Cancer Institute A national cancer institute
designated cancer center

Quynh-Thu Le

Publication Details

  • Nonsurgical therapy for stages I and II non-small cell lung cancer.

    Le QT, Petrik DW. Hematol Oncol Clin North Am. 2005; 19 (2): 237-61, v-vi

    For patients who have stages I and II non-small cell lung cancer (NSCLC) and who are unable or unwilling to undergo surgical resection, nonsurgical treatment modalities have been used with curative intent. Conventionally fractionated radiotherapy has been the mainstay of nonsurgical therapy; however, advances in technology and the clinical application of radiobiologic principles have allowed more accurately targeted treatment that delivers higher effective doses to the tumor, while respecting the tolerance of surrounding normal tissues. This article discusses nonsurgical approaches to the treatment of early-stage NSCLC, including several promising techniques, such as radiation dose escalation, altered radiation fractionation, stereotactic radiotherapy, and radiofrequency ablation.

    PubMedID: 15833405

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