M. Peter Marinkovich

Publications

• Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP. Genes Dev. 2008; 22 (15): 2111-24
• Targeting a tumor-specific laminin domain critical for human carcinogenesis. Tran M, Rousselle P, Nokelainen P, Tallapragada S, Nguyen NT, Fincher EF, Marinkovich MP. Cancer Res. 2008; 68 (8): 2885-94
• A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation. Waterman EA, Sakai N, Nguyen NT, Horst BA, Veitch DP, Dey CN, Ortiz-Urda S, Khavari PA, Marinkovich MP. Cancer Res. 2007; 67 (9): 4264-70
• Tumour microenvironment: laminin 332 in squamous-cell carcinoma. Marinkovich MP, Nat Rev Cancer. 2007; 7 (5): 370-80
• Type VII collagen is required for Ras-driven human epidermal tumorigenesis. Ortiz-Urda S, Garcia J, Green CL, Chen L, Lin Q, Veitch DP, Sakai LY, Lee H, Marinkovich MP, Khavari PA. Science. 2005; 307 (5716): 1773-6
• Linear immunoglobulin A bullous dermatosis. Fortuna G, Marinkovich MP. Clin Dermatol. 2012 Jan-Feb; 30 (1): 38-50
• A critical reappraisal of the current data on drug-induced linear immunoglobulin A bullous dermatosis: a real and separate nosological entity? Fortuna G, Salas-Alanis JC, Guidetti E, Marinkovich MP. J Am Acad Dermatol. 2012; 66 (6): 988-94
• Molecular organization of the basement membrane zone. Hashmi S, Marinkovich MP. Clin Dermatol. 2011 Jul-Aug; 29 (4): 398-411
• Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE. BMC Dev Biol. 2010: 10 112
• Observations of skin grafts derived from keratinocytes expressing selectively engineered mutant laminin-332 molecules. Sakai N, Waterman EA, Nguyen NT, Keene DR, Marinkovich MP. J Invest Dermatol. 2010; 130 (8): 2147-50
• Role of dermal-epidermal basement membrane zone in skin, cancer, and developmental disorders. Ko MS, Marinkovich MP. Dermatol Clin. 2010; 28 (1): 1-16
• Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies. Nguyen B, Dusek RL, Beaudry VG, Marinkovich MP, Attardi LD. J Invest Dermatol. 2009; 129 (7): 1710-8
• Bridging structure with function: structural, regulatory, and developmental role of laminins. Tzu J, Marinkovich MP. Int J Biochem Cell Biol. 2008; 40 (2): 199-214
• Discovery of basement membrane components. Marinkovich MP, J Invest Dermatol. 2008; 128 (E2): E3-4
• What's new in blistering disorders? Chaudhari P, Marinkovich MP. Curr Allergy Asthma Rep. 2007; 7 (4): 255-63
• Integrin beta4 regulates migratory behavior of keratinocytes by determining laminin-332 organization. Sehgal BU, DeBiase PJ, Matzno S, Chew TL, Claiborne JN, Hopkinson SB, Russell A, Marinkovich MP, Jones JC. J Biol Chem. 2006; 281 (46): 35487-98
• Keratinocyte-secreted laminin 5 can function as a transient receptor for human papillomaviruses by binding virions and transferring them to adjacent cells. Culp TD, Budgeon LR, Marinkovich MP, Meneguzzi G, Christensen ND. J Virol. 2006; 80 (18): 8940-50
• Overexpression of laminin-8 in human dermal microvascular endothelial cells promotes angiogenesis-related functions. Li J, Zhou L, Tran HT, Chen Y, Nguyen NE, Karasek MA, Marinkovich MP. J Invest Dermatol. 2006; 126 (2): 432-40
• beta4 integrin and epidermal growth factor coordinately regulate electric field-mediated directional migration via Rac1. Pullar CE, Baier BS, Kariya Y, Russell AJ, Horst BA, Marinkovich MP, Isseroff RR. Mol Biol Cell. 2006; 17 (11): 4925-35
• A simplified laminin nomenclature. Aumailley M, Bruckner-Tuderman L, Carter WG, Deutzmann R, Edgar D, Ekblom P, Engel J, Engvall E, Hohenester E, Jones JC, Kleinman HK, Marinkovich MP, Martin GR, Mayer U, Meneguzzi G, Miner JH, Miyazaki K, Patarroyo M, Paulsson M, Quaranta V, Sanes JR, Sasaki T, Sekiguchi K, Sorokin LM, Talts JF, Tryggvason K, Uitto J, Virtanen I, von der Mark K, Wewer UM, Yamada Y, Yurchenco PD. Matrix Biol. 2005; 24 (5): 326-32
