Cancer Institute– A national cancer institute
designated cancer center

Ann M. Arvin

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Publication Details

  • Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections.

    Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Corey L, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M, Arvin AM, Gutierrez K, Shelton M, Weiner LB, Sleasman JW, de Sierra TM, Weller S, Soong SJ, Kiell J, Lakeman FD, Whitley RJ. Pediatrics. 2001; 108 (2): 230-8

    The objective of this investigation was to establish the safety of high-dose (HD) acyclovir for the treatment of neonatal herpes simplex virus (HSV) disease. In addition, an estimate of therapeutic efficacy was sought, both with respect to mortality and to morbidity. Virologic efficacy of HD acyclovir was also assessed.

    PubMedID: 11483782

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