Quynh-Thu Le

Publications

• An international collaboration to harmonize the quantitative plasma Epstein-Barr virus DNA assay for future biomarker-guided trials in nasopharyngeal carcinoma. Le QT, Zhang Q, Cao H, Cheng AJ, Pinsky BA, Hong RL, Chang JT, Wang CW, Tsao KC, Lo YD, Lee N, Ang KK, Chan AT, Chan KC. Clin Cancer Res. 2013; 19 (8): 2208-15
• Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy. Sasportas LS, Hosford DN, Sodini MA, Waters DJ, Zambricki EA, Barral JK, Graves EE, Brinton TJ, Yock PG, Le QT, Sirjani D. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013
• Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. Ho AS, Tsao GJ, Chen FW, Shen T, Kaplan MJ, Colevas AD, Fischbein NJ, Quon A, Le QT, Pinto HA, Fee WE, Sunwoo JB, Sirjani D, Hara W, Yao M. Cancer. 2013; 119 (7): 1349-56
• Long-term outcomes of surgery followed by radiation therapy for minor salivary gland carcinomas. Zeidan YH, Shultz DB, Murphy JD, An Y, Chan C, Kaplan MJ, Colevas AD, Kong C, Chang DT, Le QT. Laryngoscope. 2013
• Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse. Kong CS, Cao H, Kwok S, Nguyen CM, Jordan RC, Beaudry VG, Attardi LD, Le QT. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013; 115 (1): 95-103
• Low-Dose Radiation Therapy (2 Gy × 2) in the Treatment of Orbital Lymphoma. Fasola CE, Jones JC, Huang DD, Le QT, Hoppe RT, Donaldson SS. Int J Radiat Oncol Biol Phys. 2013
• Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy. Hong JC, Eclov NC, Yu Y, Rao AK, Dieterich S, Le QT, Diehn M, Sze DY, Loo BW, Kothary N, Maxim PG. J Appl Clin Med Phys. 2013; 14 (2): 4046
• Opportunities and challenges in the era of molecularly targeted agents and radiation therapy. Lin SH, George TJ, Ben-Josef E, Bradley J, Choe KS, Edelman MJ, Guha C, Krishnan S, Lawrence TS, Le QT, Lu B, Mehta M, Peereboom D, Sarkaria J, Seong J, Wang D, Welliver MX, Coleman CN, Vikram B, Yoo S, Chung CH. J Natl Cancer Inst. 2013; 105 (10): 686-93
• Radiotherapy for nonadenoid cystic carcinomas of major salivary glands. Chung MP, Tang C, Chan C, Hara WY, Loo BW, Kaplan MJ, Fischbein N, Le QT, Chang DT. Am J Otolaryngol. 2013
• Stereotactic radiosurgery for retreatment of gross perineural invasion in recurrent cutaneous squamous cell carcinoma of the head and neck. Tang C, Fischbein NJ, Murphy JD, Chu KP, Bavan B, Dieterich S, Hara W, Kaplan MJ, Colevas AD, Le QT. Am J Clin Oncol. 2013; 36 (3): 293-8
• Volumetric-modulated arc radiotherapy for skull-base and non-skull-base head and neck cancer: a treatment planning comparison with fixed Beam IMRT. Chen J, Mok E, Wang L, Chen C, Le QT. Technol Cancer Res Treat. 2013; 12 (1): 11-8
• Esophageal tolerance to high-dose stereotactic ablative radiotherapy. Abelson JA, Murphy JD, Loo BW, Chang DT, Daly ME, Wiegner EA, Hancock S, Chang SD, Le QT, Soltys SG, Gibbs IC. Dis Esophagus. 2012 Sep-Oct; 25 (7): 623-9
• A planned neck dissection is not necessary in all patients with N2-3 head-and-neck cancer after sequential chemoradiotherapy. Soltys SG, Choi CY, Fee WE, Pinto HA, Le QT. Int J Radiat Oncol Biol Phys. 2012; 83 (3): 994-9
• CD44(+) cells have cancer stem cell-like properties in nasopharyngeal carcinoma. Janisiewicz AM, Shin JH, Murillo-Sauca O, Kwok S, Le QT, Kong C, Kaplan MJ, Sunwoo JB. Int Forum Allergy Rhinol. 2012; 2 (6): 465-70
• Evaluation of ProExC as a prognostic marker in oropharyngeal squamous cell carcinomas. Mills AM, Beck AH, Pourmand N, Le QT, Kong CS. Am J Surg Pathol. 2012; 36 (8): 1158-64
• Intensity-modulated radiotherapy for tumors of the nasal cavity and paranasal sinuses: clinical outcomes and patterns of failure. Wiegner EA, Daly ME, Murphy JD, Abelson J, Chapman CH, Chung M, Yu Y, Colevas AD, Kaplan MJ, Fischbein N, Le QT, Chang DT. Int J Radiat Oncol Biol Phys. 2012; 83 (1): 243-51
• Intrafraction verification of gated RapidArc by using beam-level kilovoltage X-ray images. Li R, Mok E, Chang DT, Daly M, Loo BW, Diehn M, Le QT, Koong A, Xing L. Int J Radiat Oncol Biol Phys. 2012; 83 (5): e709-15
• Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy. Abelson JA, Murphy JD, Trakul N, Bazan JG, Maxim PG, Graves EE, Quon A, Le QT, Diehn M, Loo BW. Lung Cancer. 2012; 78 (3): 219-24
• Metabolic tumor volume is an independent prognostic factor in patients treated definitively for non-small-cell lung cancer. Lee P, Bazan JG, Lavori PW, Weerasuriya DK, Quon A, Le QT, Wakelee HA, Graves EE, Loo BW. Clin Lung Cancer. 2012; 13 (1): 52-8
• Prognostic and predictive significance of plasma HGF and IL-8 in a phase III trial of chemoradiation with or without tirapazamine in locoregionally advanced head and neck cancer. Le QT, Fisher R, Oliner KS, Young RJ, Cao H, Kong C, Graves E, Hicks RJ, McArthur GA, Peters L, O'Sullivan B, Giaccia A, Rischin D. Clin Cancer Res. 2012; 18 (6): 1798-807
• Prognostic value of metabolic tumor volume and velocity in predicting head-and-neck cancer outcomes. Chu KP, Murphy JD, La TH, Krakow TE, Iagaru A, Graves EE, Hsu A, Maxim PG, Loo B, Chang DT, Le QT. Int J Radiat Oncol Biol Phys. 2012; 83 (5): 1521-7
• Quantitation of human papillomavirus DNA in plasma of oropharyngeal carcinoma patients. Cao H, Banh A, Kwok S, Shi X, Wu S, Krakow T, Khong B, Bavan B, Bala R, Pinsky BA, Colevas D, Pourmand N, Koong AC, Kong CS, Le QT. Int J Radiat Oncol Biol Phys. 2012; 82 (3): e351-8
• SU-E-T-492: The Dosimetric and Clinical Impact of the Metallic Dental Implants on Radiation Dose Distributions in IMRT Head and Neck Cancer Patients. Wang L, Xing L, Le Q. Med Phys. 2012; 39 (6): 3818
• Salvage Treatment for Locally Recurrent Nasopharyngeal Carcinoma (NPC). Chen C, Fee W, Chen J, Chan C, Khong B, Hara W, Goffinet D, Li D, Le QT. Am J Clin Oncol. 2012
• Stereotactic ablative radiotherapy for reirradiation of locally recurrent lung tumors. Trakul N, Harris JP, Le QT, Hara WY, Maxim PG, Loo BW, Diehn M. J Thorac Oncol. 2012; 7 (9): 1462-5
• Tumor volume-adapted dosing in stereotactic ablative radiotherapy of lung tumors. Trakul N, Chang CN, Harris J, Chapman C, Rao A, Shen J, Quinlan-Davidson S, Filion EJ, Wakelee HA, Colevas AD, Whyte RI, Dieterich S, Maxim PG, Hristov D, Tran P, Le QT, Loo BW, Diehn M. Int J Radiat Oncol Biol Phys. 2012; 84 (1): 231-7
• Validation that metabolic tumor volume predicts outcome in head-and-neck cancer. Tang C, Murphy JD, Khong B, La TH, Kong C, Fischbein NJ, Colevas AD, Iagaru AH, Graves EE, Loo BW, Le QT. Int J Radiat Oncol Biol Phys. 2012; 83 (5): 1514-20
• A novel aldehyde dehydrogenase-3 activator leads to adult salivary stem cell enrichment in vivo. Banh A, Xiao N, Cao H, Chen CH, Kuo P, Krakow T, Bavan B, Khong B, Yao M, Ha C, Kaplan MJ, Sirjani D, Jensen K, Kong CS, Mochly-Rosen D, Koong AC, Le QT. Clin Cancer Res. 2011; 17 (23): 7265-72
• Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity. Murphy JD, Chisholm KM, Daly ME, Wiegner EA, Truong D, Iagaru A, Maxim PG, Loo BW, Graves EE, Kaplan MJ, Kong C, Le QT. Radiother Oncol. 2011; 101 (3): 356-61
• Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with radiation therapy (RTOG 9003). Chung CH, Dignam JJ, Hammond ME, Klimowicz AC, Petrillo SK, Magliocco A, Jordan R, Trotti A, Spencer S, Cooper JS, Le QT, Ang KK. J Clin Oncol. 2011; 29 (10): 1326-34
• Head and neck cancer-specific survival based on socioeconomic status in Asians and Pacific Islanders. Chu KP, Shema S, Wu S, Gomez SL, Chang ET, Le QT. Cancer. 2011; 117 (9): 1935-45
• High retention and safety of percutaneously implanted endovascular embolization coils as fiducial markers for image-guided stereotactic ablative radiotherapy of pulmonary tumors. Hong JC, Yu Y, Rao AK, Dieterich S, Maxim PG, Le QT, Diehn M, Sze DY, Kothary N, Loo BW. Int J Radiat Oncol Biol Phys. 2011; 81 (1): 85-90
• Intensity-modulated and image-guided radiation therapy for head and neck cancers. Chu KP, Le QT. Front Radiat Ther Oncol. 2011: 43 217-54