• Involvement of p53 and p16 tumor suppressor genes in recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma. Arbiser JL, Fan CY, Su X, Van Emburgh BO, Cerimele F, Miller MS, Harvell J, Marinkovich MP. J Invest Dermatol. 2004; 123 (4): 788-90
• Kinetics and specificity of fas ligand induction in toxic epidermal necrolysis. Chang HY, Cooper ZA, Swetter SM, Marinkovich MP. Arch Dermatol. 2004; 140 (2): 242-4
• Mature human thymocytes migrate on laminin-5 with activation of metalloproteinase-14 and cleavage of CD44. Vivinus-Nebot M, Rousselle P, Breittmayer JP, Cenciarini C, Berrih-Aknin S, Spong S, Nokelainen P, Cottrez F, Marinkovich MP, Bernard A. J Immunol. 2004; 172 (3): 1397-406
• Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin. Russell AJ, Fincher EF, Millman L, Smith R, Vela V, Waterman EA, Dey CN, Guide S, Weaver VM, Marinkovich MP. J Cell Sci. 2003; 116 (Pt 17): 3543-56
• Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors. Zahir N, Lakins JN, Russell A, Ming W, Chatterjee C, Rozenberg GI, Marinkovich MP, Weaver VM. J Cell Biol. 2003; 163 (6): 1397-407
• Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue. Ortiz-Urda S, Lin Q, Green CL, Keene DR, Marinkovich MP, Khavari PA. J Clin Invest. 2003; 111 (2): 251-5
• Laminin-10 is crucial for hair morphogenesis. Li J, Tzu J, Chen Y, Zhang YP, Nguyen NT, Gao J, Bradley M, Keene DR, Oro AE, Miner JH, Marinkovich MP. EMBO J. 2003; 22 (10): 2400-10
• Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin. Veitch DP, Nokelainen P, McGowan KA, Nguyen TT, Nguyen NE, Stephenson R, Pappano WN, Keene DR, Spong SM, Greenspan DS, Findell PR, Marinkovich MP. J Biol Chem. 2003; 278 (18): 15661-8
• NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Dajee M, Lazarov M, Zhang JY, Cai T, Green CL, Russell AJ, Marinkovich MP, Tao S, Lin Q, Kubo Y, Khavari PA. Nature. 2003; 421 (6923): 639-43
• Topical tacrolimus is a useful adjunctive therapy for bullous pemphigoid. Chu J, Bradley M, Marinkovich MP. Arch Dermatol. 2003; 139 (6): 813-5
• Epidermolysis bullosa: new and emerging trends. Pai S, Marinkovich MP. Am J Clin Dermatol. 2002; 3 (6): 371-80
• The first international consensus on mucous membrane pemphigoid: definition, diagnostic criteria, pathogenic factors, medical treatment, and prognostic indicators. Chan LS, Ahmed AR, Anhalt GJ, Bernauer W, Cooper KD, Elder MJ, Fine JD, Foster CS, Ghohestani R, Hashimoto T, Hoang-Xuan T, Kirtschig G, Korman NJ, Lightman S, Lozada-Nur F, Marinkovich MP, Mondino BJ, Prost-Squarcioni C, Rogers RS, Setterfield JF, West DP, Wojnarowska F, Woodley DT, Yancey KB, Zillikens D, Zone JJ. Arch Dermatol. 2002; 138 (3): 370-9
• Linear IgA bullous dermatosis. Guide SV, Marinkovich MP. Clin Dermatol. 2001 Nov-Dec; 19 (6): 719-27
• A spontaneous canine model of mucous membrane (cicatricial) pemphigoid, an autoimmune blistering disease affecting mucosae and mucocutaneous junctions. Olivry T, Dunston SM, Schachter M, Xu L, Nguyen N, Marinkovich MP, Chan LS. J Autoimmun. 2001; 16 (4): 411-21
• IgG anti-LABD97 antibodies in bullous pemphigoid patients' sera react with the mid-portion of the BPAg2 ectodomain. Egan CA, Reddy D, Nie Z, Taylor TB, Schmidt LA, Meyer LJ, Petersen MJ, Hashimoto T, Marinkovich MP, Zone JJ. J Invest Dermatol. 2001; 116 (2): 348-50
• Properties of the collagen type XVII ectodomain. Evidence for n- to c-terminal triple helix folding. Areida SK, Reinhardt DP, Muller PK, Fietzek PP, Kowitz J, Marinkovich MP, Notbohm H. J Biol Chem. 2001; 276 (2): 1594-601
