Publication Details

Analysis of phase II studies on targeted agents and subsequent phase III trials: what are the predictors for success?

Chan JK, Ueda SM, Sugiyama VE, Stave CD, Shin JY, Monk BJ, Sikic BI, Osann K, Kapp DS. J Clin Oncol. 2008; 26 (9): 1511-8

To identify the characteristics of phase II studies that predict for subsequent "positive" phase III trials (those that reached the proposed primary end points of study or those wherein the study drug was superior to the standard regimen investigating targeted agents in advanced tumors.

PubMedID: 18285603