Lei Xing
Publications
- Registration of onboard x-ray images with 4DCT for phase verification and setup of gated radiotherapy, in press European Journal of Medical Physics.
- Image-guided resection of malignant gliomas using fluorescent nanoparticles. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013 May-Jun; (3): 219-32
- An adaptive planning strategy for station parameter optimized radiation therapy (SPORT): Segmentally boosted VMAT. Med Phys. 2013; (5): 050701
- Automatic Prostate Tracking and Motion Assessment in Volumetric Modulated Arc Therapy With an Electronic Portal Imaging Device. Int J Radiat Oncol Biol Phys. 2013
- Development and clinical evaluation of automatic fiducial detection for tumor tracking in cine megavoltage images during volumetric modulated arc therapy. Med Phys. 2013; (3): 031708
- Development of XFCT imaging strategy for monitoring the spatial distribution of platinum-based chemodrugs: instrumentation and phantom validation. Med Phys. 2013; (3): 030701
- Dosimetric analysis of organs at risk during expiratory gating in stereotactic body radiation therapy for pancreatic cancer. Int J Radiat Oncol Biol Phys. 2013; (4): 1090-5
- First study of on-treatment volumetric imaging during respiratory gated VMAT. Med Phys. 2013; (4): 040701
- Point/counterpoint. DASSIM-RT is likely to become the method of choice over conventional IMRT and VMAT for delivery of highly conformal radiotherapy. Med Phys. 2013; (2): 020601
- Single-scan patient-specific scatter correction in computed tomography using peripheral detection of scatter and compressed sensing scatter retrieval. Med Phys. 2013; (1): 011907
- X-ray acoustic computed tomography with pulsed x-ray beam from a medical linear accelerator. Med Phys. 2013; (1): 010701
- X-ray excitable luminescent polymer dots doped with an iridium(III) complex. Chem Commun (Camb). 2013; (39): 4319-21
- An end-to-end examination of geometric accuracy of IGRT using a new digital accelerator equipped with onboard imaging system. Phys Med Biol. 2012; (3): 757-69
- Dose optimization with first-order total-variation minimization for dense angularly sampled and sparse intensity modulated radiation therapy (DASSIM-RT). Med Phys. 2012; (7): 4316-27
- Efficient IMRT inverse planning with a new L1-solver: template for first-order conic solver. Phys Med Biol. 2012; (13): 4139-53
- Evaluation of the geometric accuracy of surrogate-based gated VMAT using intrafraction kilovoltage x-ray images. Med Phys. 2012; (5): 2686-93
- Improved compressed sensing-based cone-beam CT reconstruction using adaptive prior image constraints. Phys Med Biol. 2012; (8): 2287-307
- Intrafraction verification of gated RapidArc by using beam-level kilovoltage X-ray images. Int J Radiat Oncol Biol Phys. 2012; (5): e709-15
- Intraoperative imaging of tumors using Cerenkov luminescence endoscopy: a feasibility experimental study. J Nucl Med. 2012; (10): 1579-84
- Radioluminescence microscopy: measuring the heterogeneous uptake of radiotracers in single living cells. PLoS One. 2012; (10): e46285
- Real-time tumor motion estimation using respiratory surrogate via memory-based learning. Phys Med Biol. 2012; (15): 4771-86
- Response to "comment on 'bridging the gap between IMRT and VMAT: dense angularly sampled and sparse intensity modulated radiation therapy'" [Med. Phys. 38, 4912-4919 (2011)]. Med Phys. 2012; (3): 1676
- Scatter correction in cone-beam CT via a half beam blocker technique allowing simultaneous acquisition of scatter and image information. Med Phys. 2012; (5): 2386-95
- Tracking the motion trajectories of junction structures in 4D CT images of the lung. Phys Med Biol. 2012; (15): 4905-30
- A Bayesian approach to real-time 3D tumor localization via monoscopic x-ray imaging during treatment delivery. Med Phys. 2011; (7): 4205-14
- Automated detection of junctions structures and tracking of their trajectories in 4D images. Inf Process Med Imaging. 2011: 486-97