• Autoantibodies against the processed ectodomain of collagen XVII (BPAG2, BP180) define a canine homologue of linear IgA disease of humans. Olivry T, Dunston SM, Fahey M, Nguyen N, Marinkovich MP. Vet Pathol. 2000; 37 (4): 302-9
• Autoantibodies to BP180 associated with bullous pemphigoid release interleukin-6 and interleukin-8 from cultured human keratinocytes. Schmidt E, Reimer S, Kruse N, Jainta S, Bröcker EB, Marinkovich MP, Giudice GJ, Zillikens D. J Invest Dermatol. 2000; 115 (5): 842-8
• Laminins and human disease. McGowan KA, Marinkovich MP. Microsc Res Tech. 2000; 51 (3): 262-79
• Subepidermal blistering disease with autoantibodies against a novel dermal 200-kDa antigen. Kawahara Y, Zillikens D, Yancey KB, Marinkovich MP, Nie Z, Hashimoto T, Nishikawa T. J Dermatol Sci. 2000; 23 (2): 93-102
• BP180 gene delivery in junctional epidermolysis bullosa. Seitz CS, Giudice GJ, Balding SD, Marinkovich MP, Khavari PA. Gene Ther. 1999; 6 (1): 42-7
• Bullous systemic lupus erythematosus with autoantibodies recognizing multiple skin basement membrane components, bullous pemphigoid antigen 1, laminin-5, laminin-6, and type VII collagen. Chan LS, Lapiere JC, Chen M, Traczyk T, Mancini AJ, Paller AS, Woodley DT, Marinkovich MP. Arch Dermatol. 1999; 135 (5): 569-73
• Compound heterozygosity for novel splice site mutations in the BPAG2/COL17A1 gene underlies generalized atrophic benign epidermolysis bullosa. Pulkkinen L, Marinkovich MP, Tran HT, Lin L, Herron GS, Uitto J. J Invest Dermatol. 1999; 113 (6): 1114-8
• Gene therapy for a lethal genetic blistering disease: a status report. Bauer EA, Herron GS, Marinkovich MP, Khavari PA, Lane AT. Trans Am Clin Climatol Assoc. 1999: 110 86-92
• Melanocytes adhere to and synthesize laminin-5 in vitro. Scott GA, Cassidy L, Tran H, Rao SK, Marinkovich MP. Exp Dermatol. 1999; 8 (3): 212-21
• NC1 domain of type VII collagen binds to the beta3 chain of laminin 5 via a unique subdomain within the fibronectin-like repeats. Chen M, Marinkovich MP, Jones JC, O'Toole EA, Li YY, Woodley DT. J Invest Dermatol. 1999; 112 (2): 177-83
• Novel feline autoimmune blistering disease resembling bullous pemphigoid in humans: IgG autoantibodies target the NC16A ectodomain of type XVII collagen (BP180/BPAG2). Olivry T, Chan LS, Xu L, Chace P, Dunston SM, Fahey M, Marinkovich MP. Vet Pathol. 1999; 36 (4): 328-35
• Reduced anchoring fibril formation and collagen VII immunoreactivity in feline dystrophic epidermolysis bullosa. Olivry T, Dunston SM, Marinkovich MP. Vet Pathol. 1999; 36 (6): 616-8
• Update on inherited bullous dermatoses. Marinkovich MP, Dermatol Clin. 1999; 17 (3): 473-85, vii
• Hypoxia increases human keratinocyte motility on connective tissue. O'Toole EA, Marinkovich MP, Peavey CL, Amieva MR, Furthmayr H, Mustoe TA, Woodley DT. J Clin Invest. 1997; 100 (11): 2881-91
• Immunodissection of the connective tissue matrix in human skin. Keene DR, Marinkovich MP, Sakai LY. Microsc Res Tech. 1997; 38 (4): 394-406
• Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin. Chen M, Marinkovich MP, Veis A, Cai X, Rao CN, O'Toole EA, Woodley DT. J Biol Chem. 1997; 272 (23): 14516-22
• LAD-1 is absent in a subset of junctional epidermolysis bullosa patients. Marinkovich MP, Tran HH, Rao SK, Giudice GJ, Balding S, Jonkman MF, Pas HH, McGuire JS, Herron GS, Bruckner-Tuderman L. J Invest Dermatol. 1997; 109 (3): 356-9
• Laminin-5 inhibits human keratinocyte migration. O'Toole EA, Marinkovich MP, Hoeffler WK, Furthmayr H, Woodley DT. Exp Cell Res. 1997; 233 (2): 330-9
