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Daniel Bernstein

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Publication Details

  • Genotypic variation and phenotypic characterization of granzyme B gene polymorphisms.

    Girnita DM, Webber SA, Brooks MM, Ferrell R, Girnita AL, Burckart GJ, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, Naftel D, Zeevi A. Transplantation. 2009; 87 (12): 1801-6

    Granzyme B has been associated with allograft rejection in solid organ transplantation. Single nucleotide polymorphisms (SNPs) in the granzyme B gene might impact its expression. The aims of this study were (1) to establish the frequency of two granzyme B SNPs (A-295G; Q-55R) in pediatric heart transplant (PHTx) recipients and (2) to determine their phenotypic expression in healthy individuals.

    PubMedID: 19543056

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