Teresa Wang

Publications

• Replication-compromised cells require the mitotic checkpoint to prevent tetraploidization. Zhang Z, Arora S, Zhou Y, Cherry A, Wang TS. Chromosoma. 2011; 120 (1): 73-82
• Rad3-dependent phosphorylation of the checkpoint clamp regulates repair-pathway choice. Kai M, Furuya K, Paderi F, Carr AM, Wang TS. Nat Cell Biol. 2007; 9 (6): 691-7
• Rad4TopBP1 associates with Srr2, an Spc1 MAPK-regulated protein, in response to environmental stress. Taricani L, Wang TS. J Biol Chem. 2007; 282 (12): 8793-800
• Methods for studying mutagenesis and checkpoints in Schizosaccharomyces pombe. Kai M, Taricani L, Wang TS. Methods Enzymol. 2006: 409 183-94
• Rad4TopBP1, a scaffold protein, plays separate roles in DNA damage and replication checkpoints and DNA replication. Taricani L, Wang TS. Mol Biol Cell. 2006; 17 (8): 3456-68
• Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Kai M, Boddy MN, Russell P, Wang TS. Genes Dev. 2005; 19 (8): 919-32
• A coordinated temporal interplay of nucleosome reorganization factor, sister chromatin cohesion factor, and DNA polymerase alpha facilitates DNA replication. Zhou Y, Wang TS. Mol Cell Biol. 2004; 24 (21): 9568-79
• The B-subunit of DNA polymerase alpha-primase associates with the origin recognition complex for initiation of DNA replication. Uchiyama M, Wang TS. Mol Cell Biol. 2004; 24 (17): 7419-34
• Checkpoint activation regulates mutagenic translesion synthesis. Kai M, Wang TS. Genes Dev. 2003; 17 (1): 64-76
• Checkpoint responses to replication stalling: inducing tolerance and preventing mutagenesis. Kai M, Wang TS. Mutat Res. 2003; 532 (1-2): 59-73
• Genomic instability induced by mutations in Saccharomyces cerevisiae POL1. Gutiérrez PJ, Wang TS. Genetics. 2003; 165 (1): 65-81
• Replication proteins influence the maintenance of telomere length and telomerase protein stability. Dahlén M, Sunnerhagen P, Wang TS. Mol Cell Biol. 2003; 23 (9): 3031-42
• Fission yeast Rad17 associates with chromatin in response to aberrant genomic structures. Kai M, Tanaka H, Wang TS. Mol Cell Biol. 2001; 21 (10): 3289-301
• Role of fission yeast primase catalytic subunit in the replication checkpoint. Griffiths DJ, Liu VF, Nurse P, Wang TS. Mol Biol Cell. 2001; 12 (1): 115-28
• A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints. Griffiths D, Uchiyama M, Nurse P, Wang TS. J Cell Sci. 2000: 113 ( Pt 6) 1075-88
• Analysis of fission yeast primase defines the checkpoint responses to aberrant S phase initiation. Tan S, Wang TS. Mol Cell Biol. 2000; 20 (21): 7853-66
• Human papillomavirus DNA replication. Interactions between the viral E1 protein and two subunits of human dna polymerase alpha/primase. Conger KL, Liu JS, Kuo SR, Chow LT, Wang TS. J Biol Chem. 1999; 274 (5): 2696-705
• Mutator phenotype induced by aberrant replication. Liu VF, Bhaumik D, Wang TS. Mol Cell Biol. 1999; 19 (2): 1126-35
• Schizosaccharomyces pombe replication and repair proteins: proliferating cell nuclear antigen (PCNA). Arroyo MP, Wang TS. Methods. 1999; 18 (3): 335-48, 324
• Mutant PCNA alleles are associated with cdc phenotypes and sensitivity to DNA damage in fission yeast. Arroyo MP, Wang TS. Mol Gen Genet. 1998; 257 (5): 505-18
• Mutational effect of fission yeast polalpha on cell cycle events. Bhaumik D, Wang TS. Mol Biol Cell. 1998; 9 (8): 2107-23
• A novel mutant allele of Schizosaccharomyces pombe rad26 defective in monitoring S-phase progression to prevent premature mitosis. Uchiyama M, Galli I, Griffiths DJ, Wang TS. Mol Cell Biol. 1997; 17 (6): 3103-15
• DNA replication and order of cell cycle events: a role for protein isoprenylation? Galli I, Uchiyama M, Wang TS. Biol Chem. 1997; 378 (9): 963-73
• Schizosaccharomyces pombe proliferating cell nuclear antigen mutations affect DNA polymerase delta processivity. Arroyo MP, Downey KM, So AG, Wang TS. J Biol Chem. 1996; 271 (27): 15971-80
• Interaction of herpes simplex virus 1 origin-binding protein with DNA polymerase alpha. Lee SS, Dong Q, Wang TS, Lehman IR. Proc Natl Acad Sci U S A. 1995; 92 (17): 7882-6
• Mutational studies of human DNA polymerase alpha. Lysine 950 in the third most conserved region of alpha-like DNA polymerases is involved in binding the deoxynucleoside triphosphate. Dong Q, Wang TS. J Biol Chem. 1995; 270 (37): 21563-70
