John Boothroyd
Publication Details
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Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes.
Nature. 1984 Sep 27-Oct 3; (5984): 350-5
The repeated mini-exon sequence that encodes the first 35 base pairs of all variant surface antigen mRNAs of Trypanosoma brucei directs the synthesis of a discrete 137-nucleotide transcript. It thus seems that variant surface antigen mRNAs are transcribed discontinuously, and we present two alternative models for how this might occur.
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