Cancer Institute A national cancer institute
designated cancer center

Department: Stanford Cancer Institute

A

  • Saul A. Rosenberg, MD, Professor of Lymphoma
    Member, Stanford Cancer Institute
    Clinical Focus
    • Lymphoma
    • Burkitt's Lymphoma
    • Hodgkin's Disease
    Research Interest

    Clinical investigation in Hodgkin's disease, non-Hodgkin's Lymphomas and cutaneous lymphomas. Experimental therapeutics with novel chemotherapy and biologically targeted therapies.

    The research program is highly collaborative with radiation oncology, industry, pathology and dermatology.

  • Associate Professor of Pediatrics (Stem Cell Transplantation) at the Lucile Salter Packard Children's Hospital
    Member, Stanford Cancer Institute
    Clinical Focus
    • Blood and Marrow Transplantation, Pediatric
    • Hematology/Oncology/Stem Cell Transplant, Pediatric
    • Pediatric Hematology-Oncology
    Research Interest

    Hematopoietic Stem cell biology-created a SCID mouse model to study engraftment of cord blood derived hematopoietic cells and use of this model to develop gene transfer technology for Fanconi anemia.Clinical research interests are to develop new protocols to reduce toxicity from high doses of chemotherapy and radiation therapy and development of a comprehensive late effects clinic for the long term follow up of transplant patients.

  • Assistant Professor of Medicine (Oncology)
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Lymphoma
    • Lymphoma
    • B-Cell Chronic Lymphocytic Leukemia
    Research Interest

    My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.

    Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials.

  • Kenneth Fong Professor and Professor of Bioengineering, of Genetics, of Medicine (General Medical Discipline) and, by courtesy, of Computer Science
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Internal Medicine
    Research Interest

    I refer you to my web page for detailed list of interests, projects and publications. In addition to pressing the link here, you can search "Russ Altman" on http://www.google.com/

  • Assistant Professor of Medicine (Endocrinology)
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Internal Medicine
    • Pheochromocytoma and Paraganglioma
    • Hereditary Endocrine Disorders
    Research Interest

    The ANNES LABORATORY of Molecular Endocrinology: Leveraging Chemical Biology to Treat Endocrine Disorders

    DIABETES
    The prevalence of diabetes is increasing at a staggering rate. By the year 2050 an astounding 25% of Americans will be diabetic. The goal of my research is to uncover therapeutic strategies to stymie the ensuing diabetes epidemic. To achieve this goal we have developed a variety of innovate experimental approaches to uncover novel approaches to curing diabetes.

    (1) Beta-Cel

  • Clinical Focus
    • Psychology
    • Behavior Therapy
    • Interpersonal Relations
    Research Interest

    Teaching & clinical interests include: Supervision, training, and mentoring of postdoctoral fellows and residents; consultation. Brief and long-term therapy: CBT, IPT, mood regulation & psychodynamic approaches.

  • Assistant Professor of Medicine (Blood and Marrow Transplantation) at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Blood and Marrow Transplant
    • Hematology
    • Blood and Marrow Transplantation
    Research Interest

    Research interest in utilizing post-transplant adoptive cellular immunotherapy to reduce GVHD and relapse in patients with high risk hematologic malignancies.

  • Ronald F. Dorfman, MBBch, FRCPath Professor in Hematopathology
    Member, Stanford Cancer Institute
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Hematopathology
    • Pathology
    Research Interest

    I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors.

  • Professor of Medicine (Hematology) and of Biochemistry
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • Hematology
    • Medical Oncology
    Research Interest

    Telomeres are nucleoprotein complexes that protect chromosome ends and shorten with cell division and aging. We are interested in how telomere shortening influences cancer, stem cell function, aging and human disease. Telomerase is a reverse transcriptase that synthesizes telomere repeats and is expressed in stem cells and in cancer. We have found that telomerase also regulates stem cells and we are pursuing the function of telomerase through diverse genetic and biochemical approaches.

  • Vice Provost and Dean of Research, Lucile Salter Packard Professor of Pediatrics and Professor of Microbiology and Immunology
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Infectious Diseases, Pediatric
    • Pediatric Infectious Disease
    Research Interest

    Our laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections.

  • Professor of Radiation Oncology (Radiation Biology) and of Genetics
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Research Interest

    Our research is aimed at defining the pathways of p53-mediated apoptosis and tumor suppression, using a combination of biochemical, cell biological, and mouse genetic approaches. Our strategy is to start by generating hypotheses about p53 mechanisms of action using primary mouse embryo fibroblasts (MEFs), and then to test them using gene targeting technology in the mouse.

