Peter Jackson
Publications
- A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Cell Cycle. 2013; (4): 625-34
- Alkylsulfanyl-1,2,4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure-activity relationships. J Med Chem. 2013; (2): 437-50
- Cilia, tubby mice, and obesity. Cilia. 2013; (1): 1
- Our thanks to Cilia's reviewers. Cilia. 2013; (1): 4
- The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell. 2013; (1-2): 210-23
- Cilia - the prodigal organelle. Cilia. 2012; (1): 1
- Cilia develop long-lasting contacts, with other cilia. Cilia. 2012; (1): 5
- Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc Natl Acad Sci U S A. 2012; (14): 5299-304
- TTBK2 kinase: linking primary cilia and cerebellar ataxias. Cell. 2012; (4): 697-9
- A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation. Mol Biol Cell. 2011; (4): 448-56
- An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium. Genes Dev. 2011; (22): 2347-60
- Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry. Mol Cell. 2011; (4): 511-23
- Do cilia put brakes on the cell cycle? Nat Cell Biol. 2011; (4): 340-2
- Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics. PLoS One. 2011; (8): e22607
- Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011; (4): 513-28
- Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proc Natl Acad Sci U S A. 2011; (7): 2759-64
- Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. Nature. 2011; (7336): 110-4
- The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly. Cell. 2011; (6): 1309-23
- The tubby family proteins. Genome Biol. 2011; (6): 225
- A chemosensitization screen identifies TP53RK, a kinase that restrains apoptosis after mitotic stress. Cancer Res. 2010; (15): 6325-35
- A specific form of phospho protein phosphatase 2 regulates anaphase-promoting complex/cyclosome association with spindle poles. Mol Biol Cell. 2010; (6): 897-904
- APC/C(Cdc20) targets E2F1 for degradation in prometaphase. Cell Cycle. 2010; (19): 3956-64
- Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet. 2010; (10): 840-50
- Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. J Clin Invest. 2010; (3): 791-802
- TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Genes Dev. 2010; (19): 2180-93
- Biochemical analysis of the Anaphase Promoting Complex: activities of E2 enzymes and substrate competitive (pseudosubstrate) inhibitors. Methods Mol Biol. 2009: 313-30
- High-throughput generation of tagged stable cell lines for proteomic analysis. Proteomics. 2009; (10): 2888-91
- Navigating the deubiquitinating proteome with a CompPASS. Cell. 2009; (2): 222-4
- A BBSome subunit links ciliogenesis, microtubule stability, and acetylation. Dev Cell. 2008; (6): 854-65
- Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. Mol Biol Cell. 2008; (8): 3536-43
- Emi1 protein accumulation implicates misregulation of the anaphase promoting complex/cyclosome pathway in ovarian clear cell carcinoma. Mod Pathol. 2008; (4): 445-54
- New ligands for melanocortin receptors. Int J Obes (Lond). 2008: S19-27
- Stopping replication, at the beginning. Nat Chem Biol. 2008; (6): 331-2
- The hunt for cyclin. Cell. 2008; (2): 199-202
- The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells. Cell Cycle. 2008; (9): 1184-90
- The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC. Mol Cell. 2008; (4): 544-56
- A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling. Cell. 2007; (4): 611-23
- A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell. 2007; (6): 1201-13
- A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. Curr Biol. 2007; (3): 213-24
- Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Proc Natl Acad Sci U S A. 2007; (42): 16564-9
- Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). J Cell Biol. 2007; (3): 371-85
- Emi2 at the crossroads: where CSF meets MPF. Cell Cycle. 2007; (6): 732-8
- Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene. Proc Natl Acad Sci U S A. 2007; (4): 1236-41
- Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. Mol Cell Biol. 2007; (22): 7955-65
- Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. Am J Pathol. 2007; (5): 1793-805
- Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1). J Cell Biol. 2007; (1): 65-75
- Putting transcription repression and protein destruction in pRb's pocket. Dev Cell. 2007; (2): 169-70
- The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Dev Cell. 2007; (1): 29-42
- Translational unmasking of Emi2 directs cytostatic factor arrest in meiosis II. Cell Cycle. 2007; (6): 725-31
- CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit. Proc Natl Acad Sci U S A. 2006; (3): 608-13
- Climbing the Greatwall to mitosis. Mol Cell. 2006; (2): 156-7
- Developmental neurobiology: a destructive switch for neurons. Nature. 2006; (7101): 365-6
