Anthony Oro MD/PhD
Publication Details
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The primary cilia, a 'Rab-id' transit system for hedgehog signaling.
Curr Opin Cell Biol. 2007; (6): 691-6
Intense focus has been centered around how the primary cilia transduces the hedgehog (Hh) signal from smoothened (Smo) to the Gli transcription factors. New data indicate that ligand and signaling lipids help regulate small GTPase-dependent accumulation and activity of signaling components.
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