• Intensity-modulated radiotherapy for locally advanced cancers of the larynx and hypopharynx. Daly ME, Le QT, Jain AK, Maxim PG, Hsu A, Loo BW, Kaplan MJ, Fischbein NJ, Colevas AD, Pinto H, Chang DT. Head Neck. 2011; 33 (1): 103-11
• Intensity-modulated radiotherapy for oral cavity squamous cell carcinoma: patterns of failure and predictors of local control. Daly ME, Le QT, Kozak MM, Maxim PG, Murphy JD, Hsu A, Loo BW, Kaplan MJ, Fischbein NJ, Chang DT. Int J Radiat Oncol Biol Phys. 2011; 80 (5): 1412-22
• MYB expression and translocation in adenoid cystic carcinomas and other salivary gland tumors with clinicopathologic correlation. West RB, Kong C, Clarke N, Gilks T, Lipsick JS, Cao H, Kwok S, Montgomery KD, Varma S, Le QT. Am J Surg Pathol. 2011; 35 (1): 92-9
• On-board imaging validation of optically guided stereotactic radiosurgery positioning system for conventionally fractionated radiotherapy for paranasal sinus and skull base cancer. Maxim PG, Loo BW, Murphy JD, Chu KP, Hsu A, Le QT. Int J Radiat Oncol Biol Phys. 2011; 81 (4): 1153-9
• Palifermin reduces severe mucositis in definitive chemoradiotherapy of locally advanced head and neck cancer: a randomized, placebo-controlled study. Le QT, Kim HE, Schneider CJ, Muraközy G, Skladowski K, Reinisch S, Chen Y, Hickey M, Mo M, Chen MG, Berger D, Lizambri R, Henke M. J Clin Oncol. 2011; 29 (20): 2808-14
• Postradiation metabolic tumor volume predicts outcome in head-and-neck cancer. Murphy JD, La TH, Chu K, Quon A, Fischbein NJ, Maxim PG, Graves EE, Loo BW, Le QT. Int J Radiat Oncol Biol Phys. 2011; 80 (2): 514-21
• Results from a single institution phase II trial of concurrent docetaxel/carboplatin/radiotherapy followed by surgical resection and consolidation docetaxel/carboplatin in stage III non-small-cell lung cancer. Das M, Donington JS, Murphy J, Kozak M, Eclov N, Whyte RI, Hoang CD, Zhou L, Le QT, Loo BW, Wakelee H. Clin Lung Cancer. 2011; 12 (5): 280-5
• Tumor galectin-1 mediates tumor growth and metastasis through regulation of T-cell apoptosis. Banh A, Zhang J, Cao H, Bouley DM, Kwok S, Kong C, Giaccia AJ, Koong AC, Le QT. Cancer Res. 2011; 71 (13): 4423-31
• Tumor volume as a potential imaging-based risk-stratification factor in trimodality therapy for locally advanced non-small cell lung cancer. Kozak MM, Murphy JD, Schipper ML, Donington JS, Zhou L, Whyte RI, Shrager JB, Hoang CD, Bazan J, Maxim PG, Graves EE, Diehn M, Hara WY, Quon A, Le QT, Wakelee HA, Loo BW. J Thorac Oncol. 2011; 6 (5): 920-6
• Cetuximab-based immunotherapy and radioimmunotherapy of head and neck squamous cell carcinoma. Niu G, Sun X, Cao Q, Courter D, Koong A, Le QT, Gambhir SS, Chen X. Clin Cancer Res. 2010; 16 (7): 2095-105
• Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer. Ho AS, Huang X, Cao H, Christman-Skieller C, Bennewith K, Le QT, Koong AC. Transl Oncol. 2010; 3 (2): 109-13
• Dose reconstruction for volumetric modulated arc therapy (VMAT) using cone-beam CT and dynamic log files. Qian J, Lee L, Liu W, Chu K, Mok E, Luxton G, Le QT, Xing L. Phys Med Biol. 2010; 55 (13): 3597-610
• Higher incidence of head and neck cancers among Vietnamese American men in California. Filion EJ, McClure LA, Huang D, Seng K, Kaplan MJ, Colevas AD, Gomez SL, Chang ET, Le QT. Head Neck. 2010; 32 (10): 1336-44
• Hypoxia in models of lung cancer: implications for targeted therapeutics. Graves EE, Vilalta M, Cecic IK, Erler JT, Tran PT, Felsher D, Sayles L, Sweet-Cordero A, Le QT, Giaccia AJ. Clin Cancer Res. 2010; 16 (19): 4843-52
• Image-based modeling of tumor shrinkage in head and neck radiation therapy. Chao M, Xie Y, Moros EG, Le QT, Xing L. Med Phys. 2010; 37 (5): 2351-8
• Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth. Spiotto MT, Banh A, Papandreou I, Cao H, Galvez MG, Gurtner GC, Denko NC, Le QT, Koong AC. Cancer Res. 2010; 70 (1): 78-88
• In response to dr. H. Christiansen et Al. Downing L, Wolden S, Le QT. Int J Radiat Oncol Biol Phys. 2010; 76 (5): 1601
