Department: Cancer Center

Division: Radiation Biology

• Faculty (29)
• Postdocs (0)
• All

• 
  Attardi, Laura 
  Academic Appointments

  • Associate Professor, Radiation Oncology - Radiation Biology
  • Associate Professor, Genetics
  • Member, Bio-X
  • Member, Cancer Center
  Research Interest

  Our research is aimed at defining the pathways of p53-mediated apoptosis and tumor suppression, using a combination of biochemical, cell biological, and mouse genetic approaches. Our strategy is to start by generating hypotheses about p53 mechanisms of action using primary mouse embryo fibroblasts (MEFs), and then to test them using gene targeting technology in the mouse.

• 
  Bouley, Donna 
  Academic Appointments

  • Professor - Med Center Line, Comparative Medicine
  • Professor - Med Center Line (By courtesy), Pathology
  • Member, Cancer Center
  Research Interest

  Research interests: ocular pathology, host-pathogen interactions in infectious disease, infectious disease in frogs, phenotypic characterization of tg and ko mice, histopathology of minimally-invasive radiological ablation techniques (focused ultrasound, cryoablation).

• 
  Brown, Martin 
  Academic Appointments

  • Professor, Radiation Oncology - Radiation Biology
  • Member, Cancer Center
  Research Interest

  We seek to understand the mechanisms responsible for the resistance of cancers to treatment and to develop strategies to overcome these resistances. We are using molecular and cellular techniques and mouse models to exploit tumor hypoxia with drugs activated by hypoxia and anaerobic bacteria as tumor-specific gene therapy vectors. We are also testing ways of inhibiting the bone marrow rescue of the tumor vasculature following therapy.

• 
  Cappelli, Mark 
  Academic Appointments

  • Member, Cancer Center
• 
  Cochran, Jennifer 
  Academic Appointments

  • Assistant Professor, Bioengineering
  • Member, Bio-X
  • Member, Cancer Center
  Research Interest

  Molecular Bioengineering, Protein Biochemistry and Biotechnology, Cell and Tissue Engineering, Molecular Imaging

• 
  Cornfield, David 
  Academic Appointments

  • Professor, Pediatrics - Pulmonary Medicine
  • Member, Cancer Center
  Clinical Focus

  • Pediatric Pulmonary
  • Pulmonary Medicine/Cystic Fibrosis, Pediatric
  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Denko, Nicholas 
  Academic Appointments

  • Assistant Professor, Radiation Oncology - Radiation Biology
  • Member, Cancer Center
  Research Interest

  We are interested in the biologic effect of gene expression changes that occur in the solid tumor. Many of these expression changes are due to the micro-physiology within the tumor. Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention. We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes.

• 
  Donaldson, Sarah 
  Academic Appointments

  • Professor, Radiation Oncology - Radiation Therapy
  • Member, Cancer Center
  Clinical Focus

  • Basal / Squamous Cell Carcinomas - Radiation Oncology
  • Bone Cancer
  • Brain / Central Nervous System Tumors
  Research Interest

  Combined Modality Treatment of Cancer Late Effects of Treatment Genetic Effects of Cancer Rhabdomyosarcoma Hodgkins Disease Pediatric Radiation Oncolgy Pediatric Oncolgy Breast Cancer Conformal Radiotherapy/IMRT Radiotherapy for Benign Diseases

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Ford, James 
  Academic Appointments

  • Associate Professor, Medicine - Oncology
  • Associate Professor, Genetics
  • Associate Professor (By courtesy), Pediatrics
  • Member, Bio-X
  • Member, Cancer Center
  Clinical Focus

  • Cancer Genetics
  • Gastrointestinal Cancers - Genetics
  • Gastrointestinal Cancers - Medical Oncology
  Research Interest

  Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNAdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Giaccia, Amato 
  Academic Appointments

  • Professor, Radiation Oncology - Radiation Biology
  • Professor (By courtesy), Obstetrics & Gynecology
  • Professor (By courtesy), Surgery
  • Member, Cancer Center
  Research Interest

  Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.

