Cancer Institute A national cancer institute
designated cancer center

Don Goffinet

Publication Details

  • Plasmablastic lymphoma presenting in a human immunodeficiency virus-negative patient: a case report.

    Nguyen DD, Loo BW, Tillman G, Natkunam Y, Cao TM, Vaughan W, Dorfman RF, Goffinet DR, Jacobs CD, Advani RH. Ann Hematol. 2003; 82 (8): 521-5

    Plasmablastic lymphoma (PBL), an aggressive non-Hodgkin's lymphoma that carries a poor prognosis, previously has been identified almost exclusively in patients infected with the human immunodeficiency virus (HIV). We present a case of a 42-year-old HIV-negative patient presenting with an isolated nasal cavity mass, the typical presentation for PBL. The patient was given systemic chemotherapy, central nervous system prophylaxis, and consolidative locoregional radiotherapy and achieved a complete clinical response. This case suggests PBL should be considered in HIV-negative patients with characteristic findings.

    PubMedID: 12783213

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