Anson Lowe

Publications

• CITED2 is a novel direct effector of peroxisome proliferator-activated receptor γ in suppressing hepatocellular carcinoma cell growth. Cheung KF, Zhao J, Hao Y, Li X, Lowe AW, Cheng AS, Sung JJ, Yu J. Cancer. 2013; 119 (6): 1217-26
• Loss of anterior gradient 2 (Agr2) expression results in hyperplasia and defective lineage maturation in the murine stomach. Gupta A, Wodziak D, Tun M, Bouley DM, Lowe AW. J Biol Chem. 2013; 288 (6): 4321-33
• AGR2 gene function requires a unique endoplasmic reticulum localization motif. Gupta A, Dong A, Lowe AW. J Biol Chem. 2012; 287 (7): 4773-82
• Diagnostic accuracy of cyst fluid amphiregulin in pancreatic cysts. Tun MT, Pai RK, Kwok S, Dong A, Gupta A, Visser BC, Norton JA, Poultsides GA, Banerjee S, Van Dam J, Chen AM, Friedland S, Scott BA, Verma R, Lowe AW, Park WG. BMC Gastroenterol. 2012: 12 15
• Immunohistochemical panel for distinguishing esophageal adenocarcinoma from squamous cell carcinoma: a combination of p63, cytokeratin 5/6, MUC5AC, and anterior gradient homolog 2 allows optimal subtyping. DiMaio MA, Kwok S, Montgomery KD, Lowe AW, Pai RK. Hum Pathol. 2012; 43 (11): 1799-807
• PDX1 regulation of FABP1 and novel target genes in human intestinal epithelial Caco-2 cells. Chen C, Fang R, Chou LC, Lowe AW, Sibley E. Biochem Biophys Res Commun. 2012; 423 (1): 183-7
• The human adenocarcinoma-associated gene, AGR2, induces expression of amphiregulin through Hippo pathway co-activator YAP1 activation. Dong A, Gupta A, Pai RK, Tun M, Lowe AW. J Biol Chem. 2011; 286 (20): 18301-10
• Endoscopic evaluation of esophago-gastro-jejunostomy in rat model of Barrett's esophagus. Lu S, Lowe AW, Triadafilopoulos G, Hsiung PL, Hao Y, Crawford JM, Wang TD. Dis Esophagus. 2009; 22 (4): 323-30
• Painless jaundice and bilaterally enlarged sub-mandibular glands in an elderly man. Park WG, Pai R, Ro K, Lowe AW. Dig Dis Sci. 2009; 54 (3): 488-90
• The pancreatic zymogen granule membrane protein, GP2, binds Escherichia coli Type 1 fimbriae. Yu S, Lowe AW. BMC Gastroenterol. 2009: 9 58
• Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. Hase K, Kawano K, Nochi T, Pontes GS, Fukuda S, Ebisawa M, Kadokura K, Tobe T, Fujimura Y, Kawano S, Yabashi A, Waguri S, Nakato G, Kimura S, Murakami T, Iimura M, Hamura K, Fukuoka S, Lowe AW, Itoh K, Kiyono H, Ohno H. Nature. 2009; 462 (7270): 226-30
• Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy. Hsiung PL, Hsiung PL, Hardy J, Friedland S, Soetikno R, Du CB, Wu AP, Sahbaie P, Crawford JM, Lowe AW, Contag CH, Wang TD. Nat Med. 2008; 14 (4): 454-8
• The adenocarcinoma-associated antigen, AGR2, promotes tumor growth, cell migration, and cellular transformation. Wang Z, Hao Y, Lowe AW. Cancer Res. 2008; 68 (2): 492-7
• The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha-ras co-transfection. Einav S, Sklan EH, Moon HM, Gehrig E, Liu P, Hao Y, Lowe AW, Glenn JS. Hepatology. 2008; 47 (3): 827-35
• Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure. Hao Y, Sood S, Triadafilopoulos G, Kim JH, Wang Z, Sahbaie P, Omary MB, Lowe AW. BMC Gastroenterol. 2007: 7 24
• Gene expression patterns in pancreatic tumors, cells and tissues. Lowe AW, Olsen M, Hao Y, Lee SP, Taek Lee K, Chen X, van de Rijn M, Brown PO. PLoS One. 2007; 2 (3): e323
