Publication Details

Non-damaging retinal phototherapy: dynamic range of heat shock protein expression.

Sramek C, Mackanos M, Spitler R, Leung LS, Nomoto H, Contag CH, Palanker D. Invest Ophthalmol Vis Sci. 2011; 52 (3): 1780-7

Subthreshold retinal phototherapy demonstrated clinical efficacy for the treatment of diabetic macular edema without visible signs of retinal damage. To assess the range of cellular responses to sublethal hyperthermia, expression of the gene encoding a 70 kDa heat shock protein (HSP70) was evaluated after laser irradiation using a transgenic reporter mouse.

PubMedID: 21087969