  • Professor of Pathology
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    Genetic and cell biological analyses of signals controlling cell polarity and morphogenesis. Frizzled signaling and cytoskeletal organization.

B

  • Associate Professor of Bioengineering
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    Biophysical mechanisms of host defense peptides (a.k.a. "antimicrobial peptides") and mimics; also, molecular and cellular biophysics of human innate immune responses.

  • The Ernest and Amelia Gallo Professor in the School of Medicine and Professor of Developmental Biology
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    Function of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.

  • Professor of Radiology (General Radiology) and, by courtesy, of Orthopaedic Surgery at the Stanford University Medical Center
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • Diagnostic Radiology
    • Radiology
    Research Interest

    Applications of computer graphics to medical imaging, with emphasis on diagnosis of bowel pathology using virtual colonoscopy. Dynamic joint imaging with open Magnetic Resonance Imaging system.

  • Associate Professor of Developmental Biology, of Computer Science and of Pediatrics (Genetics)
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Member, Stanford Neurosciences Institute
    Research Interest

    Dr. Bejerano, co-discoverer of ultraconserved elements, studies the Human Genome. His research focuses on genome sequence and function in both humans and related primate, mammalian and vertebrate species. He is deeply interested in mapping both coding and non-coding genome sequence variation to phenotype differences, and in extracting specific genetic insights from high throughput sequencing measurements, in the contexts of development and developmental abnormalities.

  • Laurie Kraus Lacob Professor
    Member, Stanford Cancer Institute
    Clinical Focus
    • Gynecologic Cancer
    • Gynecologic Oncology
    • Gynecologic Cancers - Gynecologic Oncology
  • Associate Professor of Biology
    Member, Bio-X
    Member, Stanford Cancer Institute
    Research Interest

    We use genetic, genomic and cell biological approaches to study cell fate acquisition, focusing on cases where cell fate is correlated with asymmetric cell division.

  • Alfred Woodley Salter and Mabel Smith Salter Endowed Professor in Pediatrics
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Pediatric Cardiology
    • Pediatric Heart Transplantation
    • Pediatric Heart Failure
    Research Interest

    1. Role of the G protein coupled receptors in regulating mitochondrial structure and function.
    2. Differences between R and L ventricular responses to stress, including gene expression and miR regulation.
    3. Using iPSC-derived myocytes to understand heart failure and congenital heart disease.
    4. Tools for evaluation of cardiac physiology in transgenic mice and isolated cardiomyocytes.
    5. Anti-body mediated rejection.
    6. Biomarkers for post-transplant lymphoproliferative disorder.

  • Clinical Associate Professor, Medicine - Hematology
    Member, Stanford Cancer Institute
    Clinical Focus
    • Hematology
    • Hemostasis Thrombosis
    • Anticoagulation
  • Associate Professor of Radiology (Pediatric Radiology) and, by courtesy, of Pediatrics
    Member, Stanford Cancer Institute
    Clinical Focus
    • Diagnostic Radiology
    • Radiology
    • Radiology, Pediatric
    Research Interest

    Studies on apoptotic cell death in vivo using the H MRS phenomenon.

  • The Donald E. and Delia B. Baxter Foundation Professor and Director, Baxter Laboratory for Stem Cell Biology
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Research Interest

    Prof. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.

  • Professor of Medicine (Oncology) at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Breast Cancer
    • Medical Oncology
    • Cancer Survivorship
    Research Interest

    Use of medical informatics to improve quality delivery in cancer care

  • Larry and Sharon Malcolmson Professor in the School of Medicine
    Member, Stanford Cancer Institute
    Member, Stanford Neurosciences Institute
    Clinical Focus
    • Otolaryngology
    • Otolaryngology - Head & Neck Surgery (Ear, Nose and Throat)
    • Cochlear Implantation
    Research Interest

    Inner ear microendoscopy -- Developing techniques for minimally-invasive imaging of inner ear microanatomy and neural pysiology. Applications include improved cochlear implant development, inner ear regenerative techniques, inner ear surgery, and auditory physiology.

    Microsurgical robotics -- Developing scalable microsurgical instrumentation and robotic techniques for use in head and neck surgery.

    Surgical Simulation -- Immersive environment for temporal bone surgical simulation.

  • Professor (Research) of Health Research and Policy, Emeritus
    Member, Stanford Cancer Institute
  • Professor of Obstetrics and Gynecology (General Gynecology) at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Obstetrics and Gynecology
    • Gynecology
    • Advanced Contraception
    Research Interest

    Improving Access to Family Planning Services in Low Resource Settings:

    Through a collaboration with Population Services International, the Stanford Program for International Reproductive Education and Services (SPIRES) provides technical direction in a program designed to improve access to and uptake of family planning, particularly Long Acting Reversible Contraception (LARC) such as IUDs and implants, in 14 developing countries globally. The first year saw insertion of over 280,000 IUDs.

