Cancer Institute A national cancer institute
designated cancer center

Philip W. Lavori

Publication Details

  • Psychiatric disorder in adolescent offspring of parents with affective disorder in a non-referred sample.

    Beardslee WR, Keller MB, Lavori PW, Klerman GK, Dorer DJ, Samuelson H. J Affect Disord. 1988 Nov-Dec; 15 (3): 313-22

    The relationship between parental psychopathology and psychiatric disturbance in 153 offspring aged 6-19 was assessed in 81 families randomly selected from a prepaid health plan. Offspring of parents with a history of affective disorders and of parents with non-affective psychiatric disorders had higher rates of psychiatric diagnoses and poorer adaptive functioning than children of parents who had never experienced a psychiatric illness. Offspring whose parents had affective disorder had a rate of affective disorder of 30% compared to a rate of 2% in the rest of the sample. This relationship between parental affective disorder and poor child outcome was observed when the separated and divorced families were removed from the analyses.

    PubMedID: 2975303

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