Cancer Institute A national cancer institute
designated cancer center

Department: Stanford Cancer Institute

F

  • Robert W. and Vivian K. Cahill Professor in Cancer Research, Emeritus
    Member, Stanford Cancer Institute
    Research Interest

    Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory. He is actively engaged in undergraduate teaching and course development in the medical school

  • Professor of Medicine (Immunology and Rheumatology)
    Member, Stanford Cancer Institute
    Clinical Focus
    • Immunology and Rheumatology
    • Allergy and Immunology
    Research Interest

    My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have identified and characterized a gene (GRAIL) that seems to control T cell anergy. We have recently characterized a gene (Deaf1) that seems to play a major role in peripheral tolerance in T1D.

  • Edward C. and Amy H. Sewall Professor II in the School of Medicine, Emeritus
    Member, Stanford Cancer Institute
    Clinical Focus
    • Head and Neck Cancer
    • Otolaryngology
    • Head and Neck Tumor Surgery
  • Assistant Professor of Pediatrics (Endocrinology)
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Pediatric Endocrinology
    Research Interest

    The overall goal of our research is to understand on both a molecular and systemic level how hormones regulate stem cell fate decisions and the role these pathways play in both physiology and disease. We use molecular biology and in vivo models to elucidate mechanisms of regulating cell fate determination by the endocrine system. Understanding these processes has profound and broad implications for both science and health.

  • Professor of Medicine (Endocrinology, Gerontology and Metabolism), Emeritus
    Member, Stanford Cancer Institute
    Clinical Focus
    • Endocrinology
    • Internal Medicine
    Research Interest

    Studies of the role of the vitamin D receptor in the action of 1,25-dihydroxyvitamin D, the active vitamin D hormone. Current efforts are evaluating the vitamin D receptor in breast and prostate cancer, osteoporosis and rickets.

  • Burnet C. and Mildred Finley Wohlford Professor in the School of Humanities and Sciences
    Member, Bio-X
    Member, Stanford Cancer Institute
    Affiliate, Stanford Woods Institute for the Environment
    Research Interest

    Human genetic and cultural evolution, mathematical biology, demography of China

  • Professor of Medicine (Oncology) and of Pathology
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Hodgkin's Disease
    • Hodgkin's Disease - Hematology
    • Hodgkin's Disease - Medical Oncology
    Research Interest

    My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation.

  • Benjamin Scott Crocker Professor of Human Biology
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    In the course of evolution,two of the strongest selective forces in nature,light and sex, have left their mark on living organisms. I am interested in how the development and function of the nervous system reflects these events. In the visual system, we are studying the cellular basis of retinal development. In the reproductive system, we have indentified a collection of cells in the brain containing gonodotropin releasing hormone(GnRH)

  • Professor of Chemical and Systems Biology and of Biochemistry
    Member, Stanford Cancer Institute
    Research Interest

    My lab has two main goals: to understand mitotic regulation and to understand the systems-level logic of simple signaling circuits. We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study. We also carry out single-cell fluorescence imaging studies on mammalian cell lines. Our experimental work is complemented by computational and theoretical studies aimed at identifying the design principles of regulatory circuits.

  • George D. Smith Professor in Molecular and Genetic Medicine and Professor of Genetics
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Research Interest

    We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".

  • Colleen Haas Chair in the School of Medicine
    Member, Stanford Cancer Institute
    Clinical Focus
    • GI Oncology
    • Medical Oncology
    • Oncology
    Research Interest

    Clinical expertise in GI cancers with research which emphasizes Phase I and II clinical trials of novel therapies but also includes translational studies including biomarkers, molecular imaging, tumor immunology and development of immunotherapeutic trials.

  • Bing Director of the Program in Human Biology, Beirne Family Professor of Pediatric Neuro-Oncology & Prof of Pediatrics &, by courtesy, of Neurosurgery at SUMC
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Neuro Oncology
    • Neurology - Child Neurology
    • Neuro-Oncology
    Research Interest

    Clinical neuro-oncology: My research explores the epidemiology, natural history, and disease patterns of brain tumors in childhood, as well as prospective clinical trials for treating these neoplasms. Research interests also include neurologic effects of cancer and its therapies, and childhood headaches.

  • Associate Professor of Medicine (Oncology) and of Genetics and, by courtesy, of Pediatrics
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • GI Oncology
    • Cancer Genetics
    • Gastrointestinal Cancers - Genetics
    Research Interest

    Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA damage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.

  • C.F. Rehnborg Professor in Disease Prevention, Emeritus
    Member, Stanford Cancer Institute
    Clinical Focus
    • Cardiology (Heart), Preventive
    • Internal Medicine
    • Primary Prevention
    Research Interest

    Population-level (community) prevention of cardiovascular disease, epidemiology and prevention of chronic diseases, tobacco use cessation research, tobacco control policy, nutrition education, blood pressure control, and lipid disorders.

  • Assistant Professor of Biology
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Research Interest

    We study the regulation and evolution of gene expression using a combination of experimental and computational approaches.

    Our work brings together quantitative genetics, genomics, epigenetics, and evolutionary biology to achieve a deeper understanding of how genetic variation within and between species affects genome-wide gene expression and ultimately shapes the phenotypic diversity of life.

  • Consulting Professor, Health Research & Policy
    Member, Stanford Cancer Institute
    Research Interest

    Chronic disease epidemiology, particularly cancer, cardiovascular disease, adverse effects of smoking, alcohol and pharmaceuticals, evaluation of screening tests.
    Most of my career has been in the Kaiser Permanente Division of Research where I was Director for 7 years and am still active. I especially enjoy mentoring students and trainees at Stanford.

  • Professor of Biology
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    The long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.

  • Reed-Hodgson Professor in Human Biology and Professor of Genetics
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    Regulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis.

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