Gilbert Chu
Publications
- Cooperative assembly of a protein-DNA filament for nonhomologous end joining. J Biol Chem. 2013
- Local false discovery rate facilitates comparison of different microarray experiments. Nucleic Acids Res. 2009; (22): 7483-97
- Here comes the sun: recognition of UV-damaged DNA. Cell. 2008; (7): 1172-4
- Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends. Proc Natl Acad Sci U S A. 2007; (19): 7851-6
- Processing of DNA for nonhomologous end-joining is controlled by kinase activity and XRCC4/ligase IV. J Biol Chem. 2007; (16): 11950-9
- Processing of DNA for nonhomologous end-joining by cell-free extract. EMBO J. 2005; (4): 849-60
- Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Proc Natl Acad Sci U S A. 2004; (17): 6635-40
- Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A. 2001; (9): 5116-21
- Electrophoretic mobility shift assays for protein-DNA complexes involved in DNA repair. Methods Mol Biol. 2012: 53-78
- An information theoretic, microfluidic-based single cell analysis permits identification of subpopulations among putatively homogeneous stem cells. PLoS One. 2011; (6): e21211
- Assays for nonhomologous end joining in extracts. Methods Enzymol. 2006: 430-44
- Portrait of transcriptional responses to ultraviolet and ionizing radiation in human cells. Nucleic Acids Res. 2004; (16): 4786-803
- Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc Natl Acad Sci U S A. 2002; (10): 6567-72
- Synapsis of DNA ends by DNA-dependent protein kinase. EMBO J. 2002; (12): 3192-200
- Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein. DNA Repair (Amst). 2002; (8): 601-16
- p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice. Mol Cell Biol. 2002; (10): 3247-54
- Activation of DNA-dependent protein kinase by single-stranded DNA ends. J Biol Chem. 2000; (3): 1541-50
- Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis. Mol Cell. 2000; (4): 737-44
- Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proc Natl Acad Sci U S A. 1999; (2): 424-8
- Structure of DNA-dependent protein kinase: implications for its regulation by DNA. EMBO J. 1999; (5): 1114-23
- The use of electrophoretic mobility shift assays to study DNA repair. Methods Mol Biol. 1999: 103-20
- DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proc Natl Acad Sci U S A. 1998; (2): 525-30
- Failure of hairpin-ended and nicked DNA To activate DNA-dependent protein kinase: implications for V(D)J recombination. Mol Cell Biol. 1998; (11): 6853-8
- p48 Activates a UV-damaged-DNA binding factor and is defective in xeroderma pigmentosum group E cells that lack binding activity. Mol Cell Biol. 1998; (7): 4391-9
- DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage. Cancer Res. 1997; (1): 68-74
- Double strand break repair. J Biol Chem. 1997; (39): 24097-100
- The end-joining reaction in V(D)J recombination. Semin Immunol. 1997; (3): 189-97
- Isolation of a cDNA encoding a UV-damaged DNA binding factor defective in xeroderma pigmentosum group E cells. Mutat Res. 1996; (1): 105-17
- Role of the Ku autoantigen in V(D)J recombination and double-strand break repair. Curr Top Microbiol Immunol. 1996: 113-32
- Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy: do the genes explain the diseases? Trends Genet. 1996; (5): 187-92
- A DNA end-binding factor involved in double-strand break repair and V(D)J recombination. Mol Cell Biol. 1994; (7): 4741-8
- A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiae. Mol Cell Biol. 1994; (12): 8071-7
- Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair. J Biol Chem. 1994; (2): 787-90
- Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks. Proc Natl Acad Sci U S A. 1994; (16): 7623-7
- Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science. 1994; (5183): 288-91
- Xeroderma pigmentosum group E binding factor recognizes a broad spectrum of DNA damage. Mutat Res. 1994; (1): 89-102
- Massive cisplatin overdose by accidental substitution for carboplatin. Toxicity and management. Cancer. 1993; (12): 3707-14
- Purification and characterization of a human protein that binds to damaged DNA. Biochemistry. 1993; (6): 1657-66
- Bag model for DNA migration during pulsed-field electrophoresis. Proc Natl Acad Sci U S A. 1991; (24): 11071-5
- Pulsed-field electrophoresis of megabase-sized DNA. Mol Cell Biol. 1991; (6): 3348-54
- Separation of large DNA by a variable-angle contour-clamped homogeneous electric field apparatus. Anal Biochem. 1991; (2): 439-46
- Cisplatin-resistant cells express increased levels of a factor that recognizes damaged DNA. Proc Natl Acad Sci U S A. 1990; (9): 3324-7
- Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA. Science. 1988; (4878): 564-7
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