  • Professor of Pathology and of Microbiology and Immunology and, by courtesy, of Chemical and Systems Biology
    Member, Bio-X
    Member, Stanford Cancer Institute
    Faculty Fellow, Stanford ChEM-H
    Research Interest

    Our lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include:

    1) Design and synthesis of novel chemical probes for each of the primary protease families.

    2) Understanding the role of proteolysis in the life cycle of the human parasites, Plasmodium falciparum and Toxoplasma gondii.

    3) Defining the specific functional roles of proteases during the process of tumorogenesis.

    4) In vivo imaging of protease activity

  • Professor of Comparative Medicine and, by courtesy, of Pathology at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Affiliate, Stanford Woods Institute for the Environment
    Research Interest

    Research interests: ocular pathology, host-pathogen interactions in infectious disease, infectious disease in frogs, phenotypic characterization of tg and ko mice, histopathology of minimally-invasive radiological ablation techniques (focused ultrasound, cryoablation).

  • Vice Dean of the School of Medicine and Professor of Medicine (Hematology)
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • Hematology
    • Hematology
    • Multiple Myeloma
    Research Interest

    Regulation of expression of oncogenes in normal and malignant hematologic cells.

  • Assistant Professor of Pathology at the Stanford University Medical Center
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Hematopathology
    Research Interest

    Our goal is to understand the lymphocyte genotype-phenotype relationships in healthy human immunity and in immunological diseases. We apply new technologies and data analysis approaches to this challenge, particularly high-throughput DNA sequencing and single-cell monoclonal antibody generation, in parallel with other functional assays.

  • Keith and Jan Hurlbut Professor in the Stanford University School of Medicine
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • Urologic Oncology
    • Male Cancers - Prostate
    • Prostate Cancer
    Research Interest

    We use genomic approaches to identify disease biomarkers. We are most interested in translating biomarkers into clinical practice in urological diseases with a particular focus in cancer.

  • Professor of Medicine (Blood and Marrow Transplantation) at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Blood and Marrow Transplant
    • Blood and Marrow Transplantation
    • Blood and Marrow Transplantation / Infectious Diseases
  • Professor of Radiation Oncology, Emeritus
    Member, Stanford Cancer Institute
    Research Interest

    We seek to understand the mechanisms responsible for the resistance of cancers to treatment and to develop strategies to overcome these resistances. We are using molecular and cellular techniques and mouse models to potentiate the activity of radiation on tumors by inhibiting the bone marrow rescue of the tumor vasculature following therapy.

  • Professor of Biochemistry
    Member, Stanford Cancer Institute
    Research Interest

    Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program. The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer.

  • Associate Professor of Genetics
    Member, Bio-X
    Member, Stanford Cancer Institute
    Member, Stanford Neurosciences Institute
    Research Interest

    Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

  • Assistant Professor of Cardiothoracic Surgery (Thoracic Surgery) at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Sarcoma
    • Thoracic Oncology
    • Cardiothoracic Surgery
  • Professor of Genetics and, by courtesy, of Biology
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Research Interest

    My research focuses on analyzing genome wide patterns of variation within and between species to address fundamental questions in biology, anthropology, and medicine. My group works on a variety of organisms and model systems ranging from humans and other primates to domesticated plant and animals. Much of our research is at the interface of computational biology, mathematical genetics, and evolutionary genomics.

  • Klaus Bensch Professor in Pathology
    Member, Bio-X
    Member, Stanford Cancer Institute
    Member, Stanford Neurosciences Institute
    Clinical Focus
    • Pathology Anatomic
    • Pathology and Laboratory Medicine
    Research Interest

    Our interests include:
    1) The physiology and significance of lymphocyte homing in local and systemic immunity;
    2) biochemical and genetic studies of molecules that direct leukocyte recruitment;
    3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines;
    4) vascular differentiation in normal and pathologic inflammatory states;
    5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs.

  • Associate Professor of Pediatrics (Systems Medicine) & of Genetics and, by courtesy, of Computer Science, of Medicine (Immunology) & (BMIR) & of Pathology
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Affiliate, Stanford Woods Institute for the Environment
    Research Interest

    The Butte Lab at Stanford builds and applies tools that convert more than 300 billion points of molecular, clinical, and epidemiological data -- measured by researchers and clinicians over the past decade -- into diagnostics, therapeutics, and new insights into disease.

