Christopher H. Contag
Publications
- Heme oxygenase-1 deletion affects stress erythropoiesis. PLoS One. 2011; (5): e20634
- Synergistic antitumor effects of immune cell-viral biotherapy. Science. 2006; (5768): 1780-4
- Extracellular replication of Listeria monocytogenes in the murine gall bladder. Science. 2004; (5659): 851-3
- MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature. 2004; (7012): 1112-7
- Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A. 2004; (1): 221-6
- Visualizing gene expression in living mammals using a bioluminescent reporter. Photochem Photobiol. 1997; (4): 523-31
- Photonic detection of bacterial pathogens in living hosts. Mol Microbiol. 1995; (4): 593-603
- Advancing the translation of optical imaging agents for clinical imaging. Biomed Opt Express. 2013; (1): 160-70
- Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. J Control Release. 2013; (3): 211-9
- Comparing an optical parametric oscillator (OPO) as a viable alternative for mid-infrared tissue ablation with a free electron laser (FEL). Lasers Med Sci. 2012; (6): 1213-23
- Development of B cells and erythrocytes is specifically impaired by the drug celastrol in mice. PLoS One. 2012; (4): e35733
- Femtosecond plasma mediated laser ablation has advantages over mechanical osteotomy of cranial bone. Lasers Surg Med. 2012; (10): 805-14
- Identification of cell surface targets through meta-analysis of microarray data. Neoplasia. 2012; (7): 666-9
- In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract. J Biomed Opt. 2012; (2): 021102
- Infection of pregnant mice with Listeria monocytogenes induces fetal bradycardia. Pediatr Res. 2012; (5): 539-45
- Microscopic Delineation of Medulloblastoma Margins in a Transgenic Mouse Model Using a Topically Applied VEGFR-1 Probe. Transl Oncol. 2012; (6): 408-14
- Efficacy of antimicrobial peptoids against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2011; (6): 3058-62
- Image-guided genomic analysis of tissue response to laser-induced thermal stress. J Biomed Opt. 2011; (5): 058001
- In vivo bioluminescence imaging of inducible nitric oxide synthase gene expression in vascular inflammation. Mol Imaging Biol. 2011; (6): 1061-6
- In vivo imaging of human and mouse skin with a handheld dual-axis confocal fluorescence microscope. J Invest Dermatol. 2011; (5): 1061-6
- In vivo micro-image mosaicing. IEEE Trans Biomed Eng. 2011; (1): 159-71
- Molecular imaging of inflammation and carcinogenesis. Cancer Prev Res (Phila). 2011; (10): 1523-6
- Non-damaging retinal phototherapy: dynamic range of heat shock protein expression. Invest Ophthalmol Vis Sci. 2011; (3): 1780-7
- Pulse duration determines levels of Hsp70 induction in tissues following laser irradiation. J Biomed Opt. 2011; (7): 078002
- Assessing delivery and quantifying efficacy of small interfering ribonucleic acid therapeutics in the skin using a dual-axis confocal microscope. J Biomed Opt. 2010 May-Jun; (3): 036027
- Micromirror-scanned dual-axis confocal microscope utilizing a gradient-index relay lens for image guidance during brain surgery. J Biomed Opt. 2010 Mar-Apr; (2): 026029
- Biodegradable nanoparticles with sustained release of functional siRNA in skin. J Pharm Sci. 2010; (10): 4261-6
- Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Proc Natl Acad Sci U S A. 2010; (42): 18115-20
- Definition of an enhanced immune cell therapy in mice that can target stem-like lymphoma cells. Cancer Res. 2010; (23): 9837-45
- Fiber-optic probes enable cancer detection with FTIR spectroscopy. Trends Biotechnol. 2010; (6): 317-23
- Guided by the light: visualizing biomolecular processes in living animals with bioluminescence. Curr Opin Chem Biol. 2010; (1): 80-9
- IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy. Cancer Immunol Immunother. 2010; (9): 1325-34
- Increased interstitial pressure improves nucleic acid delivery to skin enabling a comparative analysis of constitutive promoters. Gene Ther. 2010; (10): 1270-8
- Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy. Gene Ther. 2010; (7): 827-38
- Longitudinal, noninvasive imaging of T-cell effector function and proliferation in living subjects. Cancer Res. 2010; (24): 10141-9
- Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice. Am J Pathol. 2010; (2): 926-38
- Nanoparticle formation of organic compounds with retained biological activity. J Pharm Sci. 2010; (6): 2750-5
- Role of nitric oxide in Salmonella typhimurium-mediated cancer cell killing. BMC Cancer. 2010: 146
- Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD). Mol Ther. 2010; (9): 1667-74
- Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery after myocardial infarction. Circ Cardiovasc Imaging. 2010; (1): 77-85
- Laser-induced disruption of systemically administered liposomes for targeted drug delivery. J Biomed Opt. 2009 Jul-Aug; (4): 044009
- Use of an endoscope-compatible probe to detect colonic dysplasia with Fourier transform infrared spectroscopy. J Biomed Opt. 2009 Jul-Aug; (4): 044006
- Foci of Listeria monocytogenes persist in the bone marrow. Dis Model Mech. 2009 Jan-Feb; (1-2): 39-46
- A general method for conditional regulation of protein stability in living animals. Cold Spring Harb Protoc. 2009; (3): pdb.prot5173
- CNOB/ChrR6, a new prodrug enzyme cancer chemotherapy. Mol Cancer Ther. 2009; (2): 333-41
- Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart. Transplantation. 2009; (5): 642-52
- FTIR microspectroscopy for improved prostate cancer diagnosis. Trends Biotechnol. 2009; (12): 661-3
- Fibered confocal microscopy of bladder tumors: an ex vivo study. J Endourol. 2009; (2): 197-201
- Lymphoid-tissue-specific homing of bone-marrow-derived dendritic cells. Blood. 2009; (26): 6638-47
- Quantifying cell-surface biomarker expression in thick tissues with ratiometric three-dimensional microscopy. Biophys J. 2009; (6): 2405-14
- Stem cell-mediated accelerated bone healing observed with in vivo molecular and small animal imaging technologies in a model of skeletal injury. J Orthop Res. 2009; (3): 295-302
- The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals. J Immunol. 2009; (12): 7558-68
- Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. Stem Cells. 2009; (7): 1548-58
- siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model. Gene Ther. 2009; (8): 963-72
- Efficient rejection of scattered light enables deep optical sectioning in turbid media with low-numerical-aperture optics in a dual-axis confocal architecture. J Biomed Opt. 2008 May-Jun; (3): 034020
- In vivo analysis of heat-shock-protein-70 induction following pulsed laser irradiation in a transgenic reporter mouse. J Biomed Opt. 2008 May-Jun; (3): 030501
- Chemical control of protein stability and function in living mice. Nat Med. 2008; (10): 1123-7
- Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation. 2008; (14 Suppl): S121-9
- Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy. Nat Med. 2008; (4): 454-8
- Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. Blood. 2008; (12): 4494-502
- Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters. Proc Natl Acad Sci U S A. 2008; (34): 12128-33
- Prevention of acute graft-versus-host disease by blocking T-cell entry to secondary lymphoid organs. Blood. 2008; (5): 2919-28
- Regulation of maternal and fetal hemodynamics by heme oxygenase in mice. Biol Reprod. 2008; (4): 744-51
- Sustained release of drugs dispersed in polymer nanoparticles. Angew Chem Int Ed Engl. 2008; (41): 7880-2
- Three-dimensional in vivo imaging by a handheld dual-axes confocal microscope. Opt Express. 2008; (10): 7224-32
- Accelerated bone repair after plasma laser corticotomies. Ann Surg. 2007; (1): 140-50
- Combining immune cell and viral therapy for the treatment of cancer. Cell Mol Life Sci. 2007; (12): 1449-51
- Delivery and inhibition of reporter genes by small interfering RNAs in a mouse skin model. J Invest Dermatol. 2007; (11): 2577-84
- Design and evaluation of a variable aperture collimator for conformal radiotherapy of small animals using a microCT scanner. Med Phys. 2007; (11): 4359-67
- Detection of endogenous biomolecules in Barrett's esophagus by Fourier transform infrared spectroscopy. Proc Natl Acad Sci U S A. 2007; (40): 15864-9
- Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host disease. Blood. 2007; (5): 2225-33
- Functional imaging of colonic mucosa with a fibered confocal microscope for real-time in vivo pathology. Clin Gastroenterol Hepatol. 2007; (11): 1300-5
- In vivo dynamics of regulatory T-cell trafficking and survival predict effective strategies to control graft-versus-host disease following allogeneic transplantation. Blood. 2007; (6): 2649-56
- In vivo pathology: seeing with molecular specificity and cellular resolution in the living body. Annu Rev Pathol. 2007: 277-305
- Methods for imaging cell fates in hematopoiesis. Methods Mol Med. 2007: 17-34
- Miniature near-infrared dual-axes confocal microscope utilizing a two-dimensional microelectromechanical systems scanner. Opt Lett. 2007; (3): 256-8
- Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells. 2007; (10): 2677-84
- Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice. Proc Natl Acad Sci U S A. 2007; (25): 10340-5
- The potential Salmonella aroA- vaccine strain is safe and effective in young BALB/c mice. Neonatology. 2007; (2): 114-20
- Dual-axes confocal reflectance microscope for distinguishing colonic neoplasia. J Biomed Opt. 2006 Sep-Oct; (5): 054019
- Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation. Bioconjug Chem. 2006 May-Jun; (3): 787-96
- Cellular tolerance to pulsed hyperthermia. Phys Rev E Stat Nonlin Soft Matter Phys. 2006; (1 Pt 1): 011915
- Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study. Clin Cancer Res. 2006; (6): 1859-67
- Expression and regulation of heme oxygenase isozymes in the developing mouse cortex. Pediatr Res. 2006; (5): 518-23
- In vivo imaging using bioluminescence: a tool for probing graft-versus-host disease. Nat Rev Immunol. 2006; (6): 484-90
- Induced biliary excretion of Listeria monocytogenes. Infect Immun. 2006; (3): 1819-27
- Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production. Blood. 2006; (1): 390-9
- Luciferin derivatives for enhanced in vitro and in vivo bioluminescence assays. Biochemistry. 2006; (37): 11103-12
- Molecular imaging using visible light to reveal biological changes in the brain. Neuroimaging Clin N Am. 2006; (4): 633-54, ix
- New enzyme for reductive cancer chemotherapy, YieF, and its improvement by directed evolution. Mol Cancer Ther. 2006; (1): 97-103
- Releasable luciferin-transporter conjugates: tools for the real-time analysis of cellular uptake and release. J Am Chem Soc. 2006; (20): 6526-7
- Selective intratumoral amplification of an antiangiogenic vector by an oncolytic virus produces enhanced antivascular and anti-tumor efficacy. Mol Ther. 2006; (5): 938-46
- Systemic effects of orally-administered zinc and tin (IV) metalloporphyrins on heme oxygenase expression in mice. Pediatr Res. 2006; (5): 667-72
- The effectiveness of oral tin mesoporphyrin prophylaxis in reducing bilirubin production after an oral heme load in a transgenic mouse model. Biol Neonate. 2006; (3): 139-46
- Bone morphogenetic protein 2 and retinoic acid accelerate in vivo bone formation, osteoclast recruitment, and bone turnover. Tissue Eng. 2005 Mar-Apr; (3-4): 645-58
- Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo. J Biomed Opt. 2005 Jul-Aug; (4): 41210
- Adoptive transfer of mast cells does not enhance the impaired survival of Kit(W)/Kit(W-v) mice in a model of low dose intraperitoneal infection with bioluminescent Salmonella typhimurium. Immunol Lett. 2005; (1): 122-9
- Bioluminescence regenerative cycle (BRC) system: theoretical considerations for nucleic acid quantification assays. Biophys Chem. 2005; (3): 175-85
- Breast-milk shedding of drug-resistant HIV-1 subtype C in women exposed to single-dose nevirapine. J Infect Dis. 2005; (7): 1260-4
- Ex vivo expanded dendritic cells home to T-cell zones of lymphoid organs and survive in vivo after allogeneic bone marrow transplantation. Am J Pathol. 2005; (5): 1321-31
- Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury. J Immunol. 2005; (1): 547-54
- In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets. Blood. 2005; (3): 1113-22
- In vivo visualization of cardiac allograft rejection and trafficking passenger leukocytes using bioluminescence imaging. Circulation. 2005; (9 Suppl): I105-10
- Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation. Transplantation. 2005; (1): 134-9
- Monitoring age-related susceptibility of young mice to oral Salmonella enterica serovar Typhimurium infection using an in vivo murine model. Pediatr Res. 2005; (1): 153-8
- Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model. Mol Ther. 2005; (3): 562-8
- Confocal fluorescence microscope with dual-axis architecture and biaxial postobjective scanning. J Biomed Opt. 2004 Jul-Aug; (4): 735-42
- A genetic reporter of thermal stress defines physiologic zones over a defined temperature range. FASEB J. 2004; (2): 264-71
- Adipose-derived adult stromal cells heal critical-size mouse calvarial defects. Nat Biotechnol. 2004; (5): 560-7
- Apoptosis in a rodent model of cranial suture fusion: in situ imaging and gene expression analysis. Plast Reconstr Surg. 2004; (7): 2037-47
- Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals. Mol Imaging. 2004; (1): 43-54
