George Triadafilopoulos
Publication Details
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Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma.
Gastroenterology. 2006; (3): 925-33
Barrett's esophagus is a precursor of esophageal adenocarcinoma. DNA microarrays that enable a genome-wide assessment of gene expression enhance the identification of specific genes as well as gene expression patterns that are expressed by Barrett's esophagus and adenocarcinoma compared with normal tissues. Barrett's esophagus length has also been identified as a risk factor for progression to adenocarcinoma, but whether there are intrinsic biological differences between short-segment and long-segment Barrett's esophagus can be explored with microarrays.
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