- Bridging the gap between IMRT and VMAT: dense angularly sampled and sparse intensity modulated radiation therapy. Med Phys. 2011; (9): 4912-9
- Dose verification for respiratory-gated volumetric modulated arc therapy. Phys Med Biol. 2011; (15): 4827-38
- GPU computing in medical physics: a review. Med Phys. 2011; (5): 2685-97
- In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma. NMR Biomed. 2011; (5): 506-13
- Inverse planning for IMRT with nonuniform beam profiles using total-variation regularization (TVR). Med Phys. 2011; (1): 57-66
- Limited-angle x-ray luminescence tomography: methodology and feasibility study. Phys Med Biol. 2011; (12): 3487-502
- Metal artifact reduction in x-ray computed tomography (CT) by constrained optimization. Med Phys. 2011; (2): 701-11
- Monte Carlo simulation of photon migration in a cloud computing environment with MapReduce. J Biomed Opt. 2011; (12): 125003
- Synthesis and radioluminescence of PEGylated Eu(3+) -doped nanophosphors as bioimaging probes. Adv Mater. 2011; (24): H195-9
- Toward real-time Monte Carlo simulation using a commercial cloud computing infrastructure. Phys Med Biol. 2011; (17): N175-81
- Ultrafast and scalable cone-beam CT reconstruction using MapReduce in a cloud computing environment. Med Phys. 2011; (12): 6603-9
- A binary image reconstruction technique for accurate determination of the shape and location of metal objects in x-ray computed tomography. J Xray Sci Technol. 2010; (4): 403-14
- A failure detection strategy for intrafraction prostate motion monitoring with on-board imagers for fixed-gantry IMRT. Int J Radiat Oncol Biol Phys. 2010; (3): 904-11
- A unified framework for 3D radiation therapy and IMRT planning: plan optimization in the beamlet domain by constraining or regularizing the fluence map variations. Phys Med Biol. 2010; (22): N521-31
- Clinical development of a failure detection-based online repositioning strategy for prostate IMRT--experiments, simulation, and dosimetry study. Med Phys. 2010; (10): 5287-97
- Compressed sensing based cone-beam computed tomography reconstruction with a first-order method. Med Phys. 2010; (9): 5113-25
- Dose reconstruction for volumetric modulated arc therapy (VMAT) using cone-beam CT and dynamic log files. Phys Med Biol. 2010; (13): 3597-610
- Fast and accurate marker-based projective registration method for uncalibrated transmission electron microscope tilt series. Phys Med Biol. 2010; (12): 3417-40
- Hybrid x-ray/optical luminescence imaging: characterization of experimental conditions. Med Phys. 2010; (8): 4011-8
- Image-based modeling of tumor shrinkage in head and neck radiation therapy. Med Phys. 2010; (5): 2351-8
- In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma. NMR Biomed. 2010
- Inverse planning for four-dimensional (4D) volumetric modulated arc therapy. Med Phys. 2010; (11): 5627-33
- Optimized hybrid megavoltage-kilovoltage imaging protocol for volumetric prostate arc therapy. Int J Radiat Oncol Biol Phys. 2010; (2): 595-604
- Sinogram preprocessing and binary reconstruction for determination of the shape and location of metal objects in computed tomography (CT). Med Phys. 2010; (11): 5867-75
- Tomographic molecular imaging of x-ray-excitable nanoparticles. Opt Lett. 2010; (20): 3345-7
- Toward truly optimal IMRT dose distribution: inverse planning with voxel-specific penalty. Technol Cancer Res Treat. 2010; (6): 629-36
- X-ray luminescence computed tomography via selective excitation: a feasibility study. IEEE Trans Med Imaging. 2010; (12): 1992-9
- Beam's-eye-view Dosimetrics-guided inverse planning for aperture-modulated arc therapy. Int J Radiat Oncol Biol Phys. 2009; (5): 1587-95
- Four-dimensional inverse treatment planning with inclusion of implanted fiducials in IMRT segmented fields. Med Phys. 2009; (6): 2215-21
- Image-guided radiotherapy in near real time with intensity-modulated radiotherapy megavoltage treatment beam imaging. Int J Radiat Oncol Biol Phys. 2009; (2): 603-10
- Iterative image reconstruction for CBCT using edge-preserving prior. Med Phys. 2009; (1): 252-60
