Matthew Bogyo
Publication Details
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Use of activity-based probes to develop high throughput screening assays that can be performed in complex cell extracts.
PLoS One. 2010; (8): e11985
High throughput screening (HTS) is one of the primary tools used to identify novel enzyme inhibitors. However, its applicability is generally restricted to targets that can either be expressed recombinantly or purified in large quantities.
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