Cancer Institute A national cancer institute
designated cancer center

Department: Stanford Cancer Institute

S

  • Associate Professor of Pediatrics (Cancer Biology) and of Genetics
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Faculty Fellow, Stanford ChEM-H
    Research Interest

    We are interested in the links between the basic cell cycle machinery and the factors controlling self-renewal, differentiation, and regeneration. In particular, we are intrigued by the differences and the similarities between "normal" cells, cancer cells, and stem cells. We investigate the mechanisms by which normal cells become tumor cells, and we aim to understand the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells.

  • Shelagh Galligan Professor in the School of Medicine
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Faculty Fellow, Stanford ChEM-H
    Clinical Focus
    • Pediatric Hematology-Oncology
    Research Interest

    My research focuses on the molecular pathways that regulate normal and aberrant blood cell development, including acute leukemia and bone marrow failure syndromes. We are also studying novel drugs for treatment of cancer.

  • Assistant Professor of Biochemistry
    Member, Bio-X
    Member, Stanford Cancer Institute
  • Professor of Microbiology and Immunology
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Research Interest

    Our laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.

  • Associate Professor of Biology and of Applied Physics
    Member, Bio-X
    Member, Stanford Cancer Institute
    Member, Stanford Neurosciences Institute
    Research Interest

    My laboratory has three major research efforts:
    1) In vivo fluorescence imaging and behavioral studies of cerebellar-dependent motor control and motor learning.
    2) Development and application of fiber-optic fluorescence microendoscopy imaging techniques for studies of learning and memory in behaving mice and for clinical uses in humans.
    3) Development of high-throughput, massively parallel imaging techniques for studying brain function in large numbers of Drosophila concurrently.

  • Professor of Medicine (Infectious Diseases), Emeritus
    Member, Stanford Cancer Institute
    Faculty Fellow, Stanford ChEM-H
    Clinical Focus
    • Infectious Disease
    • Infectious Diseases
    Research Interest

    Structure-function analysis of bacterial adhesion proteins and toxins; design and synthesis of synthetic antigens; immunobiology of human papillomaviruses

  • Professor of Medicine (Hematology), Emeritus
    Member, Stanford Cancer Institute
    Clinical Focus
    • Hematology
    • Hematology  > Leukemia - Acute and Chronic
    • Hematology
  • Professor of Pathology and, by courtesy, of Pediatrics (Genetics) at the Stanford University Medical Center
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Clinical Pathology
    • Molecular Genetic Pathology
    Research Interest

    Iris Schrijver is a diplomate of the ABMG, with specialty certification in Clinical Molecular Genetics. In addition, she is a diplomate of the ABP in Clinical Pathology. She is one of the directors of the diagnostic Molecular Pathology laboratory and Stanford Point-of-Care testing. Research interests include the characterization of the molecular basis of inherited disorders, genotype-phenotype correlations, and development of novel molecular diagnostic tools.

  • Howard H. and Jessie T. Watkins University Professor and Professor of Genetics, Bioengineering and, by courtesy, of Biology
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Faculty Fellow, Stanford ChEM-H
    Member, Stanford Neurosciences Institute
    Research Interest

    Our research is focused on the genetic regulation of animal development and its relation to birth defects, cancer, and neurodegeneration. We study mechanisms and functions of Hedgehog (Hh) signaling, which controls cell fates and growth, in the context of normal development and brain cancer. We study a neurodegenerative disease, Niemann-Pick C syndrome, that affects intracellular organelle movements and sterol homeostasis.

  • Clinical Focus
    • GI Oncology
    • Rectal Cancer
    • Colon and Rectal Surgery
    Research Interest

    Multimodality treatment of rectal cancer
    Sphincter preserving procedures for rectal cancer
    Laparoscopic colon and rectal surgery
    Surgical education

  • Associate Professor of Genetics
    Member, Stanford Cancer Institute
    Research Interest

    Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species

  • Assistant Professor of Health Research and Policy
    Member, Stanford Cancer Institute
  • Associate Professor of Medicine (Blood and Marrow Transplantation)
    Member, Stanford Cancer Institute
    Clinical Focus
    • Blood and Marrow Transplant
    • Blood and Marrow Transplantation
    • Hematology
    Research Interest

    Transplantation of defined populations of allogeneic hematopoietic cells. Specifically, the way in which hematopoietic cell grafts alter antigen specific immune responses to allo-, auto- and viral antigens. The cellular and molecular basis of resistance to engraftment of allogeneic hematopoietic stem cells.

