Philip W. Lavori
Publication Details
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Improving the efficiency of estimation in randomized trials of adaptive treatment strategies.
Clin Trials. 2007; (4): 297-308
Given the history of treatments to date, and the responses of the patient, what is the best treatment to try next? An ensemble of sequential, multistage rules guiding such adaptive decision making can be described as an ;adaptive treatment strategy (ATS)'. Robins' G-computation can be used for estimation of the mean outcome of an ATS from a ;sequential multiple assignment randomized (SMAR)' trial.
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