- Medical Physics Iterative image reconstruction for CBCT using edge-preserving prior. 2009: 252-260
- Noise suppression in scatter correction for cone-beam CT. Med Phys. 2009; (3): 741-52
- Pancreatic tumor motion on a single planning 4D-CT does not correlate with intrafraction tumor motion during treatment. Am J Clin Oncol. 2009; (4): 364-8
- Predicting respiratory tumor motion with multi-dimensional adaptive filters and support vector regression. Phys Med Biol. 2009; (19): 5735-48
- Scatter correction for cone-beam CT in radiation therapy. Med Phys. 2009; (6): 2258-68
- Search for IMRT inverse plans with piecewise constant fluence maps using compressed sensing techniques. Med Phys. 2009; (5): 1895-905
- Tissue feature-based and segmented deformable image registration for improved modeling of shear movement of lungs. Int J Radiat Oncol Biol Phys. 2009; (4): 1256-65
- Use of MV and kV imager correlation for maintaining continuous real-time 3D internal marker tracking during beam interruptions. Phys Med Biol. 2009; (1): 89-103
- Multiscale registration of planning CT and daily cone beam CT images for adaptive radiation therapy Multiscale registration of planning CT and daily cone beam CT images for adaptive radiation therapy. 2009: 4-11
- 4D-4D Image registration for image guided radiation therapy (IGRT) International Journal of Radiation Oncology, Biology and Physics. 2008: 578-586
- A fiducial detection algorithm for real-time image guided IMRT based on simultaneous MV and kV imaging. Med Phys. 2008; (8): 3554-64
- Auto-mapping of rectum contour for prostate adaptive therapy inverse planning Medical Physics. 2008; (accepted)
- Auto-propagation of contours for adaptive prostate radiation therapy. Phys Med Biol. 2008; (17): 4533-42
- Automated contour mapping with a regional deformable model. Int J Radiat Oncol Biol Phys. 2008; (2): 599-608
- Combined kV and MV imaging for real-time tracking of implanted fiducial markers. Med Phys. 2008; (4): 1191-8
- Contour propagation from planning CT to cone beam CT (CBCT) Physics in Medicine and Biology. 2008: 4533-4542
- Design of multi-purpose phantom and automated software analysis tool for quality assurance of onboard kV/MV imaging system Medical Physics. 2008: 1497-1506
- Development of a QA phantom and automated analysis tool for geometric quality assurance of on-board MV and kV x-ray imaging systems. Med Phys. 2008; (4): 1497-506
- Dose reduction for kilovotage cone-beam computed tomography in radiation therapy. Phys Med Biol. 2008; (11): 2897-909
- Dose reduction in kV cone beam CT for radiation therapy Physics in Medicine and Biology. 2008: 2897-2909
- Fast fiducial detection algorithm for onboard MV and kV imaging systems Medical Physics. 2008: 1942-1949
- Fast internal marker tracking algorithm for onboard MV and kV imaging systems. Med Phys. 2008; (5): 1942-9
- Feature-based rectal contour propagation from planning CT to cone beam CT. Med Phys. 2008; (10): 4450-9
- Individualized gating windows based on four-dimensional CT information for respiration-gated radiotherapy. Phys Med Biol. 2008; (1): 165-75
- Intrafractional motion of the prostate during hypofractionated radiotherapy. Int J Radiat Oncol Biol Phys. 2008; (1): 236-46
- MRI-based treatment planning with electron density information mapped from CT images: a preliminary study. Technol Cancer Res Treat. 2008; (5): 341-8
- Quality assurance of PET/CT for radiation therapy International Journal of Radiation Oncology, Biology and Physics. 2008: S38-41
- Quality assurance of positron emission tomography/computed tomography for radiation therapy. Int J Radiat Oncol Biol Phys. 2008; (1 Suppl): S38-42
- Real-time 3D internal marker tracking during arc radiotherapy by the use of combined MV-kV imaging. Phys Med Biol. 2008; (24): 7197-213
- Real-time monitoring of implanted fiducials using onboard kV and treatment MV beams Medical Physics. 2008: 1191-1198
- Reducing respiratory motion artifacts in radionuclide imaging through retrospective stacking: A simulation study Linear Algebra and its Applications. 2008: 1325-1344
- Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file. Int J Radiat Oncol Biol Phys. 2008; (2): 634-44
- The use of EPID-measured leaf sequence files for IMRT dose reconstruction in adaptive radiation therapy. Med Phys. 2008; (11): 5019-29
- Using total-variation regularization for intensity modulated radiation therapy inverse planning with field-specific numbers of segments. Phys Med Biol. 2008; (23): 6653-72
- Pancreatic tumor motion on a single planning 4D-CT dose not correlate with intrafraction tumor motion during treatment, in press Pancreatic tumor motion on a single planning 4D-CT dose not correlate with intrafraction tumor motion during treatment, in press. 2008
- Objective assessment of deformable image registration in radiotherapy: Amulti-institution study Objective assessment of deformable image registration in radiotherapy: Amulti-institution study. 2008: 5944-5953
- Noise suppression in scatter correction for cone-beam CT, in press Noise suppression in scatter correction for cone-beam CT, in press. 2008
- Modeling the shear movement of the lungs during respiration using tissue feature-based image registration, conditionally accepted Modeling the shear movement of the lungs during respiration using tissue feature-based image registration, conditionally accepted. 2008
- Dose reduction in fluoscopic imaging, conditionally accepted Dose reduction in fluoscopic imaging, conditionally accepted. 2008
- In vivo bioluminescence tumor imaging of RGD peptide-modified adenoviral vector encoding firefly luciferase reporter gene. Mol Imaging Biol. 2007 May-Jun; (3): 126-34
- Automated contour mapping using sparse volume sampling for 4D radiation therapy. Med Phys. 2007; (10): 4023-9
- CT image registration in sinogram space. Med Phys. 2007; (9): 3596-602
- Computational challenges for image-guided radiation therapy: framework and current research. Semin Radiat Oncol. 2007; (4): 245-57
- Enhanced 4D cone-beam CT with inter-phase motion model. Med Phys. 2007; (9): 3688-95
- Evaluation of on-board kV cone beam CT (CBCT)-based dose calculation. Phys Med Biol. 2007; (3): 685-705
- Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma. Head Neck. 2007; (3): 211-20
- Examination of geometric and dosimetric accuracies of gated step-and-shoot intensity modulated radiation therapy. Med Phys. 2007; (10): 3962-70
- Formulating adaptive radiation therapy (ART) treatment planning into a closed-loop control framework. Phys Med Biol. 2007; (14): 4137-53
- Hybrid Multiscale Landmark and Deformable Image Registration Mathematical Biosciences and Engineering. 2007: 711 –737
- Investigation of linac-based image-guided hypofractionated prostate radiotherapy. Med Dosim. 2007; (2): 71-9
- Optimizing 4D cone-beam CT acquisition protocol for external beam radiotherapy. Int J Radiat Oncol Biol Phys. 2007; (4): 1211-9
- Point/Counterpoint. Kilovoltage imaging is more suitable than megavoltage imaging for guiding radiation therapy. Med Phys. 2007; (12): 4563-6
- 18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer. J Nucl Med. 2006; (3): 492-501
- Combination of integrin siRNA and irradiation for breast cancer therapy. Biochem Biophys Res Commun. 2006; (3): 726-32
- Four-dimensional cone-beam computed tomography using an on-board imager. Med Phys. 2006; (10): 3825-33
- Image interpolation in 4D CT using a BSpline deformable registration model. Int J Radiat Oncol Biol Phys. 2006; (5): 1537-50
- Image registration with auto-mapped control volumes. Med Phys. 2006; (4): 1165-79
- Indirect MR lymphangiography of the head and neck using conventional gadolinium contrast: a pilot study in humans. Int J Radiat Oncol Biol Phys. 2006; (2): 462-8
- Model-based image reconstruction for four-dimensional PET. Med Phys. 2006; (5): 1288-98
- Motion correction for improved target localization with on-board cone-beam computed tomography. Phys Med Biol. 2006; (2): 253-67
- Multiscale image registration. Math Biosci Eng. 2006; (2): 389-418
