Zijie Sun

Publications

• Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors. Kwak MK, Johnson DT, Zhu C, Lee SH, Ye DW, Luong R, Sun Z. PLoS One. 2013; 8 (1): e53476
• Deletion of leucine zipper tumor suppressor 2 (Lzts2) increases susceptibility to tumor development. Johnson DT, Luong R, Lee SH, Peng Y, Shaltouki A, Lee JT, Lin D, Wang Y, Sun Z. J Biol Chem. 2013; 288 (6): 3727-38
• Conditional expression of the androgen receptor induces oncogenic transformation of the mouse prostate. Zhu C, Luong R, Zhuo M, Johnson DT, McKenney JK, Cunha GR, Sun Z. J Biol Chem. 2011; 286 (38): 33478-88
• The beta-catenin binding protein ICAT modulates androgen receptor activity. Zhuo M, Zhu C, Sun J, Weis WI, Sun Z. Mol Endocrinol. 2011; 25 (10): 1677-88
• The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development. Peng Y, Clark C, Luong R, Tu WH, Lee J, Johnson DT, Das A, Carroll TJ, Sun Z. J Biol Chem. 2011; 286 (46): 40331-42
• ZMIZ1 preferably enhances the transcriptional activity of androgen receptor with short polyglutamine tract. Li X, Zhu C, Tu WH, Yang N, Qin H, Sun Z. PLoS One. 2011; 6 (9): e25040
• A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcription. Peng Y, Lee J, Zhu C, Sun Z. J Biol Chem. 2010; 285 (15): 11465-75
• Efficacy of c-Met inhibitor for advanced prostate cancer. Tu WH, Zhu C, Clark C, Christensen JG, Sun Z. BMC Cancer. 2010: 10 556
• Xeno-oestrogens and phyto-oestrogens are alternative ligands for the androgen receptor. Wang H, Li J, Gao Y, Xu Y, Pan Y, Tsuji I, Sun ZJ, Li XM. Asian J Androl. 2010; 12 (4): 535-47
• The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular development. Beliakoff J, Lee J, Ueno H, Aiyer A, Weissman IL, Barsh GS, Cardiff RD, Sun Z. Mol Cell Biol. 2008; 28 (1): 282-92
• A promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells. Li TH, Zhao H, Peng Y, Beliakoff J, Brooks JD, Sun Z. Nucleic Acids Res. 2007; 35 (8): 2767-76
• The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression. Verras M, Lee J, Xue H, Li TH, Wang Y, Sun Z. Cancer Res. 2007; 67 (3): 967-75
• The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor. Lee J, Beliakoff J, Sun Z. Nucleic Acids Res. 2007; 35 (13): 4523-34
• Cyclin D1 and p16 expression in recurrent nasopharyngeal carcinoma. Lin HS, Berry GJ, Sun Z, Fee WE. World J Surg Oncol. 2006: 4 62
• LZTS2 is a novel beta-catenin-interacting protein and regulates the nuclear export of beta-catenin. Thyssen G, Li TH, Lehmann L, Zhuo M, Sharma M, Sun Z. Mol Cell Biol. 2006; 26 (23): 8857-67
• Roles and regulation of Wnt signaling and beta-catenin in prostate cancer. Verras M, Sun Z. Cancer Lett. 2006; 237 (1): 22-32
• The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity. Li X, Thyssen G, Beliakoff J, Sun Z. J Biol Chem. 2006; 281 (33): 23748-56
• Zimp7 and Zimp10, two novel PIAS-like proteins, function as androgen receptor coregulators. Beliakoff J, Sun Z. Nucl Recept Signal. 2006: 4 e017
• Beta-catenin is involved in insulin-like growth factor 1-mediated transactivation of the androgen receptor. Verras M, Sun Z. Mol Endocrinol. 2005; 19 (2): 391-8
• hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes. Huang CY, Beliakoff J, Li X, Lee J, Li X, Sharma M, Lim B, Sun Z. Mol Endocrinol. 2005; 19 (12): 2915-29
• An Hsp27-related, dominant-negative-acting intracellular estradiol-binding protein. Chen H, Hewison M, Hu B, Sharma M, Sun Z, Adams JS. J Biol Chem. 2004; 279 (29): 29944-51
• Identification of tyrosine kinases overexpressed in head and neck cancer. Lin HS, Berry GJ, Fee WE, Terris DJ, Sun Z. Arch Otolaryngol Head Neck Surg. 2004; 130 (3): 311-6
• Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells. Verras M, Brown J, Li X, Nusse R, Sun Z. Cancer Res. 2004; 64 (24): 8860-6
• Mechanism of p21-activated kinase 6 (PAK6) - mediated inhibition of androgen receptor signaling Schrantz N, Fowler B, Ge Q, Sun Z, and Bokoch GM. J. Biol. Chem. 2003: 279 1922-31
• hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci. Sharma M, Li X, Wang Y, Zarnegar M, Huang CY, Palvimo JJ, Lim B, Sun Z. EMBO J. 2003; 22 (22): 6101-14
• A novel zinc finger transcription factor with two isoforms that are differentially repressed by estrogen receptor-alpha. Conroy AT, Sharma M, Holtz AE, Wu C, Sun Z, Weigel RJ. J Biol Chem. 2002; 277 (11): 9326-34
• Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members. Morotomi-Yano K, Yano K, Saito H, Sun Z, Iwama A, Miki Y. J Biol Chem. 2002; 277 (1): 836-42
