Daniel Thomas

Publications

• Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival Daniel Thomas, Daniel Thomas equal contributor, Jason A. Powell equal contributor, Benjamin D. Green, Emma F. Barry, Yuefang Ma, Joanna Woodcock, Stephen Fitter, Andrew C. W. Zannettino, Stuart M. Pitson, Timothy P. Hughes, Angel F. Lopez, Peter R. Shepherd, Andrew H. Wei, Paul G. Ekert, Mark A. Guthridge. PLOS Biology. 2013; 11 (3): e1001515
• Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. Powell JA, Thomas D, Barry EF, Kok CH, McClure BJ, Tsykin A, To LB, Brown A, Lewis ID, Herbert K, Goodall GJ, Speed TP, Asou N, Jacob B, Osato M, Haylock DN, Nilsson SK, D'Andrea RJ, Lopez AF, Guthridge MA. Blood. 2009; 114 (23): 4859-70
• Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells. Jin L, Lee EM, Ramshaw HS, Busfield SJ, Peoppl AG, Wilkinson L, Guthridge MA, Thomas D, Barry EF, Boyd A, Gearing DP, Vairo G, Lopez AF, Dick JE, Lock RB. Cell Stem Cell. 2009; 5 (1): 31-42
• The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease. Hercus TR, Thomas D, Guthridge MA, Ekert PG, King-Scott J, Parker MW, Lopez AF. Blood. 2009; 114 (7): 1289-98
• Phosphorylation of Serine 779 in Fibroblast Growth Factor Receptor 1 and 2 by Protein Kinase C epsilon regulates Ras/MAP kinase signaling and neuronal differentiation. Lonic A, Powell JA, Kong Y, Thomas D, Holien JK, Truong N, Parker MW, Guthridge MA. J Biol Chem. 2013
• Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers. Roberts KG, Smith AM, McDougall F, Carpenter H, Horan M, Neviani P, Powell JA, Thomas D, Guthridge MA, Perrotti D, Sim AT, Ashman LK, Verrills NM. Cancer Res. 2010; 70 (13): 5438-47
• Molecular basis of cytokine receptor activation. Lopez AF, Hercus TR, Ekert P, Littler DR, Guthridge M, Thomas D, Ramshaw HS, Stomski F, Perugini M, D'Andrea R, Grimbaldeston M, Parker MW. IUBMB Life. 2010; 62 (7): 509-18
• Haematopoietic Growth Factors Daniel Thomas, Angel Lopez. In: Encyclopedia of Life Sciences (ELS) John Wiley and Sons, Ltd: Chichester.. 2009: March
• Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch. Guthridge MA, Powell JA, Barry EF, Stomski FC, McClure BJ, Ramshaw H, Felquer FA, Dottore M, Thomas DT, To B, Begley CG, Lopez AF. EMBO J. 2006; 25 (3): 479-89
• 14-3-3 protein signaling in development and growth factor responses. Thomas D, Guthridge M, Woodcock J, Lopez A. Curr Top Dev Biol. 2005: 67 285-303
• Chromatin remodelling in the biology and treatment of acute leukaemia Daniel Thomas, Bik To. Cancer Reviews: Asia-Pacific. 2004; 2 (2): 109-119
• Regulation of Haematopoiesis by Growth Factors - Emerging Insights and Therapies Daniel Thomas, Angel Lopez. Expert Opinion in Biological Therapy. 2004; 4 (6): 869-79
• Granulocyte Macrophage Colony Stimulating Factor Daniel Thomas, Angel Lopez. Encyclopedia of Hormones; Academic Press. 2003: April 25
• Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF. Stomski FC, Dottore M, Winnall W, Guthridge MA, Woodcock J, Bagley CJ, Thomas DT, Andrews RK, Berndt MC, Lopez AF. Blood. 1999; 94 (6): 1933-42
• Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors. Guthridge MA, Stomski FC, Thomas D, Woodcock JM, Bagley CJ, Berndt MC, Lopez AF. Stem Cells. 1998; 16 (5): 301-13