• Intensity-modulated radiotherapy in the treatment of oropharyngeal cancer: clinical outcomes and patterns of failure. Daly ME, Le QT, Maxim PG, Loo BW, Kaplan MJ, Fischbein NJ, Pinto H, Chang DT. Int J Radiat Oncol Biol Phys. 2010; 76 (5): 1339-46
• Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial. Rischin D, Young RJ, Fisher R, Fox SB, Le QT, Peters LJ, Solomon B, Choi J, O'Sullivan B, Kenny LM, McArthur GA. J Clin Oncol. 2010; 28 (27): 4142-8
• The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways. Courter D, Cao H, Kwok S, Kong C, Banh A, Kuo P, Bouley DM, Vice C, Brustugun OT, Denko NC, Koong AC, Giaccia A, Le QT. PLoS One. 2010; 5 (3): e9633
• The tumor microenvironment in non-small-cell lung cancer. Graves EE, Maity A, Le QT. Semin Radiat Oncol. 2010; 20 (3): 156-63
• Comparison of treatment results between adult and juvenile nasopharyngeal carcinoma. Downing NL, Wolden S, Wong P, Petrik DW, Hara W, Le QT. Int J Radiat Oncol Biol Phys. 2009; 75 (4): 1064-70
• Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, Le QT, Giaccia AJ. Cancer Cell. 2009; 15 (1): 35-44
• Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. Huang X, Ding L, Bennewith KL, Tong RT, Welford SM, Ang KK, Story M, Le QT, Giaccia AJ. Mol Cell. 2009; 35 (6): 856-67
• Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis. Chang ST, Zahn JM, Horecka J, Kunz PL, Ford JM, Fisher GA, Le QT, Chang DT, Ji H, Koong AC. J Transl Med. 2009: 7 105
• Integrating biologically targeted therapy in head and neck squamous cell carcinomas. Le QT, Raben D. Semin Radiat Oncol. 2009; 19 (1): 53-62
• Metabolic tumor volume predicts for recurrence and death in head-and-neck cancer. La TH, Filion EJ, Turnbull BB, Chu JN, Lee P, Nguyen K, Maxim P, Quon A, Graves EE, Loo BW, Le QT. Int J Radiat Oncol Biol Phys. 2009; 74 (5): 1335-41
• Mucositis-related morbidity and resource utilization in head and neck cancer patients receiving radiation therapy with or without chemotherapy. Murphy BA, Beaumont JL, Isitt J, Garden AS, Gwede CK, Trotti AM, Meredith RF, Epstein JB, Le QT, Brizel DM, Bellm LA, Wells N, Cella D. J Pain Symptom Manage. 2009; 38 (4): 522-32
• PET of EGFR antibody distribution in head and neck squamous cell carcinoma models. Niu G, Li Z, Xie J, Le QT, Chen X. J Nucl Med. 2009; 50 (7): 1116-23
• The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas. Kong CS, Narasimhan B, Cao H, Kwok S, Erickson JP, Koong A, Pourmand N, Le QT. Int J Radiat Oncol Biol Phys. 2009; 74 (2): 553-61
• Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03. Le QT, Harris J, Magliocco AM, Kong CS, Diaz R, Shin B, Cao H, Trotti A, Erler JT, Chung CH, Dicker A, Pajak TF, Giaccia AJ, Ang KK. J Clin Oncol. 2009; 27 (26): 4281-6
• X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas. Romero-Ramirez L, Cao H, Regalado MP, Kambham N, Siemann D, Kim JJ, Le QT, Koong AC. Transl Oncol. 2009; 2 (1): 31-8
• Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice. Choi CY, Chan DA, Paulmurugan R, Sutphin PD, Le QT, Koong AC, Zundel W, Gambhir SS, Giaccia AJ. Mol Imaging. 2008 May-Jun; 7 (3): 139-46
• Clinical biomarkers for hypoxia targeting. Le QT, Courter D. Cancer Metastasis Rev. 2008; 27 (3): 351-62
• Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma. Hara W, Loo BW, Goffinet DR, Chang SD, Adler JR, Pinto HA, Fee WE, Kaplan MJ, Fischbein NJ, Le QT. Int J Radiat Oncol Biol Phys. 2008; 71 (2): 393-400
• In vivo 1H magnetic resonance spectroscopy of lactate in patients with stage IV head and neck squamous cell carcinoma. Le QT, Koong A, Lieskovsky YY, Narasimhan B, Graves E, Pinto H, Brown JM, Spielman D. Int J Radiat Oncol Biol Phys. 2008; 71 (4): 1151-7
• Linac-based on-board imaging feasibility and the dosimetric consequences of head roll in head-and-neck IMRT plans. Kim GY, Pawlicki T, Le QT, Luxton G. Med Dosim. 2008; 33 (1): 93-9
• Lower osteopontin plasma levels are associated with superior outcomes in advanced non-small-cell lung cancer patients receiving platinum-based chemotherapy: SWOG Study S0003. Mack PC, Redman MW, Chansky K, Williamson SK, Farneth NC, Lara PN, Franklin WA, Le QT, Crowley JJ, Gandara DR. J Clin Oncol. 2008; 26 (29): 4771-6
• Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file. Lee L, Le QT, Xing L. Int J Radiat Oncol Biol Phys. 2008; 70 (2): 634-44
• Clinical role of 18F-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma. Quon A, Fischbein NJ, McDougall IR, Le QT, Loo BW, Pinto H, Kaplan MJ. J Nucl Med. 2007: 48 Suppl 1 58S-67S
• Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma. Daly ME, Lieskovsky Y, Pawlicki T, Yau J, Pinto H, Kaplan M, Fee WE, Koong A, Goffinet DR, Xing L, Le QT. Head Neck. 2007; 29 (3): 211-20
• Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas. Le QT, Kong C, Lavori PW, O'byrne K, Erler JT, Huang X, Chen Y, Cao H, Tibshirani R, Denko N, Giaccia AJ, Koong AC. Int J Radiat Oncol Biol Phys. 2007; 69 (1): 167-75
• Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches. Le QT, Int J Radiat Oncol Biol Phys. 2007; 69 (2 Suppl): S56-8
• Metabolic tumor burden predicts for disease progression and death in lung cancer. Lee P, Weerasuriya DK, Lavori PW, Quon A, Hara W, Maxim PG, Le QT, Wakelee HA, Donington JS, Graves EE, Loo BW. Int J Radiat Oncol Biol Phys. 2007; 69 (2): 328-33
• Nasopharyngeal and oropharyngeal carcinomas: target delineation, therapy delivery and stereotactic boost procedures with intensity-modulated/ image-guided radiation therapy. Le QT, Front Radiat Ther Oncol. 2007: 40 208-31
• Quantification of motion of different thoracic locations using four-dimensional computed tomography: implications for radiotherapy planning. Maxim PG, Loo BW, Shirazi H, Thorndyke B, Luxton G, Le QT. Int J Radiat Oncol Biol Phys. 2007; 69 (5): 1395-401
• A multidisciplinary approach to management in a patient with bilateral superior sulcus non-small-cell lung carcinoma. Roy MS, Le QT, Donington JS, Wakelee HA. Clin Lung Cancer. 2006; 8 (2): 146-8
• Advanced-staged tonsillar squamous carcinoma: organ preservation versus surgical management of the primary site. Shirazi HA, Sivanandan R, Goode R, Fee WE, Kaplan MJ, Pinto HA, Goffinet DR, Le QT. Head Neck. 2006; 28 (7): 587-94
• An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers. Le QT, Chen E, Salim A, Cao H, Kong CS, Whyte R, Donington J, Cannon W, Wakelee H, Tibshirani R, Mitchell JD, Richardson D, O'Byrne KJ, Koong AC, Giaccia AJ. Clin Cancer Res. 2006; 12 (5): 1507-14
• Comment on: osteopontin as toxic marker. Le QT, Cao H, Koong A, Giaccia A. Radiother Oncol. 2006; 78 (2): 230; author reply 230-1
• Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. Dornhöfer N, Spong S, Bennewith K, Salim A, Klaus S, Kambham N, Wong C, Kaper F, Sutphin P, Nacamuli R, Nacalumi R, Höckel M, Le Q, Longaker M, Yang G, Koong A, Giaccia A. Cancer Res. 2006; 66 (11): 5816-27
• Indirect MR lymphangiography of the head and neck using conventional gadolinium contrast: a pilot study in humans. Loo BW, Draney MT, Sivanandan R, Ruehm SG, Pawlicki T, Xing L, Herfkens RJ, Le QT. Int J Radiat Oncol Biol Phys. 2006; 66 (2): 462-8
• Lung cancer in women: exploring sex differences in susceptibility, biology, and therapeutic response. Donington JS, Le QT, Wakelee HA. Clin Lung Cancer. 2006; 8 (1): 22-9
• Lysyl oxidase is essential for hypoxia-induced metastasis. Erler JT, Bennewith KL, Nicolau M, Dornhöfer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ. Nature. 2006; 440 (7088): 1222-6
• Mature results from a randomized Phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck squamous cell carcinomas. Le QT, Taira A, Budenz S, Jo Dorie M, Goffinet DR, Fee WE, Goode R, Bloch D, Koong A, Martin Brown J, Pinto HA. Cancer. 2006; 106 (9): 1940-9
• Plasma osteopontin is an independent prognostic marker for head and neck cancers. Petrik D, Lavori PW, Cao H, Zhu Y, Wong P, Christofferson E, Kaplan MJ, Pinto HA, Sutphin P, Koong AC, Giaccia AJ, Le QT. J Clin Oncol. 2006; 24 (33): 5291-7
• Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors. Le QT, Loo BW, Ho A, Cotrutz C, Koong AC, Wakelee H, Kee ST, Constantinescu D, Whyte RI, Donington J. J Thorac Oncol. 2006; 1 (8): 802-9
