Publication Details

Reduction of iron stores and cardiovascular outcomes in patients with peripheral arterial disease: a randomized controlled trial.

Zacharski LR, Chow BK, Howes PS, Shamayeva G, Baron JA, Dalman RL, Malenka DJ, Ozaki CK, Lavori PW. JAMA. 2007; 297 (6): 603-10

Accumulation of iron in excess of physiologic requirements has been implicated in risk of cardiovascular disease because of increased iron-catalyzed free radical-mediated oxidative stress.

PubMedID: 17299195