Susan Knox
Publication Details
-
Tumor-selective killing by selenite in patient-matched pairs of normal and malignant prostate cells.
Prostate. 2006; (2): 218-25
Selenium compounds have been shown to induce apoptosis in a variety of human prostate cancer cell lines. However, the effects of selenium have yet to be examined in normal and malignant cells derived from the same individual. Selenite metabolism consumes glutathione (GSH) and produces superoxide. The generation of reactive oxygen species is an important mechanism in selenite-induced apoptosis.
Help
Trial Administration