapy. J Vasc Interv Radiol. 2009; (2): 235-9
- The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys. 2009; (2): 553-61
- Treatment of esophageal cancer based on histology: a surveillance epidemiology and end results analysis. Am J Clin Oncol. 2009; (4): 405-10
- Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice. Mol Imaging. 2008 May-Jun; (3): 139-46
- Automated contour mapping with a regional deformable model. Int J Radiat Oncol Biol Phys. 2008; (2): 599-608
- Gemcitabine chemotherapy and single-fraction stereotactic body radiotherapy for locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys. 2008; (3): 678-86
- High-dose single-fraction radiotherapy: exploiting a new biology? Int J Radiat Oncol Biol Phys. 2008; (2): 324-5
- In vivo 1H magnetic resonance spectroscopy of lactate in patients with stage IV head and neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2008; (4): 1151-7
- Initial evaluation of 18F-fluorothymidine (FLT) PET/CT scanning for primary pancreatic cancer. Eur J Nucl Med Mol Imaging. 2008; (3): 527-31
- Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer. Clin Chem. 2008; (3): 582-9
- Tissue effects after stereotactic body radiotherapy using cyberknife for patients with abdominal malignancies. Clin Oncol (R Coll Radiol). 2008; (1): 69-75
- Enhanced 4D cone-beam CT with inter-phase motion model. Med Phys. 2007; (9): 3688-95
- Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma. Head Neck. 2007; (3): 211-20
- Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys. 2007; (1): 167-75
- Impact of integrated PET/CT on variability of target volume delineation in rectal cancer. Technol Cancer Res Treat. 2007; (1): 31-6
- Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody. Eur J Nucl Med Mol Imaging. 2007; (6): 850-8
- Stereotactic body radiotherapy for unresectable pancreatic cancer. Front Radiat Ther Oncol. 2007: 386-94
- An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers. Clin Cancer Res. 2006; (5): 1507-14
- Four-dimensional cone-beam computed tomography using an on-board imager. Med Phys. 2006; (10): 3825-33
- Mature results from a randomized Phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck squamous cell carcinomas. Cancer. 2006; (9): 1940-9
- Overview of image-guided radiation therapy. Med Dosim. 2006; (2): 91-112
- Plasma osteopontin is an independent prognostic marker for head and neck cancers. J Clin Oncol. 2006; (33): 5291-7
- Reducing respiratory motion artifacts in positron emission tomography through retrospective stacking. Med Phys. 2006; (7): 2632-41
- Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors. J Thorac Oncol. 2006; (8): 802-9
- Targeting XBP-1 as a novel anti-cancer strategy. Cancer Biol Ther. 2006; (7): 756-9
- A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia. Cancer Res. 2005; (14): 6151-8
- Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer. Oncogene. 2005; (43): 6555-63
- Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. Mol Cancer Res. 2005; (12): 669-77
- Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys. 2005; (2): 320-3
- Radiation dose reduction in four-dimensional computed tomography. Med Phys. 2005; (12): 3650-60
- Identification of hypoxia regulated proteins in head and neck cancer by proteomic and tissue array profiling. Cancer Res. 2004; (20): 7302-10
- Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms. Int J Radiat Oncol Biol Phys. 2004; (1): 171-7
- Sample classification from protein mass spectrometry, by 'peak probability contrasts'. Bioinformatics. 2004; (17): 3034-44
- The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers. Clin Cancer Res. 2004; (14): 4806-12
- Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients. Int J Radiat Oncol Biol Phys. 2003; (2): 375-83
- Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. Clin Cancer Res. 2003; (1): 59-67
- Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2003; (4): 1046-54
- Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer. Int J Radiat Oncol Biol Phys. 2003; (1): 132-7
- Estimating DNA repair by sequential evaluation of head and neck tumor radiation sensitivity using the comet assay. Arch Otolaryngol Head Neck Surg. 2002; (6): 698-702
- Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment. Clin Cancer Res. 2000; (2): 480-7
- Analysis of HSF-1 phosphorylation in A549 cells treated with a variety of stresses. Int J Hyperthermia. 1994 May-Jun; (3): 371-9
- Activators of protein kinase C selectively mediate cellular cytotoxicity to hypoxic cells and not aerobic cells. Int J Radiat Oncol Biol Phys. 1994; (2): 259-65
- Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues. Cancer Res. 1994; (6): 1425-30
- Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2). Cancer Res. 1994; (20): 5273-9
- Increased cytotoxicity of chronic hypoxic cells by molecular inhibition of GRP78 induction. Int J Radiat Oncol Biol Phys. 1994; (3): 661-6
- Modulation of potassium channels by protein tyrosine kinase inhibitors. J Cell Physiol. 1994; (1): 142-8
- The regulation of GRP78 and messenger RNA levels by hypoxia is modulated by protein kinase C activators and inhibitors. Radiat Res. 1994; (1 Suppl): S60-3
- Activation of potassium channels by hypoxia and reoxygenation in the human lung adenocarcinoma cell line A549. J Cell Physiol. 1993; (2): 341-7
- Potassium-channel activation in response to low doses of gamma-irradiation involves reactive oxygen intermediates in nonexcitatory cells. Proc Natl Acad Sci U S A. 1993; (3): 908-12
- Activation of the heat shock transcription factor by hypoxia in normal and tumor cell lines in vivo and in vitro. Int J Radiat Oncol Biol Phys. 1992; (4): 891-7
- The influence of chronic anaemia on the radiosensitivity of two mouse tumours. Br J Cancer. 1991; (4): 499-502
- Therapeutic advantage of hypoxic cells in tumors: a theoretical study. J Natl Cancer Inst. 1991; (3): 178-85
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