Jonathan S. Berek
Publication Details
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Ovarian cancer screening. The use of serial complementary tumor markers to improve sensitivity and specificity for early detection.
Cancer. 1995; (10 Suppl): 2092-6
The use of serum tumor markers for the early detection of ovarian cancer has been limited because of their low sensitivity and low positive predictive value. CA 125 levels are elevated in only about one half of women with Stage I ovarian cancer, thus researchers have focused on using the serial measurement of complementary markers to improve the sensitivity, specificity, and positive predictive value of this approach for screening.
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