• Linking beta-catenin to androgen-signaling pathway. Yang F, Li X, Sharma M, Sasaki CY, Longo DL, Lim B, Sun Z. J Biol Chem. 2002; 277 (13): 11336-44
• Regulation of androgen signaling by the phosphatidylinosital 3-kinase/Akt is mediated through GSK3beta/beta-catenin pathway Sharma M, Chuang WW, Sun ZJ. J. Biol. Chem. 2002: 277 30935-30941
• 5'TG3' interacting factor interacts with Sin3A and represses AR-mediated transcription. Sharma M, Sun Z. Mol Endocrinol. 2001; 15 (11): 1918-28
• Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6. Yang F, Li X, Sharma M, Zarnegar M, Lim B, Sun Z. J Biol Chem. 2001; 276 (18): 15345-53
• Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner. Reutens AT, Fu M, Wang C, Albanese C, McPhaul MJ, Sun Z, Balk SP, Jänne OA, Palvimo JJ, Pestell RG. Mol Endocrinol. 2001; 15 (5): 797-811
• Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family. Schuur ER, Loktev AV, Sharma M, Sun Z, Roth RA, Weigel RJ. J Biol Chem. 2001; 276 (36): 33554-60
• SMAD3 represses androgen receptor-mediated transcription. Hayes SA, Zarnegar M, Sharma M, Yang F, Peehl DM, ten Dijke P, Sun Z. Cancer Res. 2001; 61 (5): 2112-8
• Androgen receptor interacts with a novel MYST protein, HBO1. Sharma M, Zarnegar M, Li X, Lim B, Sun Z. J Biol Chem. 2000; 275 (45): 35200-8
• PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. Oettgen P, Finger E, Sun Z, Akbarali Y, Thamrongsak U, Boltax J, Grall F, Dube A, Weiss A, Brown L, Quinn G, Kas K, Endress G, Kunsch C, Libermann TA. J Biol Chem. 2000; 275 (2): 1216-25
• AP-1 mediates stretch-induced expression of HB-EGF in bladder smooth muscle cells. Park JM, Adam RM, Peters CA, Guthrie PD, Sun Z, Klagsbrun M, Freeman MR. Am J Physiol. 1999; 277 (2 Pt 1): C294-301
• Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. Iwama A, Pan J, Zhang P, Reith W, Mach B, Tenen DG, Sun Z. Mol Cell Biol. 1999; 19 (6): 3940-50
• Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Zhang P, Behre G, Pan J, Iwama A, Wara-Aswapati N, Radomska HS, Auron PE, Tenen DG, Sun Z. Proc Natl Acad Sci U S A. 1999; 96 (15): 8705-10
• Tumor susceptibility gene 101 protein represses androgen receptor transactivation and interacts with p300. Sun Z, Pan J, Hope WX, Cohen SN, Balk SP. Cancer. 1999; 86 (4): 689-96
• Tyrosine kinases expressed in vivo by human prostate cancer bone marrow metastases and loss of the type 1 insulin-like growth factor receptor. Chott A, Sun Z, Morganstern D, Pan J, Li T, Susani M, Mosberger I, Upton MP, Bubley GJ, Balk SP. Am J Pathol. 1999; 155 (4): 1271-9
• Two promoters direct expression of the murine Spi-B gene, an Ets family transcription factor. Chen HM, Gonzalez DA, Radomska HS, Voso MT, Sun Z, Zhang P, Zhang DE, Tenen DG. Gene. 1998; 207 (2): 209-18
• Androgen receptor-associated protein complex binds upstream of the androgen-responsive elements in the promoters of human prostate-specific antigen and kallikrein 2 genes. Sun Z, Pan J, Balk SP. Nucleic Acids Res. 1997; 25 (16): 3318-25
• Frequent abnormalities of TSG101 transcripts in human prostate cancer. Sun Z, Pan J, Bubley G, Balk SP. Oncogene. 1997; 15 (25): 3121-5
• Interleukin-5 receptor alpha subunit gene regulation in human eosinophil development: identification of a unique cis-element that acts lie an enhancer in regulating activity of the IL-5R alpha promoter. Sun Z, Yergeau DA, Wong IC, Tuypens T, Tavernier J, Paul CC, Baumann MA, Auron PE, Tenen DG, Ackerman SJ. Curr Top Microbiol Immunol. 1996: 211 173-87
• Identification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit gene. Sun Z, Yergeau DA, Tuypens T, Tavernier J, Paul CC, Baumann MA, Tenen DG, Ackerman SJ. J Biol Chem. 1995; 270 (3): 1462-71
• PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene. Hohaus S, Petrovick MS, Voso MT, Sun Z, Zhang DE, Tenen DG. Mol Cell Biol. 1995; 15 (10): 5830-45
• Analysis of the imperfect octamer-containing human immunoglobulin VH6 gene promoter. Sun Z, Kitchingman GR. Nucleic Acids Res. 1994; 22 (5): 850-60
• Bidirectional transcription from the human immunoglobulin VH6 gene promoter. Sun Z, Kitchingman GR. Nucleic Acids Res. 1994; 22 (5): 861-8
• Functional characterization of the promoter for the gene encoding human eosinophil peroxidase. Yamaguchi Y, Zhang DE, Sun Z, Albee EA, Nagata S, Tenen DG, Ackerman SJ. J Biol Chem. 1994; 269 (30): 19410-9
• Sequencing of selected regions of the human immunoglobulin heavy-chain gene locus that completes the sequence from JH through the delta constant region. Sun ZJ, Kitchingman GR. DNA Seq. 1991; 1 (5): 347-55