Cancer Institute A national cancer institute
designated cancer center

John Boothroyd

Publication Details

  • Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini.

    Boothroyd JC, Paynter CA, Cross GA, Bernards A, Borst P. Nucleic Acids Res. 1981; 9 (18): 4735-43

    cDNAs coding for the amino and carboxy termini of two trypanosome variant surface glycoproteins (VSGs) have been sequenced. The results indicate that VSGs are synthesised with hydrophobic amino-terminal leader and carboxy-terminal tail sequences which are absent from purified mature VSGs.

    PubMedID: 6272213

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