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Maxence Nachury

Academic Appointments

  • Assistant Professor of Molecular and Cellular Physiology

Key Documents

Contact Information

  • Academic Offices
    Personal Information
    Email Tel (650) 721-1999
    Alternate Contact
    Jzesern Tan Administrative assistant Tel Work 650-725-4900

Bio

Academic Appointments

Honors and Awards

  • Early Career Life Scientist Award, American Society for Cell Biology (2011)
  • Searle Scholar, Searle Scholar Program (2010-2013)
  • Fellowship Award in the Neurosciences, The Esther A. & Joseph Klingenstein Fund (2009-2012)
  • Sloan Research Fellowship, Alfred P. Sloan Foundation (2009-2011)
  • Basil O'Connor Award, March of Dimes (2009-2011)
  • Scientist Development Award, American Heart Association (2009-2012)
View All 10honors and awards of Maxence Nachury

Professional Education

Postdoc: Genentech, Cell Biology and Biochemistry (2007)
Ph.D.: UC Berkeley and Université Paris-Orsay, Molecular and Cellular Biology (2001)
B.Sc.: Ecole Normale Supérieure (Paris), Biology and Biochemistry (1997)

Research & Scholarship

Current Research and Scholarly Interests

Our laboratory investigates the molecular principles of primary cilium assembly and function. Shaped like an antenna projecting out of the cell, the primary cilium exposes receptors for diverse stimuli (like platelet-derived growth factors, Hedgehog morphogens and olfactory cues) and concentrates their downstream signaling machinery to send specific molecular responses back into the cell. Despite these fascinating properties, the cilium has historically been the least studied cellular organelle and most of the fundamental questions concerning cilium biogenesis and function remain unanswered. Nowhere is our knowledge gap more striking than for the ciliopathies, a class of inherited disorders of the cilium whose central features include obesity, kidney malformations and retinal degeneration. We thus intend to uncover the molecular machines that build cilia and convey information into and out of cilia by applying proteomics, cellular imaging and in vitro reconstitution assays to entry points provided by human genetics.

The central projects of the lab currently are "Trafficking of signaling receptors to the primary cilium" and "Functional roles of the tubulin code"

Teaching

Courses

2013-14

Prior Year Coursescourses of Maxence Nachury

Graduate and Fellowship Program Affiliations

Publications

Publications

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Publication Topics

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