Mickey Hu
Publications
- FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage. Nat Commun. 2012: 1000
- ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair. EMBO Rep. 2011; (7): 713-9
- Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks. Cell Cycle. 2011; (24): 4300-10
- Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol Cell. 2011; (5): 529-42
- Inhibition of FOXO3 tumor suppressor function by betaTrCP1 through ubiquitin-mediated degradation in a tumor mouse model. PLoS One. 2010; (7): e11171
- A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation. Oncogene. 2008; (39): 5195-203
- Cadherin-11 promotes the metastasis of prostate cancer cells to bone. Mol Cancer Res. 2008; (8): 1259-67
- Expression of the extracellular domain of OB-cadherin as an Fc fusion protein using bicistronic retroviral expression vector. Protein Expr Purif. 2008; (2): 220-6
- Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis. Breast Cancer Res. 2008; (1): R21
- Functional interaction between FOXO3a and ATM regulates DNA damage response. Nat Cell Biol. 2008; (4): 460-7
- Bone microenvironment and androgen status modulate subcellular localization of ErbB3 in prostate cancer cells. Mol Cancer Res. 2007; (7): 675-84
- Conditional knockout mice reveal an essential role of protein phosphatase 4 in thymocyte development and pre-T-cell receptor signaling. Mol Cell Biol. 2007; (1): 79-91
- Ionizing radiation activates expression of FOXO3a, Fas ligand, and Bim, and induces cell apoptosis. Int J Oncol. 2006; (3): 643-8
- Role of the Akt/FoxO3a pathway in TGF-beta1-mediated mesangial cell dysfunction: a novel mechanism related to diabetic kidney disease. J Am Soc Nephrol. 2006; (12): 3325-35
- Role of IkappaB kinase in tumorigenesis. Future Oncol. 2005; (1): 67-78
- IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell. 2004; (2): 225-37
- Assessment of epidermal growth factor receptor with 99mTc-ethylenedicysteine-C225 monoclonal antibody. Anticancer Drugs. 2003; (1): 49-56
- Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice. Proc Natl Acad Sci U S A. 2003; (11): 6464-8
- Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase. J Biol Chem. 2002; (8): 6391-8
- Genomic structure of the mouse PP4 gene: a developmentally regulated protein phosphatase. Gene. 2001; (1-2): 89-99
- Identification of a candidate human neurohematopoietic stem-cell population. Blood. 2001; (8): 2412-22
- Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling. J Biol Chem. 2001; (22): 18908-14
- A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Blood. 2000; (6): 1957-66
- HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway. J Biol Chem. 2000; (11): 8027-31
- HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway. Cancer Res. 2000; (24): 6841-5
- High tumoral maspin expression is associated with improved survival of patients with oral squamous cell carcinoma. Oncogene. 2000; (20): 2398-403
- E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities. J Biol Chem. 1999; (31): 21495-8
- Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase. Oncogene. 1999; (40): 5514-24
- Human fibroblast growth factor-18 stimulates fibroblast cell proliferation and is mapped to chromosome 14p11. Oncogene. 1999; (16): 2635-42
- Long-term ex vivo maintenance and expansion of transplantable human hematopoietic stem cells. Blood. 1999; (5): 1623-36
- Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines. J Biol Chem. 1999; (11): 7095-102
- FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation. Mol Cell Biol. 1998; (10): 6063-74
- IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes. Gene. 1998; (1): 31-40
- Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activity. J Biol Chem. 1998; (50): 33561-5
- The cytoplasmic domain of stem cell antigen CD34 is essential for cytoadhesion signaling but not sufficient for proliferation signaling. Blood. 1998; (4): 1152-62
- Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction. J Biol Chem. 1997; (36): 22771-5
- JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases. Oncogene. 1997; (19): 2277-87
- Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade. Genes Dev. 1996; (18): 2251-64
- Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14. J Immunol. 1996; (11): 4384-90
- Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell. 1994; (7): 1117-24
- Mapping transcription start points with T4 DNA polymerase. Methods Enzymol. 1993: 446-58
- The Peyer's patch homing receptor. Curr Top Microbiol Immunol. 1993: 125-38
- Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing. Proc Natl Acad Sci U S A. 1992; (17): 8254-8
- Lymphocyte homing receptors. Cold Spring Harb Symp Quant Biol. 1992: 291-308
- Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule. J Cell Biol. 1991; (4): 1149-58
- Targeting the Escherichia coli lac repressor to the mammalian cell nucleus. Gene. 1991; (2): 141-50
- A combination of derepression of the lac operator-repressor system with positive induction by glucocorticoid and metal ions provides a high-level-inducible gene expression system based on the human metallothionein-IIA promoter. Mol Cell Biol. 1990; (12): 6141-51
- The inducible lac operator-repressor system is functional for control of expression of injected DNA in Xenopus oocytes. Gene. 1988; (2): 301-13
- The inducible lac operator-repressor system is functional in mammalian cells. Cell. 1987; (4): 555-66
- Mapping transcription start points on cloned genomic DNA with T4 DNA polymerase: a precise and convenient technique. Gene. 1986; (1): 21-9
- The complete sequence of the mouse skeletal alpha-actin gene reveals several conserved and inverted repeat sequences outside of the protein-coding region. Mol Cell Biol. 1986; (1): 15-25
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