Cancer Institute A national cancer institute
designated cancer center

Esther M. John

Publication Details

  • Prostate cancer in African-American men and polymorphism in the calcium-sensing receptor.

    Schwartz GG, John EM, Rowland G, Ingles SA. Cancer Biol Ther. 2010; 9 (12): 994-9

    Prospective epidemiologic studies indicate that the risk for advanced prostate cancer is increased among men with high levels of serum calcium. Because serum calcium levels are influenced by the calcium-sensing receptor (CaSR), we examined prostate cancer in African-American men in relation to three single nucleotide polymorphisms (SNPs) in the CaSR gene, A986S, R990G and Q1011E. This is the first study of CaSR polymorphisms and risk of prostate cancer.

    PubMedID: 20364112

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