• A comparison study of different PCR assays in measuring circulating plasma epstein-barr virus DNA levels in patients with nasopharyngeal carcinoma. Le QT, Jones CD, Yau TK, Shirazi HA, Wong PH, Thomas EN, Patterson BK, Lee AW, Zehnder JL. Clin Cancer Res. 2005; 11 (16): 5700-7
• A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia. Nelson DW, Cao H, Zhu Y, Sunar-Reeder B, Choi CY, Faix JD, Brown JM, Koong AC, Giaccia AJ, Le QT. Cancer Res. 2005; 65 (14): 6151-8
• Galectin-1: a link between tumor hypoxia and tumor immune privilege. Le QT, Shi G, Cao H, Nelson DW, Wang Y, Chen EY, Zhao S, Kong C, Richardson D, O'Byrne KJ, Giaccia AJ, Koong AC. J Clin Oncol. 2005; 23 (35): 8932-41
• Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer. Zhu Y, Denhardt DT, Cao H, Sutphin PD, Koong AC, Giaccia AJ, Le QT. Oncogene. 2005; 24 (43): 6555-63
• Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. Chen Y, Feldman DE, Deng C, Brown JA, De Giacomo AF, Gaw AF, Shi G, Le QT, Brown JM, Koong AC. Mol Cancer Res. 2005; 3 (12): 669-77
• Nonsurgical therapy for stages I and II non-small cell lung cancer. Le QT, Petrik DW. Hematol Oncol Clin North Am. 2005; 19 (2): 237-61, v-vi
• Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer. Koong AC, Christofferson E, Le QT, Goodman KA, Ho A, Kuo T, Ford JM, Fisher GA, Greco R, Norton J, Yang GP. Int J Radiat Oncol Biol Phys. 2005; 63 (2): 320-3
• Positron-emission tomography for surveillance of head and neck cancer. Ryan WR, Fee WE, Le QT, Pinto HA. Laryngoscope. 2005; 115 (4): 645-50
• Hypoxic gene expression and metastasis. Le QT, Denko NC, Giaccia AJ. Cancer Metastasis Rev. 2004 Aug-Dec; 23 (3-4): 293-310
• Extranodal nonorbital indolent lymphomas of the head and neck: relationship between tumor control and radiotherapy. MacDermed D, Thurber L, George TI, Hoppe RT, Le QT. Int J Radiat Oncol Biol Phys. 2004; 59 (3): 788-95
• Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling. Chen Y, Shi G, Xia W, Kong C, Zhao S, Gaw AF, Chen EY, Yang GP, Giaccia AJ, Le QT, Koong AC. Cancer Res. 2004; 64 (20): 7302-10
• Lens dose in MLC-based IMRT treatments of the head and neck. Pawlicki T, Luxton G, Le QT, Findley D, Ma CM. Int J Radiat Oncol Biol Phys. 2004; 59 (1): 293-9
• Long-term results of 100 consecutive comprehensive neck dissections: implications for selective neck dissections. Sivanandan R, Kaplan MJ, Lee KJ, Lebl D, Pinto H, Le QT, Goffinet DR, Fee WE. Arch Otolaryngol Head Neck Surg. 2004; 130 (12): 1369-73
• Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer. Koong AC, Le QT, Ho A, Fong B, Fisher G, Cho C, Ford J, Poen J, Gibbs IC, Mehta VK, Kee S, Trueblood W, Yang G, Bastidas JA. Int J Radiat Oncol Biol Phys. 2004; 58 (4): 1017-21
• Phase I study of tirapazamine plus cisplatin/etoposide and concurrent thoracic radiotherapy in limited-stage small cell lung cancer (S0004): a Southwest Oncology Group study. Le QT, McCoy J, Williamson S, Ryu J, Gaspar LE, Edelman MJ, Dakhil SR, Sides SD, Crowley JJ, Gandara DR. Clin Cancer Res. 2004; 10 (16): 5418-24
• Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms. Su CK, Mehta V, Ravikumar L, Shah R, Pinto H, Halpern J, Koong A, Goffinet D, Le QT. Int J Radiat Oncol Biol Phys. 2004; 60 (1): 171-7
• Sample classification from protein mass spectrometry, by 'peak probability contrasts'. Tibshirani R, Hastie T, Narasimhan B, Soltys S, Shi G, Koong A, Le QT. Bioinformatics. 2004; 20 (17): 3034-44
• The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers. Soltys SG, Le QT, Shi G, Tibshirani R, Giaccia AJ, Koong AC. Clin Cancer Res. 2004; 10 (14): 4806-12
• XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, Le QT, Koong AC. Cancer Res. 2004; 64 (17): 5943-7
• Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients. Le QT, Kovacs MS, Dorie MJ, Koong A, Terris DJ, Pinto HA, Goffinet DR, Nowels K, Bloch D, Brown JM. Int J Radiat Oncol Biol Phys. 2003; 56 (2): 375-83