• Purification of mammalian DNA polymerases: DNA polymerase alpha. Wang TS, Copeland WC, Rogge L, Dong Q. Methods Enzymol. 1995: 262 77-84
• Rationale for mutagenesis of DNA polymerase active sites: DNA polymerase alpha. Copeland WC, Dong Q, Wang TS. Methods Enzymol. 1995: 262 294-303
• Studies of Schizosaccharomyces pombe DNA polymerase alpha at different stages of the cell cycle. Park H, Davis R, Wang TS. Nucleic Acids Res. 1995; 23 (21): 4337-44
• Down-regulation of genes encoding DNA replication proteins during cell cycle exit. Moore AL, Wang TS. Cell Growth Differ. 1994; 5 (5): 485-94
• Cell cycle expression of two replicative DNA polymerases alpha and delta from Schizosaccharomyces pombe. Park H, Francesconi S, Wang TS. Mol Biol Cell. 1993; 4 (2): 145-57
• Enzymatic characterization of the individual mammalian primase subunits reveals a biphasic mechanism for initiation of DNA replication. Copeland WC, Wang TS. J Biol Chem. 1993; 268 (35): 26179-89
• Fidelity studies of the human DNA polymerase alpha. The most conserved region among alpha-like DNA polymerases is responsible for metal-induced infidelity in DNA synthesis. Copeland WC, Lam NK, Wang TS. J Biol Chem. 1993; 268 (15): 11041-9
• Fission yeast with DNA polymerase delta temperature-sensitive alleles exhibits cell division cycle phenotype. Francesconi S, Park H, Wang TS. Nucleic Acids Res. 1993; 21 (16): 3821-8
• In vivo species specificity of DNA polymerase alpha. Francesconi S, Copeland WC, Wang TS. Mol Gen Genet. 1993; 241 (3-4): 457-66
• Initiation of simian virus 40 DNA replication requires the interaction of a specific domain of human DNA polymerase alpha with large T antigen. Dornreiter I, Copeland WC, Wang TS. Mol Cell Biol. 1993; 13 (2): 809-20
• Mutational analysis of the human DNA polymerase alpha. The most conserved region in alpha-like DNA polymerases is involved in metal-specific catalysis. Copeland WC, Wang TS. J Biol Chem. 1993; 268 (15): 11028-40
• Mutational studies of human DNA polymerase alpha. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis. Dong Q, Copeland WC, Wang TS. J Biol Chem. 1993; 268 (32): 24163-74
• Mutational studies of human DNA polymerase alpha. Serine 867 in the second most conserved region among alpha-like DNA polymerases is involved in primer binding and mispair primer extension. Dong Q, Copeland WC, Wang TS. J Biol Chem. 1993; 268 (32): 24175-82
• Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. Copeland WC, Chen MS, Wang TS. J Biol Chem. 1992; 267 (30): 21459-64
• Protein affinity chromatography reveals cell cycle dependent association of cellular factors with human DNA polymerase alpha. Rogge L, Wang TS. Chromosoma. 1992; 102 (1 Suppl): S114-20
• Catalytic subunit of human DNA polymerase alpha overproduced from baculovirus-infected insect cells. Structural and enzymological characterization. Copeland WC, Wang TS. J Biol Chem. 1991; 266 (33): 22739-48
• Cell cycle-dependent phosphorylation of human DNA polymerase alpha. Nasheuer HP, Moore A, Wahl AF, Wang TS. J Biol Chem. 1991; 266 (12): 7893-903
• Eukaryotic DNA polymerases. Wang TS, Annu Rev Biochem. 1991: 60 513-52
• Human DNA polymerase alpha gene: sequences controlling expression in cycling and serum-stimulated cells. Pearson BE, Nasheuer HP, Wang TS. Mol Cell Biol. 1991; 11 (4): 2081-95
• Human DNA polymerase alpha catalytic polypeptide binds ConA and RCA and contains a specific labile site in the N-terminus. Hsi KL, Copeland WC, Wang TS. Nucleic Acids Res. 1990; 18 (21): 6231-7
• DNA polymerases alpha and delta are immunologically and structurally distinct. Wong SW, Syvaoja J, Tan CK, Downey KM, So AG, Linn S, Wang TS. J Biol Chem. 1989; 264 (10): 5924-8
• Human DNA polymerase alpha: predicted functional domains and relationships with viral DNA polymerases. Wang TS, Wong SW, Korn D. FASEB J. 1989; 3 (1): 14-21
• Gene expression of human DNA polymerase alpha during cell proliferation and the cell cycle. Wahl AF, Geis AM, Spain BH, Wong SW, Korn D, Wang TS. Mol Cell Biol. 1988; 8 (11): 5016-25
• Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases. Wong SW, Wahl AF, Yuan PM, Arai N, Pearson BE, Arai K, Korn D, Hunkapiller MW, Wang TS. EMBO J. 1988; 7 (1): 37-47
• The evolutionary conservation of DNA polymerase alpha. Miller MA, Korn D, Wang TS. Nucleic Acids Res. 1988; 16 (16): 7961-73