Cancer Institute A national cancer institute
designated cancer center
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Anthony Oro MD/PhD

Academic Appointments

  • Professor of Dermatology

Contact Information

  • Clinical Offices
    Adult Dermatology Clinic 450 Broadway St Pavilion B MC 5334 Redwood City, CA 94063
    Tel Work (650) 723-6316 Fax (650) 721-3476
  • Academic Offices
    Personal Information
    Email Tel (650) 723-7843
    Alternate Contact
    Daniel Braslavsky Administrative Assistant Tel Work 650-725-7022
    Not for medical emergencies or patient use

Professional Overview

Clinical Focus

  • Cancer> Cutaneous (Dermatologic) Oncology
  • Dermatology
  • Skin Cancer
  • Hair disorders
  • Genetic Skin Disease

Professional Education

Residency: Stanford University Medical Center CA (1997)
Board Certification: Dermatology, American Board of Dermatology (1998)
Internship: Stanford University Medical Center CA (1994)
Medical Education: UCSD School of Medicine CA (1993)

Courses

2013-14

Scientific Focus

Current Research and Scholarly Interests

Our lab studies skin stem cells to understand mechanisms of tissue regeneration and carcinogenesis. We have a longstanding interest in the mechanisms of Sonic hedgehog (Shh) signaling in the hair follicle and n the pathogenesis of the most common human tumor, basal cell carcinoma (BCCs) of the skin. We have provided clinical evidence for the first hedgehog pathway inhibitor and are developing novel targets for next generation inhibitors that target the transcription factor Gli. We are studying the mechanisms of tumor evolution and the development of chemoresistance to targeted agents in both patients and mouse models using genomics and bioinformatic methods followed by functional validation.

We are also interested in the mechanisms of human skin development and early ectodermal differentiation and have developed in vitro human skin differentiation from embryonic stem cells. Using this system, we are exploring how early ectoderm commits to stratified epithelium. We have used our system, in collaboration with other labs at Stanford, to manufacture corrected human epidermal sheets from patient-specific iPS cells.

Publications

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