Publication Details

Transcriptional programs activated by exposure of human prostate cancer cells to androgen.

DePrimo SE, Diehn M, Nelson JB, Reiter RE, Matese J, Fero M, Tibshirani R, Brown PO, Brooks JD. Genome Biol. 2002; 3 (7): RESEARCH0032

Androgens are required for both normal prostate development and prostate carcinogenesis. We used DNA microarrays, representing approximately 18,000 genes, to examine the temporal program of gene expression following treatment of the human prostate cancer cell line LNCaP with a synthetic androgen.

PubMedID: 12184806