  • Stanley McCormick Memorial Professor in the School of Medicine
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Affiliate, Stanford Woods Institute for the Environment
    Clinical Focus
    • Urology, Pediatric
    • Pediatric Urology
    • Hypospadias: one stage repairs
    Research Interest

    The timing for intervention in obstruction in the infant and child is poorly understood.Our group has been interested in trying to define the risks that may be involved in obstructive and infectious uropathies and discovering early signs of damage to the urinary tract and kidney. We have explored ways of imaging the urinary tract using nonionizing radiation (US, MRI). We have studied the relationships of sex steroid hormones, pregnancy, reflux, urinary tract infection and urinary tract function.

  • Professor of Cardiothoracic Surgery at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Thoracic Oncology
    • Thoracic Cancers - Thoracic Surgery
    • Thoracic Surgery
    Research Interest

    In clinical research, Dr. Shrager has been an innovator studying outcomes in a variety of areas within Thoracic Surgery including: parenchyma-sparing operations and minimally invasive resections for lung cancer, transcervical thymectomy for myasthenia gravis, and surgical treatment of emphysema.

    In the lab, Dr. Shrager is focused on the impact of disease states upon the diaphragm. His group published the seminal paper (NEJM) describing diaphragm atrophy assoc'd with mechanical ventilation.

  • Assistant Professor of Health Research and Policy
    Member, Stanford Cancer Institute
    Research Interest

    My research focuses on identifying molecular and epidemiologic factors underlying cancer susceptibility and outcomes in order to improve prevention, detection, and treatment. I am especially interested in hormone-related cancers including cancers of the breast, ovary, and prostate. I currently lead a study to identify genetic and modifiable lifestyle factors for mammographic breast density in 30,000 women participating in Kaiser’s Research Program on Genes, Environment and Health. I also act

  • Professor of Medicine (Oncology)
    Member, Stanford Cancer Institute
    Clinical Focus
    • Sarcoma
    • Medical Oncology
    • New Drug Studies
    Research Interest

    Research Interests: cancer pharmacology, mechanisms of resistance to anticancer drugs, regulation and function of MDR1 and tubulin genes, clinical trials of modulation of drug resistance, general oncology, Phase I trials of new drugs, gene expression profiling of cancers

  • Thomas A. Stamey Research Professor in Urology
    Member, Stanford Cancer Institute
    Clinical Focus
    • Urologic Oncology
    • Cancer > urologic oncology
    • Bladder Cancer
    Research Interest

    My research focuses on outcomes in the treatment of muscle invasive and high-grade non-muscle invasive bladder cancer. This includes identifying markers of prognosis, predictive markers for response to surgery and chemotherapy, and working toward an individualized, multidisciplinary approach to disease management. I have also focused on optimizing the use of lower urinary tract reconstruction in patients undergoing cystectomy, and developing interventions to improve patient quality of life.

  • Associate Professor of Neurosurgery at the Stanford University Medical Center
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • Neurological Surgery
    • Neurosurgery
    Research Interest

    My research focuses on screening strategies to identify and characterize cancer stem cells (CSCs) in human gliomas. We are pursuing this in several ways: 1) a novel colony-forming antibody live cell array to identify distinct CSC surface phenotypes, 2) RNAi screens to identify kinases critical for CSC tumorigenicity, 3) high throughput small molecule and chemical screens to identify compounds that selectively kill or target CSCs, and 4) identifying CSCs using the tumor specific EGFRvIII

  • Assistant Professor of Biology and, by courtesy, of Chemical and Systems Biology
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    A central aim of the burgeoning field of systems biology is to understand the principles governing genetic control networks. I believe finding the principles underlying genetic circuits will occur through detailed studies and then comparisons of several natural systems. Due to its extensive development as an experimental system, our favorite model, the budding yeast cell cycle, is poised to become central to this enterprise.

  • Professor of Medicine (Oncology) at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Breast Cancer
    • Medical Oncology
  • Professor of Molecular and Cellular Physiology, Emeritus
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    Research in the Smith Laboratory addresses basic mechanisms and and disorders of brain function. Present efforts are focused on the development and application of new proteomic imaging methods to explore the circuit and molecular architectures of memory storage and retrieval in cerebral cortex.

