Joseph Shrager
Publication Details
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Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema.
Respir Res. 2003: 1
Several physiological adaptations occur in the respiratory muscles in rodent models of elastase-induced emphysema. Although the contractile properties of the diaphragm are altered in a way that suggests expression of slower isoforms of myosin heavy chain (MHC), it has been difficult to demonstrate a shift in MHCs in an animal model that corresponds to the shift toward slower MHCs seen in human emphysema.
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