• 
  Gibbs, Iris 
  Academic Appointments

  • Associate Professor - Med Center Line, Radiation Oncology - Radiation Therapy
  • Member, Cancer Center
  Clinical Focus

  • Cyberknife
  • Brain / Central Nervous System Tumors - Radiation Oncology
  • Acoustic Neuroma
  Research Interest

  Dr. Gibbs is a board-certified radiation oncologist who specializes in the treatment of CNS tumors. Her research focuses on developing new radiation techniques to manage brain and spinal tumors in adults and children. Dr. Gibbs has gained worldwide acclaim for her expertise in Cyberknife robotic radiosurgery.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Graves, Edward 
  Academic Appointments

  • Assistant Professor, Radiation Oncology - Radiation Physics
  • Member, Cancer Center
  Research Interest

  Applications of molecular imaging in radiation therapy, development of hypoxia and radiosensitivity imaging techniques, image processing and analysis.

• 
  Gurtner, Geoffrey C
  Academic Appointments

  • Professor - Med Center Line, Surgery - Plastic/Recon Surgery
  • Member, Cancer Center
  Clinical Focus

  • Plastic Surgery
  Research Interest

  Geoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Hanawalt, Philip C
  Academic Appointments

  • Professor, Biology (School of Humanities and Sciences)
  • Professor, Dermatology
  • Member, Bio-X
  • Member, Cancer Center
  Research Interest

  Hanawalt has been a productive researcher in the field of DNA repair since his pioneering discovery of repair replication in E. coli in 1963. He also first demonstrated repair replication in mycoplasmata and in a eukaryote and he has developed a number of important experimental approaches for studying repair, beginning with the BrdUrd density labeling method for resolving semiconservatively replicated DNA from parental DNA containing repair patches. Hanawalt’s approach was used to validate the ..

• 
  Hoppe, Richard 
  Academic Appointments

  • Professor, Radiation Oncology - Radiation Therapy
  • Member, Cancer Center
  Clinical Focus

  • Lymphoma
  • Cutaneous Lymphoma
  • Cutaneous Lymphoma - Radiation Oncology
  Research Interest

  Irradiation immunosuppression; total body irradiation;, psychosocial effects of cancer treatment; treatment of lymphoma;, mycosis fungoides.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Kapp, Daniel 
  Academic Appointments

  • Professor, Radiation Oncology - Radiation Therapy
  • Member, Cancer Center
  Clinical Focus

  • Brain / Central Nervous System Tumors
  • Brain / Central Nervous System Tumors - Radiation Oncology
  • Breast Cancer
  Research Interest

  Gynecologic malignancies; Rectal/and cancer; Breast Cancer; Hodgkin's disease; Hyperthermia; intraoperative radiation therapy; High dose rate radiation therapy; Predictive assays; Patterns of tumor spread; Health care finance.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  King, Christopher 
  Academic Appointments

  • Member, Cancer Center
  Research Interest

  Prostate cancer

• 
  Knox, Susan 
  Academic Appointments

  • Associate Professor, Radiation Oncology - Radiation Therapy
  • Member, Bio-X
  • Member, Cancer Center
  Clinical Focus

  • Radiation Oncology
  • Radiation Therapy
  Research Interest

  Our interests in clude 1) study of the effect of radiation on regulatory cell subpopulations and co-stimulatory molecules, 2) use of radiation as an immune modulator for optimization of transplant regimens, and 3) the role of radiation in tumor vaccine strategies.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Koong, Albert 
  Academic Appointments

  • Assistant Professor, Radiation Oncology - Radiation Therapy
  • Member, Bio-X
  • Member, Cancer Center
  Clinical Focus

  • Colorectal Cancer
  • Colorectal Cancer - Radiation Oncology
  • Esophageal Cancer
  Research Interest

  The focus of my laboratory is to understand the role of hypoxia and the tumor microenvironment on malignant progression. My clinical area of interest is in the application of chemoradiotherapy and stereotactic radiosurgery for GI maligancies

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Lazzeroni, Laura 
  Academic Appointments

  • Associate Professor (Research), Psychiatry & Behavioral Science
  • Associate Professor (Research), Pediatrics
  • Member, Bio-X
  • Member, Cancer Center
• 
  Le, Quynh-Thu 
  Academic Appointments