  • Stanford W. Ascherman, MD, FACS, Professor in Genetics
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Member, Stanford Neurosciences Institute
    Research Interest

    Our laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states

  • Lui Hac Minh Professor in the School of Medicine
    Member, Stanford Cancer Institute
    Clinical Focus
    • GI Oncology
    • Liver Cancer
    • Liver Cancer - Surgery
    Research Interest

    Through a 4 pronged comprehensive program: translational and clinical research, early detection and treatment, promoting education, awareness and immunization and building partnership, we are working towards the development of new strategies that will lead to the elimination of hepatitis B worldwide and reduce the threat and incidence of liver cancer. Current research efforts focus on evaluating potential new diagnostic and treatment markers and novel targeted therapy for primary liver cancer.

  • Assistant Professor of Radiation Oncology (Radiation Therapy) at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Radiation Oncology
    • Radiation Oncology
    • Radiosurgery
    Research Interest

    My clinical and research interests focus on the development of new radiation techniques involving stereotactic radiosurgery and radiotherapy for the treatment of malignant and benign tumors of the brain and spine, as well as functional disorders such as trigeminal neuralgia.

  • Professor of Radiology (General Radiology)
    Member, Stanford Cancer Institute
    Clinical Focus
    • Diagnostic Radiology
    • Radiology
    • abdominal imaging and uroradiology
    Research Interest

    Studies include development and preliminary clinical evaluation of advanced techniques for ultrasonic imaging and tissue characterization. A number of studies are ongoing involving advanced techniques of magnetic resonance imaging and spectroscopy with application to the GU tract.

  • Jack, Samuel and Lulu Willson Professor in Medicine
    Member, Stanford Cancer Institute
    Member, Stanford Neurosciences Institute
    Clinical Focus
    • Psychiatry
    • Psychiatry, Child and Adolescent
    • Medical Director, Stanford Center for Integrative Medicine
    Research Interest

    Dr. Spiegel's research program involves mind/body interactions, including cancer progression, the response to traumatic stress, and the effect of hypnosis on the perception of pain and anxiety.

  • Professor of Radiology (General Radiology) and, by courtesy, of Electrical Engineering
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    My research interests are in the field of medical imaging, particularly magnetic resonance imaging and in vivo spectroscopy. Current projects include MRI and MRS at high magnetic fields and metabolic imaging using hyperpolarized 13C-labeled MRS.

  • Douglass M. and Nola Leishman Professor of Cardiovascular Disease
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Research Interest

    The general research interest of this laboratory is the molecular basis of cell motility. We have three specific research interests, the molecular basis of energy transduction that leads to ATP-driven myosin movement on actin, the biochemical basis of the regulation of actin and myosin interaction and their assembly states, and the roles these proteins play in vivo, in cell movement and changes in cell shape.

  • Associate Professor of Medicine (Oncology) at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Urologic Oncology
    • Bladder Cancer
    • Bladder Cancer - Medical Oncology
    Research Interest

    Clinical interests: general oncology, genito-urinary malignancy Research interests: conducting clinical trials in advanced prostate cancer, bladder cancer and renal cell carcinoma

  • Professor of Medicine (Stanford Center for Research in Disease Prevention)
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Hyperlipidemia (high cholesterol)
    • Hypertension (high blood pressure)
    • Diabetes Mellitus
    Research Interest

    As Director of the SPRC Program on Prevention Outcomes and Practices, my work focuses on cardiovascular disease treatment and prevention, the adoption of new technology and practices, and patterns of physician practice, particularly medication prescribing. Specific interests include measuring and improving the quality of outpatient care, disparities in health care by race, gender, age and socioeconomic status, and interventions to improve prevention outcomes.

  • Professor (Research) of Medicine (Stanford Prevention Research Center) and of Obstetrics and Gynecology
    Member, Stanford Cancer Institute
    Research Interest

    Marcia Stefanick, Ph.D a Professor of Medicine at the Stanford Prevention Research Center, (SPRC) and Professor of Obstetrics and Gynecology, Stanford University School of Medicine.
    Dr. Stefanicks research focuses on chronic disease prevention (particularly, heart disease, breast cancer, osteoporosis, and dementia) in both women and men. Her work on the effects of menopausal hormones on cardiovascular and other health outcomes in mostly healthy postmenopausal women (in the Womens Health Initi

  • Maureen Lyles D'Ambrogio Professor in the School of Medicine, Emeritus
    Member, Stanford Cancer Institute
    Clinical Focus
    • Breast Cancer
    • Breast Cancer - Medical Oncology
    • Oncology
    Research Interest

    Laboratory and clinical research in breast cancer ; Normal and abornal differentiation and growth

  • Associate Professor of Biochemistry
    Member, Bio-X
    Member, Stanford Cancer Institute
    Faculty Fellow, Stanford ChEM-H
    Research Interest

    We study the process of cell division. Our research is focused on understanding how chromosomes are segregated during mitosis and how cells divide during cytokinesis.