• HIF-alpha, a gender independent transcription factor. Le QT, Giaccia AJ. Clin Cancer Res. 2003; 9 (7): 2391-3
• Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. Le QT, Sutphin PD, Raychaudhuri S, Yu SC, Terris DJ, Lin HS, Lum B, Pinto HA, Koong AC, Giaccia AJ. Clin Cancer Res. 2003; 9 (1): 59-67
• Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma. Le QT, Tate D, Koong A, Gibbs IC, Chang SD, Adler JR, Pinto HA, Terris DJ, Fee WE, Goffinet DR. Int J Radiat Oncol Biol Phys. 2003; 56 (4): 1046-54
• Long-term outcomes after external beam irradiation and brachytherapy boost for base-of-tongue cancers. Gibbs IC, Le QT, Shah RD, Terris DJ, Fee WE, Goffinet DR. Int J Radiat Oncol Biol Phys. 2003; 57 (2): 489-94
• Patterns of patient movement during frameless image-guided radiosurgery. Murphy MJ, Chang SD, Gibbs IC, Le QT, Hai J, Kim D, Martin DP, Adler JR. Int J Radiat Oncol Biol Phys. 2003; 55 (5): 1400-8
• Radiation therapy for intracranial germ cell tumors. Haas-Kogan DA, Missett BT, Wara WM, Donaldson SS, Lamborn KR, Prados MD, Fisher PG, Huhn SL, Fisch BM, Berger MS, Le QT. Int J Radiat Oncol Biol Phys. 2003; 56 (2): 511-8
• Stereotactic radiosurgery for lung tumors: preliminary report of a phase I trial. Whyte RI, Crownover R, Murphy MJ, Martin DP, Rice TW, DeCamp MM, Rodebaugh R, Weinhous MS, Le QT. Ann Thorac Surg. 2003; 75 (4): 1097-101
• Therapeutic exploitation of the physiological and molecular genetic alterations in head and neck cancer. Le QT, Giaccia AJ. Clin Cancer Res. 2003; 9 (12): 4287-95
• Estimating DNA repair by sequential evaluation of head and neck tumor radiation sensitivity using the comet assay. Terris DJ, Ho EY, Ibrahim HZ, Dorie MJ, Kovacs MS, Le QT, Koong AC, Pinto HA, Brown JM. Arch Otolaryngol Head Neck Surg. 2002; 128 (6): 698-702
• Primary radiotherapy for localized orbital MALT lymphoma. Le QT, Eulau SM, George TI, Hildebrand R, Warnke RA, Donaldson SS, Hoppe RT. Int J Radiat Oncol Biol Phys. 2002; 52 (3): 657-63
• The effectiveness of breath-holding to stabilize lung and pancreas tumors during radiosurgery. Murphy MJ, Martin D, Whyte R, Hai J, Ozhasoglu C, Le QT. Int J Radiat Oncol Biol Phys. 2002; 53 (2): 475-82
• Tirapazamine: prototype for a novel class of therapeutic agents targeting tumor hypoxia. Gandara DR, Lara PN, Goldberg Z, Le QT, Mack PC, Lau DH, Gumerlock PH. Semin Oncol. 2002; 29 (1 Suppl 4): 102-9
• Tumor hypoxia is important in radiotherapy, but how should we measure it? Brown JM, Le QT. Int J Radiat Oncol Biol Phys. 2002; 54 (5): 1299-301
• Daily low-dose carboplatin as a radiation sensitizer for newly diagnosed malignant glioma. Peterson K, Harsh G, Fisher PG, Adler J, Le Q. J Neurooncol. 2001; 53 (1): 27-32
• Image-guided hypo-fractionated stereotactic radiosurgery to spinal lesions. Ryu SI, Chang SD, Kim DH, Murphy MJ, Le QT, Martin DP, Adler JR. Neurosurgery. 2001; 49 (4): 838-46
• Image-guided radiosurgery in the treatment of spinal metastases. Murphy MJ, Chang S, Gibbs I, Le QT, Martin D, Kim D. Neurosurg Focus. 2001; 11 (6): e6
• Role of beam orientation optimization in intensity-modulated radiation therapy. Pugachev A, Li JG, Boyer AL, Hancock SL, Le QT, Donaldson SS, Xing L. Int J Radiat Oncol Biol Phys. 2001; 50 (2): 551-60
• Treatment results and prognostic factors of advanced T3--4 laryngeal carcinoma: the University of California, San Francisco (UCSF) and Stanford University Hospital (SUH) experience. Nguyen-Tan PF, Le QT, Quivey JM, Singer M, Terris DJ, Goffinet DR, Fu KK. Int J Radiat Oncol Biol Phys. 2001; 50 (5): 1172-80
• Candidate genes for the hypoxic tumor phenotype. Koong AC, Denko NC, Hudson KM, Schindler C, Swiersz L, Koch C, Evans S, Ibrahim H, Le QT, Terris DJ, Giaccia AJ. Cancer Res. 2000; 60 (4): 883-7
• Dosimetric effects of patient displacement and collimator and gantry angle misalignment on intensity modulated radiation therapy. Xing L, Lin Z, Donaldson SS, Le QT, Tate D, Goffinet DR, Wolden S, Ma L, Boyer AL. Radiother Oncol. 2000; 56 (1): 97-108