  • Professor - Med Center Line, Radiation Oncology - Radiation Therapy
  • Professor - Med Center Line (By courtesy), Otolaryngology (Head and Neck Surgery)
  • Member, Bio-X
  • Member, Cancer Center
  Clinical Focus

  • Head and Neck Cancers
  • Head and Neck Cancers - Radiation Oncology
  • Larynx Cancer
  Research Interest

  My laboratory research interest focusses on the identification of serum markers for tumor hypoxia and for prognosis in patients with head and neck or lung cancers. I am also conducting a number of clinical trials specifically in patients with these tumors.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Longaker, Michael 
  Academic Appointments

  • Professor, Surgery - Plastic/Recon Surgery
  • Professor (By courtesy), Bioengineering
  • Member, Bio-X
  • Member, Cancer Center
  Clinical Focus

  • Plastic Surgery
  • Plastic Surgery, Pediatric
  Research Interest

  We have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2)Distraction Osteogenesis, 3) Cleft Palate and Lip Biology, 4)Keloid and Hypertrophic Scar Biology, 5) Scarless Fetal Wound Healing, 6) Novel Gene and Stem Cell Therapeutic Approaches.

  Practices at Lucile Packard Children's Hospital
• 
  Loo, Billy 
  Academic Appointments

  • Acting Assistant Professor, Radiation Oncology - Radiation Therapy
  • Member, Bio-X
  • Member, Cancer Center
  Clinical Focus

  • Radiation Oncology
  • Radiation Therapy
  • Lung Cancer
  Research Interest

  My main clinical specialties are radiation treatment of lung cancer and head & neck cancer, and I serve as the thoracic radiation oncology program leader. My research interests include 4-D multimodality imaging to capture and compensate for breathing-induced motion using CT, PET, and MR; novel functional/metabolic imaging methods to characterize tumor biology; high-precision image-guided radiation therapy including 4-D IMRT, dynamic arc therapy, and radiosurgery.

  Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
• 
  Mitchell, Beverly S
  Academic Appointments

  • Professor, Medicine - Oncology
  • Professor (By courtesy), Chemical and Systems Biology
  • Member, Cancer Center
  Clinical Focus

  • Hematology
  Research Interest

  Beverly Mitchell's research relates to the development of new therapies for hematologic malignancies. She has a long-standing interest in IMPDH as a therapeutic target and has published extensively on the regulation of this enzyme and the potential role of inhibitors in the treatment of leukemia in preclinical studies.

• 
  Morrison, Ashby 
  Academic Appointments

  • Assistant Professor, Biology (School of Humanities and Sciences)
  • Member, Cancer Center
  Research Interest

  Our research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity.

• 
  Peehl, Donna 
  Academic Appointments

  • Professor (Research), Urology
  • Member, Bio-X
  • Member, Cancer Center
  Research Interest

  My research focuses on the molecular and cellular biology of the human prostate. Developing realistic experimental models is a major goal, and primary cultures of prostatic epithelial and stromal cells are my main model system. Our discoveries are relevant to prevention, detection, diagnosis and treatment of benign and malignant prostatic diseases.

• 
  Smitt, Melanie 
  Academic Appointments

  • Member, Cancer Center
  Research Interest

  Breast cancer; three-dimensional treatment planning; community patterns of care and technology transfer.

• 
  Tibshirani, Robert 
  Academic Appointments

  • Professor, Health Research & Policy - Biostatistics
  • Professor, Statistics
  • Member, Bio-X
  • Member, Cancer Center
  Research Interest

  My research is in applied statistics and biostatistics. I specialize in computer-intensive methods for regression and classification, bootstrap, cross-validationand statistical inference, and signal and image analysis for medical diagnosis.

• 
  Xing, Lei 
  Academic Appointments

  • Professor, Radiation Oncology - Radiation Physics
  • Member, Bio-X
  • Member, Cancer Center
  Research Interest

  Image-guided intervention, MR spectroscopic imaging (MRSI) and radionuclide imaging (PET/CT, SPECT/CT), biologically conformable radiation threapy (BCRT), intensity modulated radiation therapy (IMRT), treatment plan optimization, optimization of stereotactic radiosurgery, image segmentation and deformable image registration, application of molecular imaging to radiation oncology.