  • Professor of Medicine (Immunology and Rheumatology)
    Member, Stanford Cancer Institute
    Clinical Focus
    • Immunology and Rheumatology
    • Rheumatology
    Research Interest

    Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation.

  • Associate Professor of Urology
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Research Interest

    We focus on understanding the molecular mechanism of transcription factors that govern the transformation of normal cells to a neoplastic state. We are especially interested in nuclear hormone action and its interactions with other signaling pathways in tumor development and progression.

  • Assistant Professor of Pathology and Dermatology at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Cutaneous (Dermatologic) Oncology
    • Pathology
    • Anatomic/Clinical Pathology
    Research Interest

    Broad study of extramedullary myeloid tumors; Characterization of CD30+ lymphoproliferative disorders and pathogenesis; Mutational analysis of CD30+ lymphoproliferative disorders; Characterization of cutaneous mast cell disease and distinction from systemic mastocytosis; Comparison of systemic and cutaneous B cell lymphomas by immunohistochemical profiles and the use of tissue microarrays; microRNA studies of cutaneous lymphomas

  • Assistant Professor of Otolaryngology - Head and Neck Surgery
    Member, Stanford Cancer Institute
    Clinical Focus
    • Cutaneous (Dermatologic) Oncology
    • Head and Neck Cancer
    • Thyroid Neoplasms
    Research Interest

    My laboratory is focused on two primary areas of research: (1) the immune response to head and neck cancer and to a tumorigenic population of cells within these malignancies called cancer stem cells; (2) the developmental programs of a special lymphocyte population involved in innate immunity called natural killer (NK) cells.

  • James H. Clark Professor in the School of Engineering and Professor of Chemical Engineering and of Bioengineering
    Member, Bio-X
    Member, Stanford Cancer Institute
    Faculty Fellow, Stanford ChEM-H
  • Associate Professor (Research) of Pediatrics (Cancer Biology)
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Pediatric Hematology-Oncology
    • clinical genomics
    • pediatric sarcomas
    Research Interest

    Our laboratory is devoted to the analysis of pathways involved in the initiation, progression, and maintenance of cancer. Utilizing the mouse as a model system, we strive to understand aberrant oncogenic signaling, the role of the tumor microenvironment and the mechanisms involved in chemotherapy response and resistance at the molecular, cellular, and organismal levels.

  • Professor of Dermatology at Palo Alto Veterans Affairs Health Care System and the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Cutaneous (Dermatologic) Oncology
    • Pigmented Skin Lesions
    • Melanoma
    Research Interest

    1) Early detection of melanoma through enhanced screening and professional and public education to improve melanoma awareness. 2) Chemoprevention of melanoma and nonmelanoma skin cancers in high-risk groups. 4) Epidemiologic and sociodemographic aspects of melanoma. 4) National dermatologist liaison to the ECOG-ACRIN Melanoma Committee and Co-founder/Co-Director of the Melanoma Prevention Working Group, an interdisciplinary Intergroup collaboration dedicated to melanoma control and prevent

  • Associate Professor of Surgery (Pediatric Surgery) and Pediatrics at the Stanford University Medical Center
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Surgery, Pediatric
    • Pediatric Surgery
    Research Interest

    One of the current primary interests of the lab is to investigate the mechanisms by which hepatocellular injury and recovery is influenced and controlled by hepatocyte metabolism.

    A second focus of investigation is to identify molecular markers of human disease that provide diagnostic function, serve as targets for possible therapeutic manipulation, or provide insight into mechanisms of human disease. Specific diseases of interest include newborn sepsis and Necrotizing Enterocolitis (NEC).

  • Professor of Radiology (General Radiology) at the Stanford University Medical Center
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • Interventional Radiology
    • Interventional Oncology
    Research Interest

    Transarterial administration of chemotherapeutics, radioactive microspheres, and biologics for the treatment of unresectable tumors; management of portal hypertension and complications of cirrhosis (TIPS); treatment of complications of organ transplantation; Venous and pulmonary arterial thrombolysis and reconstruction; Stent and Stent-graft treatment of peripheral vascular diseases, aneurysms, aortic dissections

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