- Multistage image registration (figures featured in the cover of the issue of the journal) Mathematical Biosciences and Engineering. 2006; (1): 389-418
- Overview of image-guided radiation therapy. Med Dosim. 2006; (2): 91-112
- Reducing respiratory motion artifacts in positron emission tomography through retrospective stacking. Med Phys. 2006; (7): 2632-41
- Scatter correction method for X-ray CT using primary modulation: theory and preliminary results. IEEE Trans Med Imaging. 2006; (12): 1573-87
- Dose-volume based ranking of incident beam direction and its utility in facilitating IMRT beam placement. Int J Radiat Oncol Biol Phys. 2005; (2): 584-93
- In vivo prostate magnetic resonance spectroscopic imaging using two-dimensional J-resolved PRESS at 3 T. Magn Reson Med. 2005; (5): 1177-82
- Measurement of ionizing radiation using carbon nanotube field effect transistor. Phys Med Biol. 2005; (3): N23-31
- Narrow band deformable registration of prostate magnetic resonance imaging, magnetic resonance spectroscopic imaging, and computed tomography studies. Int J Radiat Oncol Biol Phys. 2005; (2): 595-605
- Optical detection of tumors in vivo by visible light tissue oximetry. Technol Cancer Res Treat. 2005; (3): 227-34
- Optimization of radiotherapy dose-time fractionation with consideration of tumor specific biology. Med Phys. 2005; (12): 3666-77
- Quantitation of the a priori dosimetric capabilities of spatial points in inverse planning and its significant implication in defining IMRT solution space. Phys Med Biol. 2005; (7): 1469-82
- Radiation dose reduction in four-dimensional computed tomography. Med Phys. 2005; (12): 3650-60
- The value of PET/CT is being over-sold as a clinical tool in radiation oncology. For the proposition. Med Phys. 2005; (6): 1457-8
- Towards biologically conformal radiation therapy (BCRT): selective IMRT dose escalation under the guidance of spatial biology distribution. Med Phys. 2005; (6): 1473-84
- Clinical knowledge-based inverse treatment planning. Phys Med Biol. 2004; (22): 5101-17
- Feasibility study of beam orientation class-solutions for prostate IMRT. Med Phys. 2004; (10): 2863-70
- Incorporating model parameter uncertainty into inverse treatment planning. Med Phys. 2004; (9): 2711-20
- Inverse treatment planning with adaptively evolving voxel-dependent penalty scheme. Med Phys. 2004; (10): 2839-44
- Mapping of the prostate in endorectal coil-based MRI/MRSI and CT: a deformable registration and validation study. Med Phys. 2004; (11): 3087-94
- Quantitative measurement of MLC leaf displacements using an electronic portal image device. Phys Med Biol. 2004; (8): 1521-33
- IMRT dose shaping with regionally variable penalty scheme. Med Phys. 2003; (4): 544-51
- Incorporating leaf transmission and head scatter corrections into step-and-shoot leaf sequences for IMRT. Int J Radiat Oncol Biol Phys. 2003; (4): 1121-34
- Independent dosimetric calculation with inclusion of head scatter and MLC transmission for IMRT. Med Phys. 2003; (11): 2937-47
- Quality assurance of magnetic resonance spectroscopic imaging-derived metabolic data. Int J Radiat Oncol Biol Phys. 2003; (4): 1159-73
- Segment-based dose optimization using a genetic algorithm. Phys Med Biol. 2003; (18): 2987-98
- Therapeutic treatment plan optimization with probability density-based dose prescription. Med Phys. 2003; (4): 655-66
- Using the volumetric effect of a finite-sized detector for routine quality assurance of multileaf collimator leaf positioning. Med Phys. 2003; (3): 433-41
- A three-source model for the calculation of head scatter factors. Med Phys. 2002; (9): 2024-33
- Application of constrained least-squares techniques to IMRT treatment planning. Int J Radiat Oncol Biol Phys. 2002; (4): 1217-24
- Examination of the effect of increasing the number of radiation beams on a radiation treatment plan. Phys Med Biol. 2002; (19): 3485-501
- Incorporating prior knowledge into beam orientation optimization in IMRT. Int J Radiat Oncol Biol Phys. 2002; (5): 1565-74