• The pancreatic stellate cell: a star on the rise in pancreatic diseases. Omary MB, Lugea A, Lowe AW, Pandol SJ. J Clin Invest. 2007; 117 (1): 50-9
• Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma. Hao Y, Triadafilopoulos G, Sahbaie P, Young HS, Omary MB, Lowe AW. Gastroenterology. 2006; 131 (3): 925-33
• The genome is now accessible to the endoscopist. Lowe AW, Gastrointest Endosc. 2006; 64 (1): 27-8
• Absence of the major zymogen granule membrane protein, GP2, does not affect pancreatic morphology or secretion. Yu S, Michie SA, Lowe AW. J Biol Chem. 2004; 279 (48): 50274-9
• Determination of plasma glycoprotein 2 levels in patients with pancreatic disease. Hao Y, Wang J, Feng N, Lowe AW. Arch Pathol Lab Med. 2004; 128 (6): 668-74
• Effects of GP2 expression on secretion and endocytosis in pancreatic AR4-2J cells. Yu S, Hao Y, Lowe AW. Biochem Biophys Res Commun. 2004; 322 (1): 320-5
• Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. Iacobuzio-Donahue CA, Maitra A, Olsen M, Lowe AW, van Heek NT, Rosty C, Walter K, Sato N, Parker A, Ashfaq R, Jaffee E, Ryu B, Jones J, Eshleman JR, Yeo CJ, Cameron JL, Kern SE, Hruban RH, Brown PO, Goggins M. Am J Pathol. 2003; 162 (4): 1151-62
• Processing of the major pancreatic zymogen granule membrane protein, GP2. Fritz BA, Poppel CS, Fei MW, Lowe AW. Pancreas. 2002; 24 (4): 336-43
• Effects of keratin filament disruption on exocrine pancreas-stimulated secretion and susceptibility to injury. Toivola DM, Ku NO, Ghori N, Lowe AW, Michie SA, Omary MB. Exp Cell Res. 2000; 255 (2): 156-70
• Characterization of an alternatively spliced isoform of rat vesicle associated membrane protein-2 (VAMP-2). Mandic R, Lowe AW. FEBS Lett. 1999; 451 (2): 209-13
• Tissue-specific alternative RNA splicing of rat vesicle-associated membrane protein-1 (VAMP-1). Mandic R, Trimble WS, Lowe AW. Gene. 1997; 199 (1-2): 173-9
• Polarized GP2 secretion in MDCK cells via GPI targeting and apical membrane-restricted proteolysis. Fritz BA, Lowe AW. Am J Physiol. 1996; 270 (1 Pt 1): G176-83
• Sequence of the cDNA encoding human GP-2, the major membrane protein in the secretory granule of the exocrine pancreas. Wong SM, Lowe AW. Gene. 1996; 171 (2): 311-2
• Hierarchy of mechanisms involved in generating Na/K-ATPase polarity in MDCK epithelial cells. Mays RW, Siemers KA, Fritz BA, Lowe AW, van Meer G, Nelson WJ. J Cell Biol. 1995; 130 (5): 1105-15
• Apical plasma membrane proteins are not obligatorily stored in secretory granules in exocrine cells. Colomer V, Rindler MJ, Lowe AW. J Cell Sci. 1994: 107 ( Pt 8) 2271-7
• Identification of a vesicle-associated membrane protein (VAMP)-like membrane protein in zymogen granules of the rat exocrine pancreas. Braun JE, Fritz BA, Wong SM, Lowe AW. J Biol Chem. 1994; 269 (7): 5328-35
• The level of the zymogen granule protein GP2 is elevated in a rat model for acute pancreatitis. Lowe AW, Luthen RE, Wong SM, Grendell JH. Gastroenterology. 1994; 107 (6): 1819-27
• Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents. Wagner JA, McDonald TV, Nghiem PT, Lowe AW, Schulman H, Gruenert DC, Stryer L, Gardner P. Proc Natl Acad Sci U S A. 1992; 89 (15): 6785-9