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Katrin Chua

Academic Appointments

  • Associate Professor of Medicine (Endocrinology, Gerontology and Metabolism)

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Contact Information

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Bio

Academic Appointments

Honors and Awards

  • Ellison Medical Foundation New Scholar in Aging, Ellison Medical Foundation/AFAR (2008-2012)
  • Paul Beeson Scholar in Aging Research, National Institute on Aging/American Federation for Aging Research (2006-)
  • Pfizer Postdoctoral Fellow in Rheumatology/Immunology, Pfizer (2002-2005)
  • Fellow of the Jane Coffin Childs Memorial Fund For Medical Research, Jane Coffin Childs Memorial Fund For Medical Research (2001-2002)
  • Sackler Scholar in Psychobiology, Harvard University (1995-1996)

Professional Education

Ph.D.: Harvard Medical School, Neuroscience/Cell Biology (2001)
M.D.: Harvard Medical School, Medicine (2001)
B.A.: Harvard University, Biochemistry/Molecular Biology (1991)

Research & Scholarship

Current Research and Scholarly Interests

Our lab is interested in understanding molecular processes that underlie aging and age-associated pathologies in mammals. We focus on a family of genes, the SIRTs, which regulate stress resistance and lifespan in lower organisms such as yeast, worms, and flies. In mammals, we recently uncovered a number of ways in which SIRT factors may contribute to cellular and organismal aging by regulating resistance to various forms of stress. We have now begun to characterize the molecular mechanisms by which these SIRT factors function. In particular, we are interested in how SIRT factors regulate chromatin, the molecular structure in which the DNA of mammalian genomes is packaged, and how such functions may link genome maintenance to stress resistance and aging.

Teaching

Courses

2013-14

Postdoctoral Advisees

Zaneta OdrowazLida ParedesLuisa Tasselli

Graduate and Fellowship Program Affiliations

Publications

Publications

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