- Inverse planning for functional image-guided IMRT Physics in Medicine and Biology. 2002: 3567-3578
- Inverse planning for functional image-guided intensity-modulated radiation therapy. Phys Med Biol. 2002; (20): 3567-78
- Minimizing delivery time and monitor units in static IMRT by leaf-sequencing. Phys Med Biol. 2002; (17): 3105-16
- Using voxel-dependent importance factors for interactive DVH-based dose optimization. Phys Med Biol. 2002; (10): 1659-69
- Computer-assisted selection of coplanar beam orientations in intensity-modulated radiation therapy. Phys Med Biol. 2001; (9): 2467-76
- Linear algebraic methods applied to intensity modulated radiation therapy. Phys Med Biol. 2001; (10): 2587-606
- Pseudo beam's-eye-view as applied to beam orientation selection in intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2001; (5): 1361-70
- Role of beam orientation optimization in intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2001; (2): 551-60
- A dose-volume histogram based optimization algorithm for ultrasound guided prostate implants. Med Phys. 2000; (10): 2286-92
- Beam orientation optimization in intensity-modulated radiation treatment planning. Med Phys. 2000; (6): 1238-45
- Breast-conserving radiation therapy using combined electron and intensity-modulated radiotherapy technique. Radiother Oncol. 2000; (1): 65-71
- Computer verification of fluence map for intensity modulated radiation therapy. Med Phys. 2000; (9): 2084-92
- Dosimetric effects of patient displacement and collimator and gantry angle misalignment on intensity modulated radiation therapy. Radiother Oncol. 2000; (1): 97-108
- Inverse planning incorporating organ motion. Med Phys. 2000; (7): 1573-8
- Monitor unit calculation for an intensity modulated photon field by a simple scatter-summation algorithm. Phys Med Biol. 2000; (3): N1-7
- Monte Carlo verification of IMRT dose distributions from a commercial treatment planning optimization system. Phys Med Biol. 2000; (9): 2483-95
- Clinical implementation of wedge filter optimization in three-dimensional radiotherapy treatment planning. Radiother Oncol. 1999; (3): 257-64
- Dosimetric verification of a commercial inverse treatment planning system. Phys Med Biol. 1999; (2): 463-78
- Estimation theory and model parameter selection for therapeutic treatment plan optimization. Med Phys. 1999; (11): 2348-58
- Matching photon and electron fields with dynamic intensity modulation. Med Phys. 1999; (11): 2379-84
- Optimization of importance factors in inverse planning. Phys Med Biol. 1999; (10): 2525-36
- Synchronizing dynamic multileaf collimators for producing two-dimensional intensity-modulated fields with minimum beam delivery time. Int J Radiat Oncol Biol Phys. 1999; (5): 1147-54
- Theoretical considerations of monitor unit calculations for intensity modulated beam treatment planning. Med Phys. 1999; (2): 187-95
- A three-dimensional algorithm for optimizing beam weights and wedge filters. Med Phys. 1998; (10): 1858-65
- An optimized leaf-setting algorithm for beam intensity modulation using dynamic multileaf collimators. Phys Med Biol. 1998; (6): 1629-43
- Fast iterative algorithms for three-dimensional inverse treatment planning. Med Phys. 1998; (10): 1845-9
- Interference of BAD (Bcl-xL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11. Mol Endocrinol. 1997; (12): 1858-67
- Optimization of Beam Weights and Wedge Filters Medical Physics. 1997: 215-222
- Iterative Algorithms for Inverse Planning Physics in Meidicine and Bilogy. 1996: 2107-23
- Transcriptional control of the invariant chain gene involves promoter and enhancer elements common to and distinct from major histocompatibility complex class II genes. Mol Cell Biol. 1990; (8): 3906-16
- Complete sequence of the murine invariant chain (Ii) gene. Nucleic Acids Res. 1989; (1): 447-8
- Herpes simplex virus 1 helicase-primase: a complex of three herpes-encoded gene products. Proc Natl Acad Sci U S A. 1989; (7): 2186-9
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