Jean Y. Tang MD PhD

Publications

• Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women: the Women's Health Initiative. Gamba CA, Swetter SM, Stefanick ML, Kubo J, Desai M, Spaunhurst KM, Sinha AA, Asgari MM, Sturgeon S, Tang JY. Cancer. 2013; 119 (8): 1562-9
• GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas. Atwood SX, Li M, Lee A, Tang JY, Oro AE. Nature. 2013; 494 (7438): 484-8
• Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists. Kim J, Aftab BT, Tang JY, Kim D, Lee AH, Rezaee M, Kim J, Chen B, King EM, Borodovsky A, Riggins GJ, Epstein EH, Beachy PA, Rudin CM. Cancer Cell. 2013; 23 (1): 23-34
• Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome. Tang JY, Mackay-Wiggan JM, Aszterbaum M, Yauch RL, Lindgren J, Chang K, Coppola C, Chanana AM, Marji J, Bickers DR, Epstein EH. N Engl J Med. 2012; 366 (23): 2180-8
• Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial. Tang JY, Fu T, Leblanc E, Manson JE, Feldman D, Linos E, Vitolins MZ, Zeitouni NC, Larson J, Stefanick ML. J Clin Oncol. 2011; 29 (22): 3078-84
• Comment on Basal Cell Carcinoma Rebound After Cessation of Vismodegib in an Individual With Basal Cell Nevus Syndrome. Ally MS, Wysong A, Tang JY, Aasi S. Dermatol Surg. 2013
• Cutaneous human papillomavirus infection and Basal cell carcinoma of the skin. Ally MS, Tang JY, Arron ST. J Invest Dermatol. 2013; 133 (6): 1456-8
• Factors affecting sunscreen use and sun avoidance in a U.S. national sample of organ transplant recipients. Mihalis EL, Wysong A, Boscardin WJ, Tang JY, Chren MM, Arron ST. Br J Dermatol. 2013; 168 (2): 346-53
• New onset of keratoacanthomas after vismodegib treatment for locally advanced basal cell carcinomas: a report of 2 cases. Aasi S, Silkiss R, Tang JY, Wysong A, Liu A, Epstein E, Oro AE, Chang AL. JAMA Dermatol. 2013; 149 (2): 242-3
• Nonmelanoma skin cancer visits and procedure patterns in a nationally representative sample: national ambulatory medical care survey 1995-2007. Wysong A, Linos E, Hernandez-Boussard T, Arron ST, Gladstone H, Tang JY. Dermatol Surg. 2013; 39 (4): 596-602
• The use of aprepitant in brachioradial pruritus. Ally MS, Gamba CS, Peng DH, Tang JY. JAMA Dermatol. 2013; 149 (5): 627-8
• Update on metastatic Basal cell carcinoma: a summary of published cases from 1981 through 2011. Wysong A, Aasi SZ, Tang JY. JAMA Dermatol. 2013; 149 (5): 615-6
• Does a history of eczema predict a future basal cell carcinoma? Gamba CA, Tang JY. J Invest Dermatol. 2012; 132 (11): 2497-9
• Is tanning bed exposure associated with aggressive basal cell carcinoma? Gamba CA, Wysong A, Million L, Aasi S, Kim J, Tang JY. J Clin Oncol. 2012; 30 (32): e333-6
• Nanoelectroablation therapy for murine basal cell carcinoma. Nuccitelli R, Tran K, Athos B, Kreis M, Nuccitelli P, Chang KS, Epstein EH, Tang JY. Biochem Biophys Res Commun. 2012; 424 (3): 446-50
• Pachyonychia congenita patients with mutations in KRT6A have more extensive disease compared with patients who have mutations in KRT16. Spaunhurst KM, Hogendorf AM, Smith FJ, Lingala B, Schwartz ME, Cywinska-Bernas A, Zeman KJ, Tang JY. Br J Dermatol. 2012; 166 (4): 875-8
• Reliability and prevalence of digital image skin types in the United States: results from National Health and Nutrition Examination Survey 2003-2004. Keiser E, Linos E, Kanzler M, Lee W, Sainani KL, Tang JY. J Am Acad Dermatol. 2012; 66 (1): 163-5
• Sun protective behaviors and vitamin D levels in the US population: NHANES 2003-2006. Linos E, Keiser E, Kanzler M, Sainani KL, Lee W, Vittinghoff E, Chren MM, Tang JY. Cancer Causes Control. 2012; 23 (1): 133-40
• Sunscreen use in NCAA collegiate athletes: identifying targets for intervention and barriers to use. Wysong A, Gladstone H, Kim D, Lingala B, Copeland J, Tang JY. Prev Med. 2012; 55 (5): 493-6
• The evolving conception and management challenges of malignant fibrous histiocytoma. Hollmig ST, Kirkland EB, Henderson MT, Tang JY, Gladstone HB. Dermatol Surg. 2012; 38 (12): 1922-9
• Vitamin D in cutaneous carcinogenesis: part I. Tang JY, Fu T, Lau C, Oh DH, Bikle DD, Asgari MM. J Am Acad Dermatol. 2012; 67 (5): 803.e1-12, quiz 815-6
• Vitamin D in cutaneous carcinogenesis: part II. Tang JY, Fu T, Lau C, Oh DH, Bikle DD, Asgari MM. J Am Acad Dermatol. 2012; 67 (5): 817.e1-11; quiz 827-8
• Correlates of low bone mass in children with generalized forms of epidermolysis bullosa. Bruckner AL, Bedocs LA, Keiser E, Tang JY, Doernbrack C, Arbuckle HA, Berman S, Kent K, Bachrach LK. J Am Acad Dermatol. 2011; 65 (5): 1001-9
