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Amato J. Giaccia

Academic Appointments

  • Jack, Lulu and Sam Willson Professor, Professor of Radiation Oncology, and by courtesy, of Obstetrics and Gynecology and of Surgery

Contact Information

  • Academic Offices
    Personal Information
    Email Tel (650) 723-7366
    Alternate Contact
    Sharon Clarke Administrative Associate Tel Work 650.723.7311


Professor of Radiation Oncology, Associate Chair for Research & Director of the Division of Radiation & Cancer Biology in the Department of Radiation Oncology. He also heads the Radiation Biology Program in Stanford’s Cancer Center, and is Director of the Cancer Biology Interdisciplinary Graduate Program. Professor Giaccia was awarded an American Cancer Society Junior Faculty Research Award and the Michael Fry Award from the Radiation Research Society for his outstanding contributions on understanding the molecular mechanisms of resistance promoted by the tumor microenvironment. Additionally, he was the recipient of the 2013 ASTRO Gold Medal. Professor Giaccia has co-authored the sixth & seventh editions of the textbook, “Radiation Biology for the Radiologist,” with Professor Eric Hall from Columbia. In addition, he is currently the “Jack, Lulu and Sam Willson Professor in Cancer Biology” at Stanford University School of Medicine.

Academic Appointments

Administrative Appointments

  • Associate Director for Basic Science, Stanford Cancer Institute (2012 - present)
  • Associate Chair, Research, Department of Radiation Oncology, Stanford University School of Medicine (2011 - present)
  • Leader, Molecular Therapeutics Program, Stanford Cancer Center (2011 - present)

Honors and Awards

  • ASTRO Gold Medal, American Society of Therapeutic Radiology and Oncology (2013)
  • MERIT Award, NIH (2010)
  • Jack, Lulu and Sam Willson Endowed Professor of Cancer Biology, Stanford University (2006)
  • Virginia Logan Lecture, Thomas Jefferson University (2003)
  • John Yuhas Award (Excellence in Radiation Oncology, University of Pennsylvania), University of Pennsylvania (2000)
  • Michael Fry Research Awardee of the Radiation Research Society, Radiation Research Society (1997)
View All 8honors and awards of Amato Giaccia

Boards, Advisory Committees, Professional Organizations

  • Editorial Board Member, International Journal of Radiation Biology (1995 - 2000)
  • Associate Editor, International Journal of Radiation Biology (2000 - 2009)
  • Associate Editor, Radiation Research, Official Journal of the Radiation Research Society (1998 - 2002)
  • Editorial Board, International Journal of Radiation Oncology, Biology, Physics (2000 - present)
  • Foreign Associate Editor, Journal of Radiation Research, Official Journal of the Japan Radiation Research Society (2004 - present)
  • Associate Editor, Cancer Biology and Therapy (2001 - present)
View All 9professional activities and affiliations of Amato Giaccia

Professional Education

Ph.D.: University of Pennsylvania, Pathology/Molecular Biology (1989)
B.A.: Lafayette College, Biology (1980)

Research & Scholarship

Current Research and Scholarly Interests

During the last five years, we have identified several small molecules that acted to kill VHL deficient renal cancer cells through a synthetic lethal screening approach. We published on one of the molecules (Cancer Cell 14: 90, 2008) that killed VHL deficient tumor and are performing screens to identify new therapeutics against other targets. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We have identified and characterized several genes that are induced by hypoxia and promote metastases in breast, ovarian, renal and head and neck cancer (Nature 440:1222, 2006, Cancer Cell 15:35, 2009) and are developing therapeutics against them. My group is also investigating how hypoxia regulates gene expression epigenetically through the regulation of histone demethylases and microRNAs.


Graduate and Fellowship Program Affiliations



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