Anthony Oro MD/PhD

Publications

• Efficacy and safety of vismodegib in advanced basal-cell carcinoma. Sekulic A, Migden MR, Oro AE, Dirix L, Lewis KD, Hainsworth JD, Solomon JA, Yoo S, Arron ST, Friedlander PA, Marmur E, Rudin CM, Chang AL, Low JA, Mackey HM, Yauch RL, Graham RA, Reddy JC, Hauschild A. N Engl J Med. 2012; 366 (23): 2171-9
• Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop. Woo WM, Zhen HH, Oro AE. Genes Dev. 2012; 26 (11): 1235-46
• Translocation affecting sonic hedgehog genes in basal-cell carcinoma. Gomez-Ospina N, Chang AL, Qu K, Oro AE. N Engl J Med. 2012; 366 (23): 2233-4
• I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration. Quinones GA, Jin J, Oro AE. J Cell Biol. 2010; 189 (2): 353-67
• MIM and cortactin antagonism regulates ciliogenesis and hedgehog signaling. Bershteyn M, Atwood SX, Woo WM, Li M, Oro AE. Dev Cell. 2010; 19 (2): 270-83
• Cell migration: GSK3β steers the cytoskeleton's tip. Yucel G, Oro AE. Cell. 2011; 144 (3): 319-21
• In vivo imaging of human and mouse skin with a handheld dual-axis confocal fluorescence microscope. Ra H, Piyawattanametha W, Gonzalez-Gonzalez E, Mandella MJ, Kino GS, Solgaard O, Leake D, Kaspar RL, Oro A, Contag CH. J Invest Dermatol. 2011; 131 (5): 1061-6
• SnapShot: hair follicle stem cells. Woo WM, Oro AE. Cell. 2011; 146 (2): 334-334.e2
• Top-accessed article: Basal cell nevus syndrome. Gomezospina N, Oro AE. Arch Dermatol. 2011; 147 (10): 1213
• BAR domain competition during directional cellular migration. Quiñones GA, Oro AE. Cell Cycle. 2010; 9 (13): 2522-8
• Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE. BMC Dev Biol. 2010: 10 112
• The primary cilium: a small yet mighty organelle. DeRouen MC, Oro AE. J Invest Dermatol. 2009; 129 (2): 264-5
• A new role for an old friend: NFAT and stem cell quiescence. Oro AE, Cell Stem Cell. 2008; 2 (2): 104-6
• Controlling hair follicle signaling pathways through polyubiquitination. Huntzicker EG, Oro AE. J Invest Dermatol. 2008; 128 (5): 1081-7
• Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP. Genes Dev. 2008; 22 (15): 2111-24
• Role of the basement membrane zone in skin development. Oro AE, J Invest Dermatol. 2008; 128 (E2): E11-2
• The primary cilia, a 'Rab-id' transit system for hedgehog signaling. Oro AE, Curr Opin Cell Biol. 2007; 19 (6): 691-6
• Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Proc Natl Acad Sci U S A. 2006; 103 (40): 14842-7
• Dual degradation signals control Gli protein stability and tumor formation. Huntzicker EG, Estay IS, Zhen H, Lokteva LA, Jackson PK, Oro AE. Genes Dev. 2006; 20 (3): 276-81
• Mammalian variations on a theme: a Smo and Sufu surprise. Oro AE, Dev Cell. 2006; 10 (2): 156-8
• Conditional telomerase induction causes proliferation of hair follicle stem cells. Sarin KY, Cheung P, Gilison D, Lee E, Tennen RI, Wang E, Artandi MK, Oro AE, Artandi SE. Nature. 2005; 436 (7053): 1048-52
• Receptor tyrosine phosphatase-dependent cytoskeletal remodeling by the hedgehog-responsive gene MIM/BEG4. Gonzalez-Quevedo R, Shoffer M, Horng L, Oro AE. J Cell Biol. 2005; 168 (3): 453-63
• MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription. Callahan CA, Ofstad T, Horng L, Wang JK, Zhen HH, Coulombe PA, Oro AE. Genes Dev. 2004; 18 (22): 2724-9
• Hair cycle regulation of Hedgehog signal reception. Oro AE, Higgins K. Dev Biol. 2003; 255 (2): 238-48
• Laminin-10 is crucial for hair morphogenesis. Li J, Tzu J, Chen Y, Zhang YP, Nguyen NT, Gao J, Bradley M, Keene DR, Oro AE, Miner JH, Marinkovich MP. EMBO J. 2003; 22 (10): 2400-10
• Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. Aszterbaum M, Epstein J, Oro A, Douglas V, LeBoit PE, Scott MP, Epstein EH. Nat Med. 1999; 5 (11): 1285-91