Linda Boxer
Publications
- The immunoglobulin heavy chain gene 3' enhancers induce Bcl2 deregulation and lymphomagenesis in murine B cells. Leukemia. 2011; (9): 1484-93
- Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. Oncogene. 2008; (53): 6720-8
- Activation of the c-myc p1 promoter in Burkitt's lymphoma by the hs3 immunoglobulin heavy-chain gene enhancer. Leukemia. 2007; (4): 747-53
- Protein/DNA arrays identify nitric oxide-regulated cis-element and trans-factor activities some of which govern neuroblastoma cell viability. Nucleic Acids Res. 2007; (16): 5439-51
- The immunoglobulin heavy-chain gene 3' enhancers deregulate bcl-2 promoter usage in t(14;18) lymphoma cells. Oncogene. 2007; (18): 2635-41
- Oct transcription factors mediate t(14;18) lymphoma cell survival by directly regulating bcl-2 expression. Oncogene. 2006; (6): 888-98
- Role of the cyclic AMP response element in the bcl-2 promoter in the regulation of endogenous Bcl-2 expression and apoptosis in murine B cells. Mol Cell Biol. 2006; (22): 8599-606
- Transcription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivo. FASEB J. 2006; (6): 800-2
- A genome-wide view of the in vitro response to l-asparaginase in acute lymphoblastic leukemia. Cancer Res. 2005; (1): 291-9
- CCAAT/enhancer binding protein alpha (C/EBPalpha) and C/EBPalpha myeloid oncoproteins induce bcl-2 via interaction of their basic regions with nuclear factor-kappaB p50. Mol Cancer Res. 2005; (10): 585-96
- Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas. Mol Cell Biol. 2005; (5): 1608-19
- Regulatory elements in the immunoglobulin heavy chain gene 3'-enhancers induce c-myc deregulation and lymphomagenesis in murine B cells. J Biol Chem. 2005; (13): 12766-73
- Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia. Blood. 2004; (3): 1043-9
- Neurotrophin-3 and a CREB-mediated signaling pathway regulate Bcl-2 expression in oligodendrocyte progenitor cells. J Neurochem. 2004; (4): 951-61
- Critical elements of the immunoglobulin heavy chain gene enhancers for deregulated expression of bcl-2. Cancer Res. 2003; (20): 6666-73
- Cytokine-mediated down-regulation of the transcription factor cAMP-response element-binding protein in pancreatic beta-cells. J Biol Chem. 2003; (25): 23055-65
- Oxidative stress-mediated down-regulation of bcl-2 promoter in hippocampal neurons. J Neurochem. 2003; (5): 982-96
- Regulation of Bcl-2 expression by C/EBP in t(14;18) lymphoma cells. Oncogene. 2003; (39): 7891-9
- A Myc-associated zinc finger protein-related factor binding site is required for the deregulation of c-myc expression by the immunoglobulin heavy chain gene enhancers in Burkitt's lymphoma. J Biol Chem. 2002; (12): 9819-24
- Allele-specific analysis of transcription factors binding to promoter regions. Methods. 2002; (1): 19-26
- Impaired proliferation and survival of activated B cells in transgenic mice that express a dominant-negative cAMP-response element-binding protein transcription factor in B cells. J Biol Chem. 2002; (50): 48359-65
- NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells. Oncogene. 2002; (24): 3898-908
- Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma. Cancer Res. 2001; (13): 5202-6
- Negative regulation of bcl-2 expression by p53 in hematopoietic cells. Oncogene. 2001; (2): 240-51
- Suppression of apoptosis and granulocyte colony-stimulating factor-induced differentiation by an oncogenic form of Cbl. Exp Hematol. 2001; (6): 746-55
- The critical role of the PE21 element in oncostatin M-mediated transcriptional repression of the p53 tumor suppressor gene in breast cancer cells. Oncogene. 2001; (57): 8193-202
- The cyclic AMP response element in the Bcl-2 promoter confers inducibility by hypoxia in neuronal cells. Brain Res Mol Brain Res. 2001; (1-2): 98-106
- Translocations involving c-myc and c-myc function. Oncogene. 2001; (40): 5595-610
- A-Myb up-regulates Bcl-2 through a Cdx binding site in t(14;18) lymphoma cells. J Biol Chem. 2000; (9): 6499-508
- Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein. J Biol Chem. 2000; (15): 10761-6
- NF-kappa B activity is required for the deregulation of c-myc expression by the immunoglobulin heavy chain enhancer. J Biol Chem. 2000; (41): 32338-46
- Nerve growth factor- and epidermal growth factor-regulated gene transcription in PC12 pheochromocytoma and INS-1 insulinoma cells. Eur J Cell Biol. 2000; (12): 924-35
- A zinc-finger transcription factor induced by TGF-beta promotes apoptotic cell death in epithelial Mv1Lu cells. FEBS Lett. 1999; (3): 478-82
- Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade. Nucleic Acids Res. 1999; (10): 2086-90
- Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein. J Biol Chem. 1999; (39): 27529-35
- The expression of p53 tumor suppressor gene in breast cancer cells is down-regulated by cytokine oncostatin M. Cell Growth Differ. 1999; (10): 677-83
- p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor. J Biol Chem. 1999; (21): 15237-44
- Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor. J Biol Chem. 1998; (27): 16715-22
- The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression. Nucleic Acids Res. 1998; (18): 4100-7
- Identification of the major positive regulators of c-myb expression in hematopoietic cells of different lineages. J Biol Chem. 1997; (3): 1943-9
- The WT1 protein is a negative regulator of the normal bcl-2 allele in t(14;18) lymphomas. J Biol Chem. 1997; (31): 19609-14
- CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas. J Biol Chem. 1996; (37): 22687-91
- Identification of an inducible regulator of c-myb expression during T-cell activation. Mol Cell Biol. 1996; (5): 2387-93
- Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis. Mol Cell Biol. 1996; (10): 5546-56
- Myb binding sites mediate negative regulation of c-myb expression in T-cell lines. Blood. 1995; (5): 1873-80
- Pi 1 binding sites are negative regulators of bcl-2 expression in pre-B cells. Mol Cell Biol. 1995; (7): 3840-7
- Repression of the c-myb gene by WT1 protein in T and B cell lines. J Biol Chem. 1995; (40): 23785-9
- The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma. J Biol Chem. 1995; (22): 13392-8
- Activation of c-myc expression by c-Abl is independent of both the DNA binding function of c-Abl and the c-myc EP site. J Biol Chem. 1994; (34): 21919-24
- Differential protein binding to the c-myc promoter during differentiation of hematopoietic cell lines. Oncogene. 1994; (9): 2699-706
- NF-kappa B sites function as positive regulators of expression of the translocated c-myc allele in Burkitt's lymphoma. Mol Cell Biol. 1994; (12): 7967-74
- The role of oncogenes in hematologic malignancies. Annu Rev Med. 1994: 1-11
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