Cancer Institute A national cancer institute
designated cancer center

Patrick O. Brown

Publication Details

  • A gene-expression program reflecting the innate immune response of cultured intestinal epithelial cells to infection by Listeria monocytogenes.

    Baldwin DN, Vanchinathan V, Brown PO, Theriot JA. Genome Biol. 2003; 4 (1): R2

    Listeria monocytogenes is a Gram-positive, facultative, intracellular bacterial pathogen found in soil, which occasionally causes serious food-borne disease in humans. The outcome of an infection is dependent on the state of the infected individual's immune system, neutrophils being key players in clearing the microorganism from the body. The first line of host defense, however, is the intestinal epithelium.

    PubMedID: 12537547

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