Holbrook Kohrt
Publication Details
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Cytotoxic T lymphocyte responses against melanocytes and melanoma.
J Transl Med. 2011; (1): 122
Vitiligo is a common toxicity associated with immunotherapy for melanoma. Cytotoxic T lymphocytes (CTLs) against melanoma commonly target melanoma-associated antigens (MAAs) which are also expressed by melanocytes. To uncouple vitiligo from melanoma destruction, it is important to understand if CTLs can respond against melanoma and melanocytes at different levels.
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