Dean W. Felsher
Publication Details
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Myc and a Cdk2 senescence switch.
Nat Cell Biol. 2010; (1): 7-9
Cdk2 has been shown to have an unanticipated role in suppressing Myc-induced senescence. This has implications for how c-Myc overcomes failsafe mechanisms to induce tumorigenesis and suggests that the inhibition of Cdk2 may have therapeutic efficacy in the treatment of cancer.
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