- Dual degradation signals control Gli protein stability and tumor formation. Genes Dev. 2006; (3): 276-81
- Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. Genes Dev. 2006; (17): 2410-20
- Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis. J Cell Biol. 2006; (6): 791-801
- Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells. Cell Cycle. 2006; (14): 1569-73
- The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1. Cell. 2006; (2): 367-80
- A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs. Proc Natl Acad Sci U S A. 2005; (12): 4318-23
- Emi1 class of proteins regulate entry into meiosis and the meiosis I to meiosis II transition in Xenopus oocytes. Cell Cycle. 2005; (3): 478-82
- Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase. J Cell Biol. 2005; (1): 61-71
- Screening of tissue microarrays for ubiquitin proteasome system components in tumors. Methods Enzymol. 2005: 334-55
- Linking tumor suppression, DNA damage and the anaphase-promoting complex. Trends Cell Biol. 2004; (7): 331-4
- Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1. Mol Biol Cell. 2004; (12): 5623-34
- Wagging the dogma; tissue-specific cell cycle control in the mouse embryo. Cell. 2004; (5): 535-8
- Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell division. BMC Cell Biol. 2004: 27
- Accessory proteins for melanocortin signaling: attractin and mahogunin. Ann N Y Acad Sci. 2003: 288-98
- Can Fizzy fly solo? Nat Cell Biol. 2003; (10): 864-5
- Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo. Dev Cell. 2003; (6): 799-812
- Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. Dev Cell. 2003; (6): 813-26
- Spongiform degeneration in mahoganoid mutant mice. Science. 2003; (5607): 710-2
- Ubiquitinating a phosphorylated Cdk inhibitor on the blades of the Cdc4 beta-propeller. Cell. 2003; (2): 142-4
- Control of the centriole and centrosome cycles by ubiquitination enzymes. Oncogene. 2002; (40): 6209-21
- Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation. Nat Cell Biol. 2002; (4): 317-22
- Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase. Mol Biol Cell. 2002; (7): 2289-300
- E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1). Nat Cell Biol. 2002; (5): 358-66
- Emi1 is required for cytostatic factor arrest in vertebrate eggs. Nature. 2002; (6883): 850-4
- The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development. Dev Biol. 2002; (2): 395-408
- The SCF ubiquitin ligase: an extended look. Mol Cell. 2002; (5): 923-5
- A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases. Genes Dev. 2001; (23): 3053-8
- Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. J Cell Biol. 2001; (6): 1267-78
- Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Cell. 2001; (5): 645-55
- Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins. Genes Dev. 2001; (24): 3278-85
- Triggering ubiquitination of a CDK inhibitor at origins of DNA replication. Nat Cell Biol. 2001; (8): 715-22
- Nuclear accumulation of cyclin E/Cdk2 triggers a concentration-dependent switch for the destruction of p27Xic1. Proc Natl Acad Sci U S A. 2000; (14): 7796-801
- The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. Trends Cell Biol. 2000; (10): 429-39
- Budding yeast Cdc6p induces re-replication in fission yeast by inhibition of SCF(Pop)-mediated proteolysis. Mol Gen Genet. 1999; (3): 473-80
- Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. Genes Dev. 1999; (17): 2242-57
- Cyclin-dependent kinase control of centrosome duplication. Proc Natl Acad Sci U S A. 1999; (6): 2817-22
- F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p. Curr Biol. 1999; (7): 373-6
- Identification of novel F-box proteins in Xenopus laevis. Curr Biol. 1999; (20): R762-3
- Cell cycle: oiling the gears of anaphase. Curr Biol. 1998; (18): R636-9
- Cell cycle: cull and destroy. Curr Biol. 1996; (10): 1209-12
- The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products. EMBO J. 1996; (7): 1583-95
- Cell cycle arrest by tyrosine kinase Abl involves altered early mitogenic response. Oncogene. 1995; (7): 1325-33
- Early events in DNA replication require cyclin E and are blocked by p21CIP1. J Cell Biol. 1995; (4): 755-69
- Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature. 1995; (6520): 386-8
- Mitosis in transition. Cell. 1994; (4): 563-71
- The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity. J Cell Biol. 1994; (3): 325-40
- Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl. Oncogene. 1993; (7): 1943-56
- Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line. Mol Cell Biol. 1992; (4): 1864-71
- Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo. Mol Cell Biol. 1992; (2): 609-18
- Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell. 1991; (7): 1153-63
- The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity. Proc Natl Acad Sci U S A. 1991; (2): 627-31
Help
Trial Administration