• Head and neck cancer in cardiothoracic transplant recipients. Pollard JD, Hanasono MM, Mikulec AA, Le QT, Terris DJ. Laryngoscope. 2000; 110 (8): 1257-61
• Image-guided radiosurgery for the spine and pancreas. Murphy MJ, Adler JR, Bodduluri M, Dooley J, Forster K, Hai J, Le Q, Luxton G, Martin D, Poen J. Comput Aided Surg. 2000; 5 (4): 278-88
• Lymph node metastasis in maxillary sinus carcinoma. Le QT, Fu KK, Kaplan MJ, Terris DJ, Fee WE, Goffinet DR. Int J Radiat Oncol Biol Phys. 2000; 46 (3): 541-9
• Pancreatic tumors show high levels of hypoxia. Koong AC, Mehta VK, Le QT, Fisher GA, Terris DJ, Brown JM, Bastidas AJ, Vierra M. Int J Radiat Oncol Biol Phys. 2000; 48 (4): 919-22
• Treatment results of carcinoma in situ of the glottis: an analysis of 82 cases. Le QT, Takamiya R, Shu HK, Smitt M, Singer M, Terris DJ, Fee WE, Goffinet DR, Fu KK. Arch Otolaryngol Head Neck Surg. 2000; 126 (11): 1305-12
• Apoptosis-associated proteins and the development of oral squamous cell carcinoma. Schoelch ML, Le QT, Silverman S, McMillan A, Dekker NP, Fu KK, Ziober BL, Regezi JA. Oral Oncol. 1999; 35 (1): 77-85
• Cell cycle proteins and the development of oral squamous cell carcinoma. Schoelch ML, Regezi JA, Dekker NP, Ng IO, McMillan A, Ziober BL, Le QT, Silverman S, Fu KK. Oral Oncol. 1999; 35 (3): 333-42
• DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine. Dorie MJ, Kovacs MS, Gabalski EC, Adam M, Le QT, Bloch DA, Pinto HA, Terris DJ, Brown JM. Neoplasia. 1999; 1 (5): 461-7
• Estimation theory and model parameter selection for therapeutic treatment plan optimization. Xing L, Li JG, Pugachev A, Le QT, Boyer AL. Med Phys. 1999; 26 (11): 2348-58
• Optimization of importance factors in inverse planning. Xing L, Li JG, Donaldson S, Le QT, Boyer AL. Phys Med Biol. 1999; 44 (10): 2525-36
• Post-operative irradiation of minor salivary gland malignancies of the head and neck. Le QT, Birdwell S, Terris DJ, Gabalski EC, Varghese A, Fee WE, Goffinet DR.. Radiotherapy Oncology. 1999; 2 (52): 165-71
• Postoperative irradiation of minor salivary gland malignancies of the head and neck. Le QT, Birdwell S, Terris DJ, Gabalski EC, Varghese A, Fee We, Goffinet DR. Radiother Oncol. 1999; 52 (2): 165-71
• Treatment of maxillary sinus carcinoma: a comparison of the 1997 and 1977 American Joint Committee on cancer staging systems. Le QT, Fu KK, Kaplan M, Terris DJ, Fee WE, Goffinet DR. Cancer. 1999; 86 (9): 1700-11
• A medical knowledge based system for the section of beam orientations in intensity modulated radiation therapy (IMRT). Le QT, Xing L, Pugachev A, Li J , Donaldson S, Goffinet DR, Hancock S, Boyer A.. Int J Radiat Oncol Biol Phys. 1998; 3S (45): 246
• Soft-tissue sarcomas. In: Phillips TL, Leibel S, eds. Le QT, Phillips TL, Leibel S.. Textbook of Radiation Oncology, 1st Edition. Philadelphia: WB Saunders. 1998: 1047-1066.
• Spinal cord dose discrepancy in IMRT treated patients at Stanford revealed by Monte Carlo dose verification: clinical summary. Le QT, Guerrero TM, Pawlicki T, Ma CM, Forster KM, Xing L, Luxton G, Boyer AL, Goffinet DR. ,. Int J Radiat Oncol Biol Phys. 1998; 3S (45): 411
• Adult medulloblastoma: an analysis of survival and prognostic factors. Le QT, Weil MD, Wara WM, Lamborn KR, Prados MD, Edwards MS, Gutin PH. Cancer J Sci Am. 1997 Jul-Aug; 3 (4): 238-45
• Influence of fraction size, total dose, and overall time on local control of T1-T2 glottic carcinoma. Le QT, Fu KK, Kroll S, Ryu JK, Quivey JM, Meyler TS, Krieg RM, Phillips TL. Int J Radiat Oncol Biol Phys. 1997; 39 (1): 115-26
• Prognostic factors in adult soft-tissue sarcomas of the head and neck. Le QT, Fu KK, Kroll S, Fitts L, Massullo V, Ferrell L, Kaplan MJ, Phillips TL. Int J Radiat Oncol Biol Phys. 1997; 37 (5): 975-84
• Pattern of recurrence of medulloblastoma after low-dose craniospinal radiotherapy. Wara WM, Le QT, Sneed PK, Larson DA, Prados MD, Levin VA, Edwards MS, Weil MD. Int J Radiat Oncol Biol Phys. 1994; 30 (3): 551-6