Dean W. Felsher
Publication Details
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Cancer revoked: oncogenes as therapeutic targets.
Nat Rev Cancer. 2003; (5): 375-80
Recent findings show that even the brief inactivation of a single oncogene might be sufficient to result in the sustained loss of a neoplastic phenotype. It is therefore possible that the targeted inactivation of oncogenes could be a specific and effective treatment for cancer. So why does oncogene inactivation cause tumour regression and will this be a generally successful approach for the treatment of human neoplasia?
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