• Elucidating the role of molecular signaling pathways in the tumorigenesis of basal cell carcinoma. Tang JY, Semin Cutan Med Surg. 2011; 30 (4 Suppl): S6-9
• Emerging treatments and signaling pathway inhibitors. Tang JY, Marghoob AA. Semin Cutan Med Surg. 2011; 30 (4 Suppl): S14-8
• Genotype-phenotype correlations among pachyonychia congenita patients with K16 mutations. Fu T, Leachman SA, Wilson NJ, Smith FJ, Schwartz ME, Tang JY. J Invest Dermatol. 2011; 131 (5): 1025-8
• Hat, shade, long sleeves, or sunscreen? Rethinking US sun protection messages based on their relative effectiveness. Linos E, Keiser E, Fu T, Colditz G, Chen S, Tang JY. Cancer Causes Control. 2011; 22 (7): 1067-71
• Menopausal hormone therapy and risks of melanoma and nonmelanoma skin cancers: women's health initiative randomized trials. Tang JY, Spaunhurst KM, Chlebowski RT, Wactawski-Wende J, Keiser E, Thomas F, Anderson ML, Zeitouni NC, Larson JC, Stefanick ML. J Natl Cancer Inst. 2011; 103 (19): 1469-75
• Subcutaneous nodules in an elderly patient. Necrobiotic xanthogranuloma. Fu T, Zwerner J, Kim J, Tang J. Arch Dermatol. 2011; 147 (10): 1215-20
• Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened. Tang T, Tang JY, Li D, Reich M, Callahan CA, Fu L, Yauch RL, Wang F, Kotkow K, Chang KS, Shpall E, Wu A, Rubin LL, Marsters JC, Epstein EH, Caro I, de Sauvage FJ. Clin Cancer Res. 2011; 17 (10): 3378-87
• Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas. Tang JY, Xiao TZ, Oda Y, Chang KS, Shpall E, Wu A, So PL, Hebert J, Bikle D, Epstein EH. Cancer Prev Res (Phila). 2011; 4 (5): 744-51
• Association of facial skin aging and vitamin D levels in middle-aged white women. Chang AL, Fu T, Amir O, Tang JY. Cancer Causes Control. 2010; 21 (12): 2315-6
• Association of prediagnostic serum vitamin D levels with the development of basal cell carcinoma. Asgari MM, Tang J, Warton ME, Chren MM, Quesenberry CP, Bikle D, Horst RL, Orentreich N, Vogelman JH, Friedman GD. J Invest Dermatol. 2010; 130 (5): 1438-43
• Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice. Tang JY, Aszterbaum M, Athar M, Barsanti F, Cappola C, Estevez N, Hebert J, Hwang J, Khaimskiy Y, Kim A, Lu Y, So PL, Tang X, Kohn MA, McCulloch CE, Kopelovich L, Bickers DR, Epstein EH. Cancer Prev Res (Phila). 2010; 3 (1): 25-34
• High prevalence of vitamin D deficiency in patients with basal cell nevus syndrome. Tang JY, Wu A, Linos E, Parimi N, Lee W, Aszterbaum M, Asgari MM, Bickers DR, Epstein EH. Arch Dermatol. 2010; 146 (10): 1105-10
• Inverse association between serum 25(OH) vitamin D levels and non-melanoma skin cancer in elderly men. Tang JY, Parimi N, Wu A, Boscardin WJ, Shikany JM, Chren MM, Cummings SR, Epstein EH, Bauer DC. Cancer Causes Control. 2010; 21 (3): 387-91
• Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Kim J, Tang JY, Gong R, Kim J, Lee JJ, Clemons KV, Chong CR, Chang KS, Fereshteh M, Gardner D, Reya T, Liu JO, Epstein EH, Stevens DA, Beachy PA. Cancer Cell. 2010; 17 (4): 388-99
• Medical Management of Advanced or Metastatic Basal Cell Carcinomas Jean Y Tang, Ervin H. Epstein. AccessMedicine from McGraw-Hill. 2010
• Novel investigational drugs for basal cell carcinoma. So PL, Tang JY, Epstein EH. Expert Opin Investig Drugs. 2010; 19 (9): 1099-112
• Statin use and risk of basal cell carcinoma. Asgari MM, Tang J, Epstein EH, Chren MM, Warton EM, Quesenberry CP, Go AS, Friedman GD. J Am Acad Dermatol. 2009; 61 (1): 66-72
• Novel Hedgehog pathway targets against basal cell carcinoma. Tang JY, So PL, Epstein EH. Toxicol Appl Pharmacol. 2007; 224 (3): 257-64
• Xeroderma pigmentosum group C in an isolated region of Guatemala. Cleaver JE, Feeney L, Tang JY, Tuttle P. J Invest Dermatol. 2007; 127 (2): 493-6
• Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger KE, Hong WJ, Tusher VG, Tang J, Tibshirani R, Chu G. Proc Natl Acad Sci U S A. 2004; 101 (17): 6635-40
• Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase. Cong F, Tang J, Hwang BJ, Vuong BQ, Chu G, Goff SP. J Biol Chem. 2002; 277 (38): 34870-8
• Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein. Tang J, Chu G. DNA Repair (Amst). 2002; 1 (8): 601-16
• Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis. Tang JY, Hwang BJ, Ford JM, Hanawalt PC, Chu G. Mol Cell. 2000; 5 (4): 737-44
• Inhibition of lecithin-cholesterol acyltransferase and modification of HDL apolipoproteins by aldehydes. McCall MR, Tang JY, Bielicki JK, Forte TM. Arterioscler Thromb Vasc Biol. 1995; 15 (10): 1599-606