Billy W. Loo, Jr., MD, PhD, DABR
Publication Details
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Hypofractionation results in reduced tumor cell kill compared to conventional fractionation for tumors with regions of hypoxia.
Int J Radiat Oncol Biol Phys. 2011; (4): 1188-95
Tumor hypoxia has been observed in many human cancers and is associated with treatment failure in radiation therapy. The purpose of this study is to quantify the effect of different radiation fractionation schemes on tumor cell killing, assuming a realistic distribution of tumor oxygenation.
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