Russ B. Altman
Publication Details
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Estimation of the warfarin dose with clinical and pharmacogenetic data.
N Engl J Med. 2009; (8): 753-64
Genetic variability among patients plays an important role in determining the dose of warfarin that should be used when oral anticoagulation is initiated, but practical methods of using genetic information have not been evaluated in a diverse and large population. We developed and used an algorithm for estimating the appropriate warfarin dose that is based on both clinical and genetic data from a broad population base.
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