  • Assistant Professor of Pediatrics (Immunology)
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Allergy and Immunology
    • Pediatric Allergy/Immun
    Research Interest

    Our laboratory's goal is to address fundamental and therapeutic questions in immunology using innovative nanotechnological and biophysical approaches to visualize and manipulate cells. Our primary focus is on understanding the molecular controls that balance T cell activation versus tolerance. The ultimate aim of our work is to manipulate T cell signaling pathways to control immunologically-mediated diseases.

  • Associate Professor of Radiation Oncology (Radiation Therapy) at the Stanford University Medical Center
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • Radiation Oncology
    • Urologic Oncology
    • Prostate Cancer

C

  • Professor of Mechanical Engineering
    Member, Stanford Cancer Institute
  • Professor of Medicine (Oncology and General Internal Medicine/Medical Informatics) at the Stanford University Medical Center, Emeritus
    Member, Stanford Cancer Institute
    Clinical Focus
    • Medical Oncology
    • Breast Cancer
    • Breast Cancer Prevention
    Research Interest

    Clinical investigations in breast cancer include institutional and NSABP studies of chemoprevention, adjuvant therapy, psychosocial interventions, treatment of metastatic disease, methods of decreasing anthracycline cardiotoxicity, and modulation of multidrug resistance. Research in meta-analysis includes the performance of meta-analysis in a wide variety of settings in cancer treatment by the international Meta-Analysis Group in Cancer.

  • Assistant Professor of Anesthesiology, Perioperative and Pain Medicine at the Stanford University Medical Center
    Member, Stanford Cancer Institute
    Clinical Focus
    • Pain Management
    • Neuropathic Pain
    • Anesthesia
    Research Interest

    Factors causing prolonged post-surgical pain and prolonged opioid use.

  • Professor of Medicine (Gastroenterology and Hepatology)
    Member, Stanford Cancer Institute
    Clinical Focus
    • Gastroenterology
    • Inflammatory Bowel Diseases
    Research Interest

    Molecular mechanisms of intestinal cell growth control; function and regulation of the Src family of tyrosine kinases in normal cells, and their deregulation in cancer cells.

  • Assistant Professor of Dermatology at the Stanford University Medical Center
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Cutaneous (Dermatologic) Oncology
    • Dermatology
    • Skin Cancer
    Research Interest

    Our current studies focus on aging and skin cancers in human beings and are clinical and translational in nature:
    1) genetics and epigenetics to promote healthy aging of human skin
    2) genetics and epigenetics of human non-melanoma skin cancers and drug resistance
    3) novel therapies to promote healthy aging of the skin
    4) novel therapies for non-melanoma skin cancers

  • Associate Professor of Radiation Oncology (Radiation Therapy) at the Stanford University Medical Center
    Member, Bio-X
    Member, Stanford Cancer Institute
    Clinical Focus
    • GI Oncology
    • Head and Neck Cancer
    • Radiation Oncology
    Research Interest

    I specialize in the treatment of gastrointestinal malignancies. I am interested in developing stereotactic body radiotherapy for tumors of the liver, both primary and metastatic. I am interested in developing functional imaging as a means of determining treatment response with radiation. I am also interested in developing image-guided radiotherapy to improve radiation delivery for GI cancers to reduce toxicity and improve disease outcome.

  • Research Interest

    Dr. Chang's research interests and activities include:

    • The etiology of virus-associated malignancies, including Hodgkin lymphoma, nasopharyngeal carcinoma, and hepatocellular carcinoma

    • The etiologic role of immune-related risk factors in cancer, especially lymphoid malignancies

    • The prevention of hepatitis B and hepatocellular carcinoma

    • Racial/ethnic disparities in cancer incidence and survival, particularly among Asians and Asian Americans

  • Professor of Dermatology
    Member, Bio-X
    Member, Child Health Research Institute
    Member, Stanford Cancer Institute
    Clinical Focus
    • Cutaneous (Dermatologic) Oncology
    • Dermatology
    • General Dermatology
    Research Interest

    Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.

  • Robert C. and Jeannette Powell Neurosciences Professor
    Member, Stanford Cancer Institute
    Clinical Focus
    • Neuro Oncology
    • Brain / Central Nervous System Tumors
    • Brain / Central Nervous System Tumors - Neuro Oncology
    Research Interest

    Clinical research includes studies in the treatment of cerebrovascular disorders, such as aneurysms and AVMs, as well as the use of radiosurgery to treat tumors and vascular malformations of the brain and spine.

    Dr. Chang is C0-Director of the Cyberknife Radiosurgery Program.

    Dr. Chang is also the head of the The Stanford Neuromolecular Innovation Program with the goal of developing new technologies to improve the diagnosis and treatment of patients affected by neurological conditions.

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