- In vivo bioluminescence imaging for integrated studies of infection. Cell Microbiol. 2004; (4): 303-17
- Multi-modality imaging identifies key times for annexin V imaging as an early predictor of therapeutic outcome. Mol Imaging. 2004; (1): 1-8
- The E47 transcription factor negatively regulates CD5 expression during thymocyte development. Proc Natl Acad Sci U S A. 2004; (11): 3898-902
- Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor. J Nucl Med. 2004; (8): 1373-80
- A potent and specific morpholino antisense inhibitor of hepatitis C translation in mice. Hepatology. 2003; (2): 503-8
- Advancing molecular therapies through in vivo bioluminescent imaging. Mol Imaging. 2003; (2): 75-86
- Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection. Opt Lett. 2003; (20): 1915-7
- Dual-axis confocal microscope for high-resolution in vivo imaging. Opt Lett. 2003; (6): 414-6
- Effects of metalloporphyrins on heme oxygenase-1 transcription: correlative cell culture assays guide in vivo imaging. Mol Imaging. 2003; (3): 138-49
- Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging. Blood. 2003; (2): 640-8
- Treatment of autoimmune disease by adoptive cellular gene therapy. Ann N Y Acad Sci. 2003: 512-9
- Adoptive cellular gene therapy of autoimmune disease. Autoimmun Rev. 2002; (4): 213-9
- Advances in in vivo bioluminescence imaging of gene expression. Annu Rev Biomed Eng. 2002: 235-60
- Advancing animal models of neoplasia through in vivo bioluminescence imaging. Eur J Cancer. 2002; (16): 2128-36
- It's not just about anatomy: in vivo bioluminescence imaging as an eyepiece into biology. J Magn Reson Imaging. 2002; (4): 378-87
- Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood. 2002; (13): 4660-7
- Regulation of intestine-specific spatiotemporal expression by the rat lactase promoter. J Biol Chem. 2002; (15): 13099-105
- Retroviral gene therapy of collagen-induced arthritis by local delivery of IL-4. Clin Immunol. 2002; (3): 304-14
- Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1. J Mol Med (Berl). 2002; (10): 655-64
- Understanding immune cell trafficking patterns via in vivo bioluminescence imaging. J Cell Biochem Suppl. 2002: 239-48
- Visualization of effective tumor targeting by CD8+ natural killer T cells redirected with bispecific antibody F(ab')(2)HER2xCD3. Cancer Res. 2002; (20): 5785-91
- Visualization of tumor growth and response to NK-T cell based immunotherapy using bioluminescence. Ann Hematol. 2002: S44-5
- Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit. J Immunol. 2001; (4): 2379-87
- Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis. J Clin Invest. 2001; (10): 1293-301
- Bioluminescence imaging of lymphocyte trafficking in vivo. Exp Hematol. 2001; (12): 1353-60
- Carbon monoxide and bilirubin production in neonates. Semin Perinatol. 2001; (2): 85-93
- In vivo patterns of heme oxygenase-1 transcription. J Perinatol. 2001: S119-24; discussion S125-7
- Rapid in vivo functional analysis of transgenes in mice using whole body imaging of luciferase expression. Transgenic Res. 2001; (5): 423-34
- Revealing the spatiotemporal patterns of bacterial infectious diseases using bioluminescent pathogens and whole body imaging. Contrib Microbiol. 2001: 71-88
- Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia. 2000 Jan-Apr; (1-2): 41-52
- Carbon monoxide detection and biological investigations. Trans Am Clin Climatol Assoc. 2000: 61-75
- HIV type 1 envelope subtype C sequences from recent seroconverters in Zimbabwe. AIDS Res Hum Retroviruses. 2000; (10): 973-9
- HO-1 expression in type II pneumocytes after transpulmonary gene delivery. Am J Physiol Lung Cell Mol Physiol. 2000; (6): L1273-9
- Bioluminescence for biological sensing in living mammals. Adv Exp Med Biol. 1999: 775-84
- Noninvasive assessment of tumor cell proliferation in animal models. Neoplasia. 1999; (4): 303-10
- Primary subtype C HIV-1 infection in Harare, Zimbabwe. J Acquir Immune Defic Syndr Hum Retrovirol. 1999; (2): 147-53
- Visualizing the kinetics of tumor-cell clearance in living animals. Proc Natl Acad Sci U S A. 1999; (21): 12044-9
- Bioluminescent indicators in living mammals. Nat Med. 1998; (2): 245-7
- Mother-to-infant transmission of human immunodeficiency virus type 1 involving five envelope sequence subtypes. J Virol. 1997; (2): 1292-300
- Simian immunodeficiency virus from Old World monkeys The Human Retroviruses. 1991: 245-276
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