Esther M. John
Publication Details
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Genetic ancestry and risk factors for breast cancer among Latinas in the San Francisco Bay Area.
Cancer Epidemiol Biomarkers Prev. 2006; (10): 1878-85
Genetic association studies using case-control designs are susceptible to false-positive and false-negative results if there are differences in genetic ancestry between cases and controls. We measured genetic ancestry among Latinas in a population-based case-control study of breast cancer and tested the association between ancestry and known breast cancer risk factors. We reasoned that if genetic ancestry is associated with known breast cancer risk factors, then the results of genetic association studies would be confounded.
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