• Laminin-6 and laminin-5 are recognized by autoantibodies in a subset of cicatricial pemphigoid. Chan LS, Majmudar AA, Tran HH, Meier F, Schaumburg-Lever G, Chen M, Anhalt G, Woodley DT, Marinkovich MP. J Invest Dermatol. 1997; 108 (6): 848-53
• Self-assembly of laminin isoforms. Cheng YS, Champliaud MF, Burgeson RE, Marinkovich MP, Yurchenco PD. J Biol Chem. 1997; 272 (50): 31525-32
• A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone. Zillikens D, Kawahara Y, Ishiko A, Shimizu H, Mayer J, Rank CV, Liu Z, Giudice GJ, Tran HH, Marinkovich MP, Brocker EB, Hashimoto T. J Invest Dermatol. 1996; 106 (6): 1333-8
• A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone. Zillikens D, Kawahara Y, Ishiko A, Shimizu H, Mayer J, Rank CV, Liu Z, Giudice GJ, Tran HH, Marinkovich MP, Bröcker EB, Hashimoto T. J Invest Dermatol. 1996; 106 (3): 465-70
• LAD-1, the linear IgA bullous dermatosis autoantigen, is a novel 120-kDa anchoring filament protein synthesized by epidermal cells. Marinkovich MP, Taylor TB, Keene DR, Burgeson RE, Zone JJ. J Invest Dermatol. 1996; 106 (4): 734-8
• A newly identified 105-kD lower lamina lucida autoantigen is an acidic protein distinct from the 105-kD gamma 2 chain of laminin-5. Chan LS, Wang XS, Lapiere JC, Marinkovich MP, Jones JC, Woodley DT. J Invest Dermatol. 1995; 105 (1): 75-9
• Anti-basement membrane autoantibodies in patients with anti-epiligrin cicatricial pemphigoid bind the alpha subunit of laminin 5. Kirtschig G, Marinkovich MP, Burgeson RE, Yancey KB. J Invest Dermatol. 1995; 105 (4): 543-8
• Necrolytic migratory erythema without glucagonoma in patients with liver disease. Marinkovich MP, Botella R, Datloff J, Sangueza OP. J Am Acad Dermatol. 1995; 32 (4): 604-9
• Prenatal diagnosis of Herlitz junctional epidermolysis bullosa by amniocentesis. Marinkovich MP, Meneguzzi G, Burgeson RE, Blanchet-Bardon C, Holbrook KA, Smith LT, Christiano AM, Ortonne JP. Prenat Diagn. 1995; 15 (11): 1027-34
• Basement membrane proteins kalinin and nicein are structurally and immunologically identical. Marinkovich MP, Verrando P, Keene DR, Meneguzzi G, Lunstrum GP, Ortonne JP, Burgeson RE. Lab Invest. 1993; 69 (3): 295-9
• Cellular origin of the dermal-epidermal basement membrane. Marinkovich MP, Keene DR, Rimberg CS, Burgeson RE. Dev Dyn. 1993; 197 (4): 255-67
• The molecular genetics of basement membrane diseases. Marinkovich MP, Arch Dermatol. 1993; 129 (12): 1557-65
• Identification and partial purification of a large, variant form of type XII collagen. Lunstrum GP, McDonough AM, Marinkovich MP, Keene DR, Morris NP, Burgeson RE. J Biol Chem. 1992; 267 (28): 20087-92
• Kalinin is abnormally expressed in epithelial basement membranes of Herlitz's junctional epidermolysis bullosa patients. Meneguzzi G, Marinkovich MP, Aberdam D, Pisani A, Burgeson R, Ortonne JP. Exp Dermatol. 1992; 1 (5): 221-9
• The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor. Marinkovich MP, Lunstrum GP, Burgeson RE. J Biol Chem. 1992; 267 (25): 17900-6
• The dermal-epidermal junction of human skin contains a novel laminin variant. Marinkovich MP, Lunstrum GP, Keene DR, Burgeson RE. J Cell Biol. 1992; 119 (3): 695-703
• Synthesis of calelectrins and calpactin I during cytochalasin mediated cell spreading inhibition. Hom YK, Marinkovich MP, Lozano JJ, Rocha V. Cell Calcium. 1989; 10 (3): 135-44
• Basal lamina inhibition suppresses synthesis of calcium-dependent proteins associated with mammary epithelial cell spreading. Rocha V, Hom YK, Marinkovich MP. Exp Cell Res. 1986; 165 (2): 450-60
• Collagen synthesis and deposition during mammary epithelial cell spreading on collagen gels. Marinkovich MP, Rocha V. J Cell Physiol. 1986; 128 (1): 61-70